Mesalazine ( DrugBank: Mesalazine )
3 diseases
ID | Disease name (Link within this page) | Number of trials |
---|---|---|
46 | Malignant rheumatoid arthritis | 1 |
96 | Crohn disease | 29 |
97 | Ulcerative colitis | 237 |
46. Malignant rheumatoid arthritis
Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228
Showing 1 to 1 of 1 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | JPRN-UMIN000005362 | 2011/04/01 | 01/04/2011 | Clinical study for the efficacy of mesalazine for the treatment of small bowel injury caused by non-steroidal anti-inflammatory drugs(NSAIDs). Clinical study for the efficacy of mesalazinefor the treatment of small bowel injury caused by non-s ... | Clinical study for the efficacy of mesalazine for the treatment of small bowel injury caused by non-steroidal anti-inflammatory drugs(NSAIDs). - Clinical study for the efficacy of mesalazine for the treatment of small bowel injury caused by NSAIDs. Clinical study for the efficacy of mesalazinefor the treatment of small bowel injury caused by non-s ... | Patients with rheumatoid arthritis with anemia taking NSAIDs | Treatment with mesalazine | Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine | NULL | Complete: follow-up complete | 20years-old | 70years-old | Male and Female | 13 | Not selected | Japan |
96. Crohn disease
Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209
Showing 1 to 10 of 29 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05386290 (ClinicalTrials.gov) | July 9, 2020 | 17/5/2022 | A Multicentered Prospective Cohort Study of Chinese IBD Patients | A Multicentered Prospective Cohort Study of Chinese IBD Patients Concerning Cost-effectiveness Analysis, Therapeutic Effect Predictor Exploration and Gut Microbiota Analysis A Multicentered Prospective Cohort Study of Chinese IBD Patients Concerning Cost-effectiveness Analy ... | Ulcerative Colitis;Crohn Disease | Drug: Infliximab;Drug: Vedolizumab;Drug: Ustekinumab;Drug: conventional treatment (glucocoticoid, immunosupressive drugs and/or mesalazine) Drug: Infliximab;Drug: Vedolizumab;Drug: Ustekinumab;Drug: conventional treatment (glucocoticoid, im ... | Peking Union Medical College Hospital | NULL | Enrolling by invitation | 14 Years | 80 Years | All | 200 | China | |
2 | EUCTR2018-001382-17-GB (EUCTR) | 30/10/2018 | 24/06/2019 | An investigational study to assess the safety and effectiveness of continuing existing 5-ASA medication versus stopping it. An investigational study to assess the safety and effectiveness of continuing existing 5-ASA medicat ... | Stopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-label, Non-inferiority Trial - STATIC Stopping Aminosalicylate Therapy in Inactive Crohn’s Disease (STATIC) Study: A Randomized, Open-labe ... | Inactive Crohn’s Disease;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] | INN or Proposed INN: MESALAZINE | Alimentiv Inc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 1580 | Phase 4 | Canada;United Kingdom | ||
3 | NCT02769494 (ClinicalTrials.gov) | March 2016 | 9/3/2016 | The Efficacy of Topical Mesalazine Sustained-Release Tablets in Crohn's Disease Patients With Oral Ulcer The Efficacy of Topical MesalazineSustained-Release Tablets in Crohn's Disease Patients With Oral Ul ... | The Efficacy of Topically Applied Mesalazine Sustained-Release Tablets in Oral Lesions of Crohn's Disease The Efficacy of Topically Applied MesalazineSustained-Release Tablets in Oral Lesions of Crohn's Dis ... | Crohn's Disease;Oral Ulcer | Drug: Mesalazine Sustained-Release Tablets;Drug: Riboflavin Sodium Phosphate Injection | Xijing Hospital of Digestive Diseases | NULL | Withdrawn | 18 Years | 65 Years | All | 0 | Phase 3 | China |
4 | NCT02335281 (ClinicalTrials.gov) | January 2015 | 7/1/2015 | Standardized Fecal Microbiota Transplantation for Inflammatory Bowel Disease | Efficacy, Durability and Safety of Standardized Fecal Microbiota Transplantation for Severe Inflammatory Bowel Disease Efficacy, Durability and Safety of Standardized Fecal Microbiota Transplantation for Severe Inflamma ... | Inflammatory Bowel Disease;Ulcerative Colitis;Crohn's Disease | Procedure: FMT;Drug: Mesalazine | Yanling Wei | NULL | Recruiting | 16 Years | 70 Years | Both | 40 | Phase 2 | China |
5 | NCT02044952 (ClinicalTrials.gov) | January 2014 | 19/1/2014 | Efficacy and Safety Study of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction Remission Efficacy and Safety Study of Tripterygium Glycoside in the Treatment of Crohn's Disease for Inductio ... | Prospective Experimental of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction Remission Prospective Experimental of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction ... | Inflammatory Bowel Diseases;Crohn's Disease;Gastrointestinal Diseases;Digestive System Diseases;Intestinal Diseases Inflammatory Bowel Diseases;Crohn's Disease;Gastrointestinal Diseases;Digestive System Diseases;Inte ... | Drug: Mesalazine, Tripterygium glycosides | Zhu Weiming | NULL | Recruiting | 18 Years | 75 Years | Both | 40 | Phase 2/Phase 3 | China |
