Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Dimetapp Oral Infant Cold and Fever Drops)		5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Allantoin
(Synonym: Optrex Eye Drops)		1件: ALLANTOIN1件: D00121 --1件: 36
3 alpha-Tocopherol acetate
(Synonym: Vigo Multivitamins Drops/lozenge)		3件: Tocopherol acetate; TOCOPHERYL ACETATE; Vitamin E---2件: 49, 206
4 Amoxicillin
(Synonym: Amoxil Pediatric Drops Pws 50mg/ml)		4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin3件: D00229 ,
D02925 ,
D07452 		--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
5 Ascorbic acid
(Synonym: Multivitamin Drops with Fluoride)		4件: Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
6 Betamethasone
(Synonym: Betnesol Eye and Ear Drops)		1件: Betamethasone7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
7 Biotin
(Synonym: Quflora FE Pediatric Drops)		4件: Biotin; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
8 Brimonidine
(Synonym: LUMIFY Redness Reliever Eye Drops)		2件: Brimonidine; Brimonidine tartrate2件: D02076 ,
D07540 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90
9 Caffeine
(Synonym: SMITH BROS WILD CHERRY DAY TIME with Caffeine Soothing Drops)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
10 Carboxymethylcellulose
(Synonym: Walgreen Sterile Lubricant Drops 70 Count)		1件: Carboxymethylcellulose1件: D07622 --2件: 35, 162
11 Chlorpheniramine
(Synonym: Dallergy DROPS)		1件: Clorfenamina4件: D00665 ,
D00668 ,
D07398 ,
D07803 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
12 Chlorpromazine
(Synonym: Largactil Drops 40mg/ml)		2件: Chlorpromazine; Chlorpromazine Hydrochloride4件: D00270 ,
D00789 ,
D03274 ,
D04034 		13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
13 Cholecalciferol
(Synonym: Sodium Fluoride and Vitamin D Drops)		5件: CHOLECALCIFEROL; Colecalciferol; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬25件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
14 Cromoglicic acid
(Synonym: Cromolyn Eye Drops)		4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium2件: D00526 ,
D07753 		--3件: 2, 85, 98
15 Cyanocobalamin
(Synonym: Multivitamin Drops with Fluoride)		2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
16 Dextran
(Synonym: Premier Value Sterile Eye Drops)		1件: Dextran1件: D00060 --5件: 2, 62, 79, 96, 97
17 Dextromethorphan
(Synonym: TRISPEC PSE Pediatric Drops Cough Suppressant Expectorant Nasal Decongestant GRAPE Flavor)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
18 Dorzolamide
(Synonym: Dorzolamide and Timolol Eye Drops BP)		1件: Dorzolamide2件: D00653 ,
D07871 		13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
19 Ergocalciferol
(Synonym: Aquasol A & D Drops)		3件: Ergocalciferol; Vitamin D; Vitamin D21件: D00187 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬6件: 46, 49, 84, 96, 97, 299
20 Erythromycin
(Synonym: EryPed Drops)		1件: Erythromycin9件: D00140 ,
D00851 ,
D01361 ,
D02009 ,
D02184 ,
D02523 ,
D02524 ,
D02525 ,
D04054 		--5件: 6, 36, 164, 228, 291
21 Ethanol
(Synonym: Clean Drops Hand sanitizer)		3件: Alcohol; Ethanol; PREDNISONE4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--7件: 13, 51, 58, 97, 279, 280, 298
22 Ferrous sulfate anhydrous
(Synonym: Quflora FE Pediatric Drops)		0件: ---1件: 46
23 Fluocinolone acetonide
(Synonym: Dermotic Oil Ear Drops)		2件: Fluocinolone Acetonide; Iluvien1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
24 Folic acid
(Synonym: Vigo Multivitamins Drops/lozenge)		5件: Acide folique; Folate; Folic Acid; Multivitamin; Nicotinamide1件: D00070 --6件: 6, 13, 41, 46, 49, 84
25 Glycerin
(Synonym: Exchange Select Artificial Tears Lubricant Eye Drops)		3件: Bee venom; Glycerine; Glycerol1件: D00028 --6件: 6, 13, 79, 265, 316, 317
