DMARD ( DrugBank: - )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
46	悪性関節リウマチ	482

46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05545020 (ClinicalTrials.gov)	December 25, 2022	9/9/2022	Trivalent Chromium Treatment for Rheumatoid Arthritis	Trivalent Chromium as a Treatment for Rheumatoid Arthritis Patients	Rheumatoid Arthritis	Drug: Trivalent chromium versus synthetic and/ or biological DMARDs	Alexandria University	NULL	Recruiting	18 Years	80 Years	All	60	Phase 2/Phase 3	Egypt
2	NCT05516979 (ClinicalTrials.gov)	September 26, 2022	24/8/2022	A Safety & Efficacy Study of Treatment With AP1189 in Rheumatoid Arthritis Patients naïve to DMARDTr ...	A Double-blind, Multi-center, Randomized, Placebo-controlled Study of the Safety and Efficacy of 12 ...	Rheumatoid Arthritis	Drug: 100 mg AP1189;Drug: Placebo	SynAct Pharma Aps	NBCD A/S	Recruiting	18 Years	85 Years	All	120	Phase 2	Moldova, Republic of
3	NCT05447520 (ClinicalTrials.gov)	July 15, 2022	1/7/2022	Montelukast Use in Rheumatoid Arthritis	Clinical Study Evaluating the Efficacy and Safety of Adjunctive Use of Montelukast in Rheumatoid Art ...	Rheumatoid Arthritis	Drug: Montelukast;Drug: Placebo;Drug: Conventional DMARDs	Noha Mansour	NULL	Recruiting	18 Years	80 Years	All	50	Phase 2	Egypt
4	NCT05165771 (ClinicalTrials.gov)	July 2022	8/12/2021	Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 in Participants With Active Rheumato ...	A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2 Proof-of-Concept Study to Evalu ...	Rheumatoid Arthritis	Drug: GS-5718;Drug: Placebo to match GS-5718;Drug: Tofacitinib 5 mg;Drug: Placebo to match Tofacitin ...	Gilead Sciences	NULL	Withdrawn	18 Years	75 Years	All	0	Phase 2	NULL
5	NCT05671627 (ClinicalTrials.gov)	February 2, 2022	19/9/2022	Cortisol Circadian Rhythm in Patients With RA	An Impaired Functional Reserve of Adrenal Cortex May Associate With difficult-to Treat RA: Can a Dis ...	Rheumatoid Arthritis	Drug: DMARDs	National and Kapodistrian University of Athens	NULL	Recruiting	20 Years	80 Years	All	50		Greece
6	ChiCTR2100052492	2022-01-01	2021-10-29	A clinical study on the treatment of refractory rheumatoid arthritis in combination with single Chin ...	A clinical study on the treatment of refractory rheumatoid arthritis in combination with single Chin ...	Rheumatoid Arthritis	Group 1:On the basis of traditional DMARDtreatment, add traditional Chinese medicine Danshen tablets ...	The Second Affiliated Hospital of Guangxi Medical University	NULL	Pending	18	80	Both	Group 1:25;Group 2:25;Group 3:25;Group 4:25;	Phase 4	China
7	NCT04692493 (ClinicalTrials.gov)	September 22, 2021	15/12/2020	RA-PRO PRAGMATIC TRIAL	A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients With Rheumatoid Art ...	Rheumatoid Arthritis	Drug: targeted synthetic DMARD class;Drug: non-TNFi-biologic class	University of Alabama at Birmingham	Patient-Centered Outcomes Research Institute	Recruiting	18 Years	N/A	All	924	Phase 3	United States
8	ITMCTR2200005771	2021-07-17	2021-07-16	Evidence based evaluation of a synergistic protocol for Chinese and Western medicine in active rheum ...	Evidence based evaluation of a synergistic protocol for Chinese and Western medicine in active rheum ...	Rheumatoid Arthritis	The combination of Chinese and Western Medicine Group:Western medicine +Modified Yunpi Jiedu Tongluo ...	Zhejiang Chinese Medical University	NULL	Pending	18	65	Both	The combination of Chinese and Western Medicine Group:659;Western Medicine Group:659;	N/A	China
9	ChiCTR2100048795	2021-07-17	2021-07-16	Evidence based evaluation of a synergistic protocol for Chinese and Western medicine in active rheum ...	Evidence based evaluation of a synergistic protocol for Chinese and Western medicine in active rheum ...	Rheumatoid Arthritis	Western Medicine Group:Methotrexate and other traditional DMARDs treatment;The combination of Chines ...	Zhejiang Chinese Medical University	NULL	Pending	18	65	Both	Western Medicine Group:659;The combination of Chinese and Western Medicine Group:659;	N/A	China
10	ChiCTR2100048185	2021-07-01	2021-07-04	The efficacy and safety of Tofacitinib in the treatment of DMARDS naive rheumatoid arthtits patients ...	The efficacy and safety of Tofacitinib virus MTX in the treatment of DMARDS naive rheumatoid arthtit ...	Rheumatoid Arthritis	Experimental group:Tofacitinib 5mg twice per day;Control group:Methotrexate;	Peking University First Hospital	NULL	Pending	18		Both	Experimental group:112;Control group:112;	Phase 4	China

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