6 | NCT01514240 (ClinicalTrials.gov) | February 2012 | 10/1/2012 | Phase III Study of D9421-C 9 mg in Patients With Active Crohn's Disease in Japan | A Multicentre, Double-blind, Randomised, Parallel-group, Phase III Study to Assess Efficacy and Safety of D9421-C 9 mg Versus Mesalazine 3 g in Patients With Active Crohn's Disease (CD) in Japan A Multicentre, Double-blind, Randomised, Parallel-group, Phase III Study to Assess Efficacy and Safe ... | Crohn's Disease | Drug: D9421-C capsule 3 mg;Drug: Mesalazine tablets | AstraZeneca | NULL | Completed | 15 Years | 130 Years | All | 123 | Phase 3 | Japan |
7 | EUCTR2009-011220-62-NL (EUCTR) | 26/10/2009 | 13/07/2009 | A randomized controlled withdrawal trial in Crohn's disease patients in long-term remission on mesalazine: the CROWN study A randomized controlled withdrawal trial in Crohn's disease patients in long-term remission on mesal ... | A randomized controlled withdrawal trial in Crohn's disease patients in long-term remission on mesalazine: the CROWN study A randomized controlled withdrawal trial in Crohn's disease patients in long-term remission on mesal ... | 1. Patients with a diagnosis of quiscent (CDAI < 150) Crohn's Disease (CD) according to established clinical, endoscopic, radiological and histological criteria. 2. Patients will be aged 18 years or older. 3. Patients with mesalazine maintenance therapy > 1 year. MedDRA version: 9.1;Level: LLT;Classification code 10011401;Term: Crohn's disease 1. Patients with a diagnosis of quiscent (CDAI < 150) Crohn's Disease (CD) according to established ... | Product Name: mesalazine INN or Proposed INN: mesalazine Other descriptive name: AMINOSALICYLIC ACID | University Medical Center Utrecht | NULL | Not Recruiting | Female: yes Male: yes | Netherlands | ||||
8 | NCT00862121 (ClinicalTrials.gov) | April 2009 | 13/3/2009 | A Study With Pentasa in Patients With Active Crohn's Disease | PENTASA in Active Crohn's Disease: A 10-week, Double-blind, Multi-centre Trial Comparing PENTASA Sachet 6 g/Day (Mesalazine, Mesalamine) With Placebo. PENTASA in Active Crohn's Disease: A 10-week, Double-blind, Multi-centre Trial Comparing PENTASA Sac ... | Crohn´s Disease | Drug: Pentasa;Drug: Placebo | Ferring Pharmaceuticals | NULL | Terminated | 18 Years | N/A | All | 20 | Phase 3 | United States;Belgium;Denmark;France;Germany;Sweden;United Kingdom;Spain |
9 | NCT00245505 (ClinicalTrials.gov) | February 2009 | 26/10/2005 | The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active Drug: Crohn's Disease | The Effect on Mucosal Healing With Pentasa Sachet 4g in Mild to Moderate Active Small Bowel Crohn´s Disease, Evaluated by Video Capsule Endoscopy After 6 and 12 Weeks Treatment. A Pilot Study The Effect on Mucosal Healing With Pentasa Sachet 4g in Mild to Moderate Active Small Bowel Crohn´s ... | Crohn's Disease | Drug: Mesalazine (Mesalamine) | Ferring Pharmaceuticals | NULL | Terminated | 18 Years | 70 Years | Both | 3 | Phase 3 | Sweden |
10 | EUCTR2008-002100-26-BE (EUCTR) | 28/01/2009 | 31/07/2008 | PENTASA in active Crohn’s Disease: A 10-week, double-blind, multi-centre trial comparing PENTASA Sachet 6 g/day (mesalazine, mesalamine) with placebo - PEACE PENTASA in active Crohn’s Disease: A 10-week, double-blind, multi-centre trial comparing PENTASA Sac ... | PENTASA in active Crohn’s Disease: A 10-week, double-blind, multi-centre trial comparing PENTASA Sachet 6 g/day (mesalazine, mesalamine) with placebo - PEACE PENTASA in active Crohn’s Disease: A 10-week, double-blind, multi-centre trial comparing PENTASA Sac ... | Active mild to moderate crohn's disease. MedDRA version: 9.1;Level: LLT;Classification code 10011401;Term: Crohn's disease Active mild to moderate crohn's disease. MedDRA version: 9.1;Level: LLT;Classification code 10011401 ... | Trade Name: PENTASA Sachet INN or Proposed INN: MESALAZINE Other descriptive name: Mesalamine, 5-aminosalicylic acid Trade Name: PENTASA Sachet INN or Proposed INN: MESALAZINE Other descriptive name: Mesalamine, 5-amino ... | Ferring Pharmaceuticals A/S | NULL | Not Recruiting | Female: yes Male: yes | 510 | France;Belgium;Denmark;Germany;United Kingdom;Sweden |
97. Ulcerative colitis
Clinical trials : 2,630 / Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202
