Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MASP2 [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11531 Narsoplimab [4] 64, 66, 109, 222
2 CFD [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11641 Danicopan [2] 62, 222
3 F2 [8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D06410 Thrombomodulin Alfa [1] 85
4 F2 [8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D07144 Dabigatran etexilate [1] 51
5 F2 [8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D09707 Dabigatran [4] 51, 85, 91, 124
6 F8 [1] Complement and coagulation cascades D00291 Desmopressin [6] 6, 64, 72, 75, 225, 288
7 F8 [1] Complement and coagulation cascades D02235 Desmopressin [6] 6, 64, 72, 75, 225, 288
8 F9 [1] Complement and coagulation cascades D10821 Emicizumab [1] 288
9 F10 [1] Complement and coagulation cascades D03213 Apixaban [3] 96, 97, 222
10 F10 [1] Complement and coagulation cascades D07086 Rivaroxaban [5] 46, 49, 75, 91, 210
11 F10 [1] Complement and coagulation cascades D09710 Edoxaban [2] 46, 88
12 F10 [1] Complement and coagulation cascades D10821 Emicizumab [1] 288
13 SERPIND1 [1] Complement and coagulation cascades D08547 Sulodexide [4] 13, 51, 271, 288
14 KLKB1 [1] Complement and coagulation cascades D10845 Conestat alfa [1] 61
15 SERPINC1 [1] Complement and coagulation cascades D03674 Enoxaparin [1] 46
16 SERPINC1 [1] Complement and coagulation cascades D07510 Heparin [12] 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317
17 SERPINC1 [1] Complement and coagulation cascades D07510 Enoxaparin [1] 46
18 SERPINC1 [1] Complement and coagulation cascades D07510 Parnaparin [1] 97
19 SERPINC1 [1] Complement and coagulation cascades D08547 Sulodexide [4] 13, 51, 271, 288
20 PLG [4] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D00160 Aminocaproic acid [1] 70
21 PLG [4] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D01136 Tranexamic acid [6] 46, 70, 215, 227, 288, 299
22 CFB [3] Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D12251 Iptacopan [5] 61, 62, 66, 109, 222
23 C1R [6] Phagosome, Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa [1] 61
24 C1S [5] Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa [1] 61
25 C1S [5] Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11530 Sutimlimab [1] 61
26 C3 [15] Neuroactive ligand-receptor interaction, Phagosome, Complement and coagulation cascades, Neutrophil extracellular trap formation, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan [3] 2, 62, 222
27 C5 [9] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D03940 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222
28 C5 [9] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11054 Ravulizumab [7] 2, 11, 13, 50, 62, 66, 109
29 C5 [9] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11473 Nomacopan [3] 62, 109, 162
30 C5 [9] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11477 Pozelimab [2] 11, 62
31 C5 [9] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11696 Crovalimab [2] 62, 109
32 C5 [9] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11838 Vilobelimab [3] 43, 44, 269
33 C5AR1 [5] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11093 Avacopan [3] 43, 44, 222
34 VWF [8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Complement and coagulation cascades, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection, Coronavirus disease - COVID-19 D11160 Caplacizumab [1] 64