Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Acetaminophen 325 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)		5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Adenine
(Synonym: TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose Red Cell Preservative)		1件: Adenin1件: D00034 --1件: 46
3 Adenosine phosphate 0件: 1件: D02769 (Name: Adenosine phosphate)4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 46
4 Aluminium phosphate 1件: Aluminium phosphate---1件: 46
5 Betamethasone
(Synonym: Betamethasone Sodium Phosphate and Betamethasone Acetate)		1件: Betamethasone7件: D00244 ,
D00972 (Name: Betamethasone sodium phosphate),
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
6 Caffeine
(Synonym: Acetaminophen 500 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
7 Carvedilol
(Synonym: Carvedilol Phosphate)		1件: Carvedilol2件: D00255 ,
D03415 (Name: Carvedilol phosphate)		5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 57, 86, 113, 210
8 Chloroquine
(Synonym: Chloroquine Phosphate)		1件: Chloroquine3件: D02125 (Name: Chloroquine phosphate),
D02366 ,
D03469 		--3件: 46, 49, 95
9 Cipaglucosidase alfa
(Synonym: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate)		1件: Cipaglucosidase Alfa1件: D11798 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
10 Citric acid
(Synonym: Anticoagulant Solution Citrate Phosphate Dextrose)		1件: Citric acid2件: D00037 ,
D01222 		--2件: 53, 291
11 Clindamycin
(Synonym: Clindamycin Phosphate and Benzoyl Peroxide)		2件: CLINDAMYCIN; Dalacin C phosphate4件: D00277 ,
D01073 (Name: Clindamycin phosphate),
D01990 ,
D02132 		--2件: 46, 299
12 D-glucose
(Synonym: Anticoagulant Citrate Phosphate Dextrose Blood-Pack Units in PL 146 Plastic)		2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
13 Dexamethasone
(Synonym: Dexamethasone Sodium Phosphate)		5件: Decadron; Dexametasona; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE; Maxidex9件: D00292 ,
D00975 (Name: Dexamethasone sodium phosphate),
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
14 Dextrose, unspecified form
(Synonym: Anticoagulant Solution Citrate Phosphate Dextrose)		2件: Dextrose; Glucose---19件: 2, 6, 13, 49, 50, 56, 60, 65, 70, 75, 86, 88, 96, 160, 195, 226, 254, 257, 299
15 Dihydrocodeine 0件: 2件: D01481 (Name: Dihydrocodeine phosphate),
D07831 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 310
16 Etoposide 1件: Etoposide2件: D00125 ,
D04107 (Name: Etoposide phosphate)		2件: TOP2A,
TOP2B 💬		1件: Platinum drug resistance 💬11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331
17 Fludarabine
(Synonym: Fludarabine Phosphate Injection)		4件: FLUDARA; FLUDARABINA; Fludarabine; Fludarabine Phosphate2件: D01907 (Name: Fludarabine phosphate),
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
18 Histamine
(Synonym: Histamine Phosphate Injection USP Liq Sc)		1件: Histamine1件: D08040 4件: HRH1,
HRH2,
HRH3,
HRH4 💬		4件: Calcium signaling pathway, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 13
19 Levomefolic acid
(Synonym: Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal)		1件: L-methylfolate1件: D09353 --1件: 6
20 Mannitol
(Synonym: TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose Red Cell Preservative)		4件: Aridol; Bronchitol; Mannite; Mannitol1件: D00062 --7件: 6, 13, 28, 60, 96, 113, 299
21 Mecobalamin
(Synonym: Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal)		2件: Mecobalamin; Methylcobalamin1件: D03246 --2件: 2, 70
22 Menadiol diphosphate
(Synonym: Menadiol phosphate)		1件: Menadiol Diphosphate1件: D08176 --1件: 299
23 Metformin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)		5件: Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; METFORMINA; Metformine2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
24 Methylprednisolone 4件: Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 (Name: Methylprednisolone sodium phosphate),
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
25 Metronidazole 3件: Flagyl; Metronidazol; Metronidazole3件: D00409 ,
D05016 ,
D05017 (Name: Metronidazole phosphate)		--8件: 46, 51, 63, 94, 95, 96, 97, 291
26 Oseltamivir
(Synonym: Oseltamivir Phosphate for Oral Suspension)		1件: Oseltamivir2件: D00900 (Name: Oseltamivir phosphate),
D08306 		--2件: 97, 299
27 Phenylephrine
(Synonym: Promethazine Hydrochloride Phenylephrine Hydrochloride and Codeine Phosphate)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
28 Phosphate ion 1件: Phosphate---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
29 Phosphorus P-32
(Synonym: P32 Sodium Phosphate)		0件: ---1件: 37
30 Piperazine 1件: Piperazine6件: D00807 ,
D01393 (Name: Piperazine phosphate),
D02127 ,
D02145 ,
D05486 ,
D06224 		--2件: 58, 272
31 Prednisolone 3件: Prednisolona; PREDNISOLONE; Prednisolonum8件: D00472 ,
D00980 ,
D00981 (Name: Prednisolone sodium phosphate),
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬43件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
32 Promethazine
(Synonym: Promethazine HCl and Codeine Phosphate)		1件: Promethazine4件: D00480 ,
D00494 ,
D01242 ,
D03290 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 96
33 Pseudoephedrine
(Synonym: Codeine Phosphate and Pseudoephedrine Hydrochloride)		1件: Pseudoephedrine4件: D00485 ,
D05648 ,
D05649 ,
D08449 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
34 Pyridoxal phosphate 0件: 1件: D00006 (Name: Pyridoxal phosphate hydrate)--1件: 13
35 Riboflavin
(Synonym: Riboflavin 5 Phosphate Cap 50mg)		2件: Riboflavin; Vitamin B23件: D00050 ,
D01622 (Name: Riboflavin sodium phosphate),
D01913 		--8件: 13, 38, 46, 96, 97, 162, 168, 265
36 Sitagliptin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)		1件: Sitagliptin1件: D08516 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
37 Sodium chloride
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; SODIUM CHLORIDE; Sporanox1件: D02056 --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
38 Sodium citrate
(Synonym: Anticoagulant Solution Citrate Phosphate Dextrose)		1件: Sodium citrate2件: D01781 ,
D05855 		--4件: 67, 214, 215, 235
39 Sodium fluoride
(Synonym: Acidulated Phosphate Fluoride Oral Solution)		2件: Beam; Sodium fluoride1件: D00943 --1件: 51
40 Sodium glycerophosphate
(Synonym: Disodium glycerol phosphate)		1件: Smofkabiven1件: D10489 --1件: 66
41 Tretinoin
(Synonym: Clindamycin Phosphate and Tretinion)		5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
42 Triamcinolone 4件: Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE5件: D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 (Name: Triamcinolone acetonide sodium phosphate)		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 35, 46, 56, 70, 90, 96, 107, 162, 226, 298