Showing 1 to 10 of 237 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT05561062 (ClinicalTrials.gov) | December 1, 2022 | 27/9/2022 | Atorvastatin in Patients With Ulcerative Colitis | Combination of Atorvastatin and Mesalazine to Enhance Anti-inflammatory Effects and Attenuates Progression of Ulcerative Colitis Combination of Atorvastatin and Mesalazineto Enhance Anti-inflammatory Effects and Attenuates Progre ... | Inflammatory Bowel Diseases | Drug: Atorvastatin 80mg | Tanta University | NULL | Not yet recruiting | 18 Years | 75 Years | All | 50 | Phase 2 | NULL |
2 | ITMCTR2200006063 | 2022-06-05 | 2022-06-05 | A systematic study on the syndrome differentiation standard of lingnan wet syndrome - ulcerative colitis A systematic study on the syndrome differentiation standard of lingnan wet syndrome - ulcerative col ... | A systematic study on the syndrome differentiation standard of lingnan wet syndrome - ulcerative colitis A systematic study on the syndrome differentiation standard of lingnan wet syndrome - ulcerative col ... | Ulcerative colitis | No intervention:No intervention;Pure western medicine intervention:Mesalazine ;Intervention of integrated Chinese and Western medicine:Mesalazine + invigorating spleen and removing dampness;Simple Chinese medicine intervention:Shenling Baizhu powder + special prescription; No intervention:No intervention;Pure western medicine intervention:Mesalazine;Intervention of integr ... | Guangdong Provincial Hospital of Chinese Medicine | NULL | Pending | 18 | 75 | Both | No intervention:25;Pure western medicine intervention:25;Intervention of integrated Chinese and Western medicine:25;Simple Chinese medicine intervention:25; | Phase 1 | China |
3 | ChiCTR2200059150 | 2022-05-05 | 2022-04-26 | Study on the mechanism of Qingchangxiaopi Decoction and UC large intestine damp-heat syndrome from the activation of LPDC through TLR5-IRF4 pathway to mediate intestinal inflammation Study on the mechanism of Qingchangxiaopi Decoction and UC large intestine damp-heat syndrome from t ... | Study on the mechanism of Qingchangxiaopi Decoction and UC large intestine damp-heat syndrome from the activation of LPDC through TLR5-IRF4 pathway to mediate intestinal inflammation Study on the mechanism of Qingchangxiaopi Decoction and UC large intestine damp-heat syndrome from t ... | Ulcerative colitis (UC) | Intervention group:Qingchangxiaopi Decoction;Control group:Mesalazine; | Dongguan Hospital of Guangzhou University of Chinese Medinine | NULL | Pending | 18 | 70 | Both | Intervention group:30;Control group:30; | China | |
4 | ITMCTR2100005038 | 2021-07-15 | 2021-07-09 | Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Series of N-of-1 Randomized, Controlled Trials Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Ser ... | Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Series of N-of-1 Randomized, Controlled Trials Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Ser ... | Ulcerative Colitis | Experimental group:SLBZP Granule and Mesalazine;Control group:Mesalazine; | The First Affiliated Hospital of Guangzhou University of Chinese Medicine | NULL | Pending | 18 | 75 | Both | Experimental group:3;Control group:3; | N/A | China |
5 | ChiCTR2100048502 | 2021-07-15 | 2021-07-09 | Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Series of N-of-1 Randomized, Controlled Trials Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Ser ... | Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Series of N-of-1 Randomized, Controlled Trials Modified Shenling Baizhu Powder in the Treatment of Ulcerative Colitis in the Remission Phase: a Ser ... | Ulcerative Colitis | Experimental group:SLBZP Granule and Mesalazine;Control group:Mesalazine; | The First Affiliated Hospital of Guangzhou University of Chinese Medicine | NULL | Pending | 18 | 75 | Both | Experimental group:3;Control group:3; | N/A | China |
6 | ChiCTR2100048176 | 2021-07-12 | 2021-07-04 | A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen deficiency and dampness-blocking syndrome in remission period A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen ... | A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen deficiency and dampness-blocking syndrome in remission period A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen ... | Ulcerative colitis | Experimental group:Xuyan Decoction;Control group:Mesalazine sustained-release granules; | Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine | NULL | Pending | 18 | 65 | Both | Experimental group:44;Control group:44; | China | |