26 Hyaluronic acid
(Synonym: Lubricant Eye Drops)		3件: Hyaluronan; Hyaluronate; Hyaluronic acid1件: D08043 --7件: 46, 53, 70, 97, 226, 231, 299
27 Hydrocortisone
(Synonym: Oticin HC Ear Drops)		6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
28 Hydrocortisone acetate
(Synonym: Neo-cortef Eye Ear Drops Sterile Suspension)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
29 Ibuprofen
(Synonym: Advil Pediatric Drops)		2件: IBUPROFEN; IBUPROFEN 200MG4件: D00126 ,
D01122 ,
D04490 ,
D06606 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
30 Iron
(Synonym: Multi-Vitamin Fluoride and Iron Drops)		1件: Iron---6件: 18, 96, 97, 238, 254, 284
31 Levomefolic acid
(Synonym: Quflora FE Pediatric Drops)		1件: L-methylfolate1件: D09353 --1件: 6
32 Lidocaine
(Synonym: Lidosporin Ear Drops)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine3件: D00358 ,
D02086 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
33 Magnesium oxide
(Synonym: Quflora Pediatric Drops)		1件: Magnesium oxide1件: D01167 --3件: 6, 166, 291
34 Mineral oil
(Synonym: Walgreens Lubricant Eye Drops Preservative Free)		1件: Paraffin Oil1件: D05042 --1件: 291
35 Morphine
(Synonym: Statex Drops 20mg/ml)		2件: Morphine; Morphine Sulfate3件: D00842 ,
D02271 ,
D08233 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬6件: 36, 46, 70, 85, 86, 298
36 Neomycin
(Synonym: Neo-cortef Eye Ear Drops Sterile Suspension)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
37 Niacin
(Synonym: Multi-Vitamin Fluoride Drops)		2件: Niacin; Nicotinic acid1件: D00049 --4件: 6, 78, 79, 265
38 Nicotinamide
(Synonym: Poly-VI-sol Drops)		4件: Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
39 Pectin
(Synonym: Ludens Blue Raspberry Throat Drops)		1件: Pectin1件: D02316 --1件: 96
40 Phenylephrine
(Synonym: EndaCof Drops)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
41 Propylene glycol
(Synonym: Walgreens Lubricant Eye Drops Dry Eye 15mL and twin pack)		1件: Propylene glycol1件: D00078 --2件: 28, 51
42 Pseudoephedrine
(Synonym: Abanatuss Ped Drops)		1件: Pseudoephedrine4件: D00485 ,
D05648 ,
D05649 ,
D08449 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
43 Pyridoxine
(Synonym: MultiVitamin with Fluoride Drops)		2件: PYRIDOXINE; Vitamin B62件: D02179 ,
D08454 		--5件: 6, 93, 145, 206, 320
44 Riboflavin
(Synonym: Quflora FE Pediatric Drops)		2件: Riboflavin; Vitamin B23件: D00050 ,
D01622 ,
D01913 		--8件: 13, 38, 46, 96, 97, 162, 168, 265
45 Salicylic acid
(Synonym: ClearSkinDays Acne Clearing Drops)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
46 Simethicone
(Synonym: Little Tummys Gas Relief Drops)		1件: Simethicone1件: D05841 --2件: 13, 96
47 Sodium fluoride
(Synonym: Multi-Vitamin Drops with Fluoride and Iron)		2件: Beam; Sodium fluoride1件: D00943 --1件: 51
48 Thiamine
(Synonym: Infant Multivitamin Drops)		2件: Thiamine; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
49 Timolol
(Synonym: Dorzolamide and Timolol Eye Drops BP)		2件: Timolol; TIMOLOL MALEATE3件: D00378 ,
D00603 ,
D08600 		2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227
50 Tocopherol
(Synonym: Multivitamin Drops with Fluoride)		2件: Tocoferol; TOCOPHEROL1件: D02332 --6件: 13, 49, 90, 206, 257, 298
51 Vitamin A
(Synonym: Multi Vitamin Drops with Fluoride and Iron)		1件: Vitamin A2件: D00069 ,
D06543 		2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
52 Vitamin D
(Synonym: NovaFerrum Multivitamin with Iron Pediatric Drops)		3件: Calciferol; Cod liver oil; Vitamin D---24件: 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
53 Vitamin E
(Synonym: NovaFerrum Multivitamin with Iron Pediatric Drops)		2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317