KEGG DRUG

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No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC	-	-	-	-	1件: 299
2	100 mg ELX /50 mg TEZ /75 mg IVA FDC	-	-	-	-	1件: 299
3	100 mg ELX/50 mg TEZ /75 mg IVA FDC	-	-	-	-	1件: 299
4	100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination	-	-	-	-	1件: 299
5	100 mg TEZ/150 mg IVA FDC	-	-	-	-	1件: 299
6	100 mg VX-445 /50 mg TEZ/75 mg IVA FDC	-	-	-	-	1件: 299
7	100 mg VX-445/50 mg TEZ /75 mg IVA FDC	-	-	-	-	1件: 299
8	100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC	-	-	-	-	1件: 299
9	100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC	-	-	-	-	1件: 299
10	100-mg ELX / 50-mg TEZ / 75 -mg	-	-	-	-	1件: 299
11	100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC	-	-	-	-	1件: 299
12	100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC	-	-	-	-	1件: 299
13	100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC	-	-	-	-	1件: 299
14	100-mg VX-445 /50-mg TEZ/75-mg	-	-	-	-	1件: 299
15	100-mg VX-445/50-mg TEZ/75-mg IVA FDC	-	-	-	-	1件: 299
16	100g ELX / 50mg TEZ / 75mg IVA	-	-	-	-	1件: 299
17	100mg ELX/50mg TEZ /75mg IVA	-	-	-	-	1件: 299
18	100mg VX-445/50mg TEZ /75mg IVA FDC	-	-	-	-	1件: 299
19	50 mg ELX/25 mg TEZ/37.5 mg IVA	-	-	-	-	1件: 299
20	50 mg ELX/25 mg TEZ/37.5 mg IVA fixed dose combination	-	-	-	-	1件: 299
21	80mg ELX / 40mg TEZ / 60mg IVA	-	-	-	-	1件: 299
22	Elexacaftor-tezacaftor-ivacaftor exposure	3件: Elexacaftor, Ivacaftor, Tezacaftor	3件: D09916 , D11041 (Name: Tezacaftor), D11507	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
23	Elexacaftor/tezacaftor/ivacaftor	3件: Elexacaftor, Ivacaftor, Tezacaftor	3件: D09916 , D11041 (Name: Tezacaftor), D11507	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
24	ELX (VX-445)/TEZ (VX-661)/IVA (VX-770)	-	-	-	-	1件: 299
25	ELX/TEZ/IVA	-	-	-	-	1件: 299
26	Ivacaftor or elexacaftor/tezacaftor/ivacaftor	3件: Elexacaftor, Ivacaftor, Tezacaftor	3件: D09916 , D11041 (Name: Tezacaftor), D11507	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
27	TEZ	-	-	-	-	1件: 299
28	TEZ/IVA	-	-	-	-	1件: 299
29	TEZACAFTOR	1件: Tezacaftor	1件: D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
30	Tezacaftor (TEZ)	1件: Tezacaftor	1件: D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
31	Tezacaftor/Ivacaftor	2件: Ivacaftor, Tezacaftor	2件: D09916 , D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
32	Tezacaftor/Ivacaftor + Ivacaftor	2件: Ivacaftor, Tezacaftor	2件: D09916 , D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
33	Tezacaftor/Ivacaftor 100mg/150mg	2件: Ivacaftor, Tezacaftor	2件: D09916 , D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
34	Tezacaftor/Ivacaftor/100mg/150mg	2件: Ivacaftor, Tezacaftor	2件: D09916 , D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
35	Tezosentan	1件: Tezosentan	-	-	-	1件: 86
36	Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor	4件: Elexacaftor, Ivacaftor, Lumacaftor, Tezacaftor	4件: D09916 , D10134 , D11041 (Name: Tezacaftor), D11507	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
37	VX-121/TEZ/D-IVA	-	-	-	-	1件: 299
38	VX-121/tezacaftor/deutivacaftor	2件: Deutivacaftor, Tezacaftor	2件: D11041 (Name: Tezacaftor), D11423	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
39	VX-445 / TEZ / IVA	-	-	-	-	1件: 299
40	VX-445 / TEZ / IVA FDC	-	-	-	-	1件: 299
41	VX-445 /TEZ/IVA	-	-	-	-	1件: 299
42	VX-445/TEZ/IVA	-	-	-	-	1件: 299
43	VX-659/ TEZ/IVA	1件: VX-659	-	-	-	1件: 299
44	VX-659/TEZ/IVA	1件: VX-659	-	-	-	1件: 299
45	VX-659/Tezacaftor/Ivacaftor	3件: Ivacaftor, Tezacaftor, VX-659	2件: D09916 , D11041 (Name: Tezacaftor)	1件: CFTR 💬	8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	1件: 299
46	VX-661/VX-770 (TEZ/IVA)	-	-	-	-	1件: 299