7 | ITMCTR2100005012 | 2021-07-12 | 2021-07-04 | A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen deficiency and dampness-blocking syndrome in remission period A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen ... | A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen deficiency and dampness-blocking syndrome in remission period A randomized controlled trial of Xuyan decoction in the treatment of ulcerative colitis with spleen ... | Ulcerative colitis | Control group:Mesalazine sustained-release granules;Experimental group:Xuyan Decoction; | Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine | NULL | Pending | 18 | 65 | Both | Control group:44;Experimental group:44; | China | |
8 | ChiCTR2100046446 | 2021-07-01 | 2021-05-15 | Effect of probiotics supplementation combined with WeChat platform health management on nutritional status, inflammatory factors, and quality of life in patients with mild-to-moderate ulcerative colitis Effect of probiotics supplementation combined with WeChat platform health management on nutritional ... | Effect of probiotics supplementation combined with WeChat platform health management on nutritional status, inflammatory factors, and quality of life in patients with mild-to-moderate ulcerative colitis Effect of probiotics supplementation combined with WeChat platform health management on nutritional ... | ulcerative colitis | experimental group:Bifidobacterium triple live bacteria combined with WeChat platform for health management intervention;control group:Mesalazine Oral; experimental group:Bifidobacterium triple live bacteria combined with WeChat platform for health man ... | Affiliated Hospital of Jiangnan University | NULL | Recruiting | 18 | 80 | Both | experimental group:70;control group:70; | N/A | China |
9 | EUCTR2019-003334-16-LV (EUCTR) | 29/04/2021 | 14/01/2021 | Novel budenosid suppository in addition to basic therapy with oral mesalazine compared to basic therapy alone for treatment of ulcerative colitis Novel budenosid suppository in addition to basic therapy with oral mesalazinecompared to basic thera ... | Randomised, double-blind, placebo-controlled, multicentre study to compare the efficacy and safety of novel 4 mg budesonide suppository in combination with oral mesalazine versus oral mesalazine monotherapy in patients with acute ulcerative colitis Randomised, double-blind, placebo-controlled, multicentre study to compare the efficacy and safety o ... | acute ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10066678;Term: Acute ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] acute ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10066678;Term: Acute ul ... | Product Name: Budenofalk® suppositories INN or Proposed INN: BUDESONIDE Other descriptive name: Budenofalk® suppositories (BUS) Trade Name: Salofalk 3g gastro-resistant prolonged-release granules Product Name: Salofalk 3g gastro-resistant prolonged-release granules INN or Proposed INN: MESALAZINE Product Name: Budenofalk® suppositories INN or Proposed INN: BUDESONIDE Other descriptive name: Budeno ... | Dr. Falk Pharma GmbH | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 360 | Phase 3 | Belarus;Poland;Ukraine;Bulgaria;Russian Federation;Germany;Latvia | ||
10 | EUCTR2019-003334-16-BG (EUCTR) | 11/03/2021 | 02/12/2020 | Novel budenosid suppository in addition to basic therapy with oral mesalazine compared to basic therapy alone for treatment of ulcerative colitis Novel budenosid suppository in addition to basic therapy with oral mesalazinecompared to basic thera ... | Randomised, double-blind, placebo-controlled, multicentre study to compare the efficacy and safety of novel 4 mg budesonide suppository in combination with oral mesalazine versus oral mesalazine monotherapy in patients with acute ulcerative colitis Randomised, double-blind, placebo-controlled, multicentre study to compare the efficacy and safety o ... | acute ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10066678;Term: Acute ulcerative colitis;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] acute ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10066678;Term: Acute ul ... | Product Name: Budenofalk® suppositories INN or Proposed INN: BUDESONIDE Other descriptive name: Budenofalk® suppositories (BUS) Trade Name: Salofalk 3g gastro-resistant prolonged-release granules Product Name: Salofalk 3g gastro-resistant prolonged-release granules INN or Proposed INN: MESALAZINE Product Name: Budenofalk® suppositories INN or Proposed INN: BUDESONIDE Other descriptive name: Budeno ... | Dr. Falk Pharma GmbH | NULL | Not Recruiting | Female: yes Male: yes | 360 | Phase 3 | Belarus;Poland;Ukraine;Russian Federation;Bulgaria;Germany;Latvia |