DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬	D00537 💬	Topiramate	[5] 6 , 140, 144, 156, 193 💬
2	Adrenergic signaling in cardiomyocytes 💬	[1] KCNQ1 💬	D09569 💬	Ezogabine	[2] 2 , 144 💬
3	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D00354 💬	Lamotrigine	[5] 13, 34, 38, 114, 144 💬
4	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D05775 💬	Rufinamide	[1] 144 💬
5	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	[5] 6 , 140, 144, 156, 193 💬
6	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	[5] 6 , 140, 144, 156, 193 💬
7	Amphetamine addiction 💬	[6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	[5] 6 , 140, 144, 156, 193 💬
8	Amphetamine addiction 💬	[4] GRIA1, GRIA2, GRIA3, GRIA4 💬	D08964 💬	Perampanel	[3] 2 , 6 , 144 💬
9	Amyotrophic lateral sclerosis 💬	[2] GRIA1, GRIA2 💬	D08964 💬	Perampanel	[3] 2 , 6 , 144 💬
10	Amyotrophic lateral sclerosis 💬	[2] GRIA1, GRIA2 💬	D00537 💬	Topiramate	[5] 6 , 140, 144, 156, 193 💬

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