Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Dextromethorphan
(Synonym: Dextromethorphan hydrobromide)		1件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide)3件: D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2Dextromethorphan 30 mg
(Synonym: Dextromethorphan hydrobromide)		1件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide)3件: D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 96, 97
3Dextromethorphan and Caffeine
(Synonym: Dextromethorphan hydrobromide)		2件: Caffeine,
Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide)		5件: D00528 ,
D00848 (Name: Dextromethorphan hydrobromide),
D01453 ,
D03742 ,
D03744 		17件: ADORA1,
ADORA2A,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A,
SIGMAR1 💬		37件: Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Huntington disease, Insulin signaling pathway, Long-term potentiation, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 78
4Dextromethorphan HBr and quinidine sulfate
(Synonym: Dextromethorphan hydrobromide)		3件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide),
Quinidine,
Sulfate ion		7件: D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		11件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		22件: Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬1件: 2
5DEXTROMETHORPHAN HYDROBROMIDE1件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide)3件: D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 13, 46
6Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg3件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide),
Quinidine,
Sulfate ion		7件: D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		11件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		22件: Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬2件: 2, 13
7Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg3件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide),
Quinidine,
Sulfate ion		7件: D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		11件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		22件: Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬2件: 2, 13
8Dextromethorphan/Quinidine
(Synonym: Dextromethorphan hydrobromide)		2件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide),
Quinidine		7件: D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		11件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		22件: Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬1件: 13
9Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)
(Synonym: Dextromethorphan hydrobromide)		2件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide),
Quinidine		7件: D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		11件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		22件: Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬1件: 8
10Dimebon + Dextromethorphan
(Synonym: Dextromethorphan hydrobromide)		2件: Dextromethorphan (Synonym: Promethazine Hydrochloride and Dextromethorphan Hydrobromide),
Latrepirdine		4件: D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 ,
D09917 		7件: ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		22件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬1件: 8