GLYCINE ( DrugBank: Glycine )

5 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
35	天疱瘡	1
60	再生不良性貧血	2
86	肺動脈性肺高血圧症	1
226	間質性膀胱炎（ハンナ型）	1
299	嚢胞性線維症	2

35. 天疱瘡

臨床試験数 : 99 / 薬物数 : 124 - (DrugBank : 36) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 169

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2013-000211-24-DE (EUCTR)	01/10/2013	08/07/2013	immunoglobulin infusion as adjuvant therapy in patients with Pemphigus Vulgaris	A multicenter, randomized, placebo-controlled, double-blind proof of concept study to evaluate the e ...	patients with Pemphigus vulgaris MedDRA version: 16.0;Level: LLT;Classification code 10052802;Term: ...	Trade Name: Intratect 5% Product Name: Intratect Other descriptive name: WATER FOR INJECTION Other desc ...	Ruprecht-Karls-University Heidelberg	NULL	Not Recruiting			Female: yes Male: yes	10	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	Germany

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60. 再生不良性貧血

臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2007-000902-55-FR (EUCTR)	23/04/2008	04/10/2007	Prospective Phase II Pilot study of Rabbit Antithymocyte globulin (ATG, Thymoglobuline®, Genzyme) wi ...	Prospective Phase II Pilot study of Rabbit Antithymocyte globulin (ATG, Thymoglobuline®, Genzyme) wi ...	Aquired aplastic anaemia and transfusion dependent non-severe aplastic anaemia MedDRA version: 9.1;L ...	Trade Name: Thymoglobuline Product Name: Thymoglobuline®/Thymoglobulin® Product Code: anti-thymocyte g ...	EBMT (European group for Blood and Marrow Transplantation)	NULL	Not Recruiting			Female: yes Male: yes	35	Phase 2	France;Germany;United Kingdom
2	EUCTR2007-000902-55-GB (EUCTR)	19/09/2007	26/06/2007	Prospective Phase II study of Rabbit Antithymocyte globulin (ATG, Thymoglobuline®, Genzyme) with Cic ...	Prospective Phase II study of Rabbit Antithymocyte globulin (ATG, Thymoglobuline®, Genzyme) with Cic ...	Acquired severe aplastic anaemia and transfusion dependent non-severe aplastic anaemia MedDRA versio ...	Trade Name: Thymoglobuline Product Name: Thymoglobuline®/Thymoglobulin® Product Code: anti-thymocyte g ...	EBMT (European group for Blood and Marrow Transplantation)	NULL	Not Recruiting			Female: yes Male: yes	35	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	France;Germany;United Kingdom

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86. 肺動脈性肺高血圧症

臨床試験数 : 1,205 / 薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-002943-92-NL (EUCTR)	07/11/2011	22/08/2011	Study of a new thermostable formulation of Flolan™ to treat Pulmonary Arterial Hypertension (PAH)	A Single-arm, Open Label Study Evaluating the Impact on Lifestyle of a New Thermo Stable Formulation ...	pulmonary arterial hypertension (PAH) MedDRA version: 14.1;Level: PT;Classification code 10064911;Te ...	Trade Name: FLOLAN™ and GlycineDiluent Product Name: FLOLAN™ and GlycineDiluent Product Code: 4AU76 INN ...	GlaxoSmithKline Research and Development Limited	NULL	Not Recruiting			Female: yes Male: yes	20		United States;Canada;Netherlands

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226. 間質性膀胱炎（ハンナ型）

臨床試験数 : 145 / 薬物数 : 156 - (DrugBank : 51) / 標的遺伝子数 : 64 - 標的パスウェイ数 : 146

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JMA-IIA00113	27/02/2013	01/03/2013	Multi-center clinical study on the effect of glycine for disorders of urine storage	Multi-center clinical study on the effect of glycine for disorders of urine storage	Overactive bladder, chronic prostatitis, interstitial cystitis, and nocturia	Intervention type:DRUG. Intervention1:glycine, Dose form:POWDER, Route of administration:ORAL, inten ...	Kimio Sugaya (Kitakami Central Hospital, and Southern Knights' Laboratory LLP)	Okinawa Kyodo Hospital, Kawahara Nephro-urology Clinic, Yamada Urologic Clinic, Akita Urologic Clini ...	Completed	>=20 YEARS	No Limit	BOTH	160	NOT APPLICABLE	Japan

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299. 嚢胞性線維症

臨床試験数 : 1,695 / 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03617718 (ClinicalTrials.gov)	November 1, 2018	19/7/2018	Project 2 Airway Potential Hydrogen (pH) in Asthma	Methods to Identify and Treat Severe Asthma Patients Project 2: Airway pH Phenotyping	Cystic Fibrosis;Asthma;Severe Persistent Asthma;Healthy	Drug: Glycine Buffer	University Hospitals Cleveland Medical Center	National Institutes of Health (NIH);National Heart, Lung, and Blood Institute (NHLBI)	Recruiting	18 Years	50 Years	All	75	Phase 1/Phase 2	United States
2	NCT01417481 (ClinicalTrials.gov)	March 2012	15/8/2011	Effect of Glycine in Cystic Fibrosis	Evaluation of the Capability of a GlycineOral Supplement for Diminishing Bronchial Inflammation in C ...	Cystic Fibrosis	Dietary Supplement: Glycine;Dietary Supplement: Placebo	Instituto Nacional de Enfermedades Respiratorias	Hospital Infantil de Mexico Federico Gomez;Instituto Mexicano del Seguro Social	Terminated	5 Years	15 Years	All	13	Phase 2	Mexico

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