Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D09916 Ivacaftor [1] 299
2 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D10134 Lumacaftor [1] 299
3 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11041 Tezacaftor [1] 299
4 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11423 Deutivacaftor [1] 299
5 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11507 Elexacaftor [1] 299
6 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11724 Galicaftor [1] 299
7 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00113 Atropine [2] 2, 299
8 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine [1] 2
9 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
10 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide [3] 6, 13, 19
11 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin [3] 6, 13, 53
12 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00481 Propantheline [1] 26
13 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00525 Pilocarpine [3] 6, 53, 299
14 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00646 Tolterodine [2] 17, 53
15 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00661 Cevimeline [1] 53
16 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00722 Oxybutynin [3] 6, 13, 53
17 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00765 Rocuronium [1] 296
18 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00787 Trihexyphenidyl [2] 5, 6
19 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00789 Chlorpromazine [1] 254
20 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01000 Bethanechol [1] 98
21 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01077 Atropine [2] 2, 299
22 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01148 Tolterodine [2] 17, 53
23 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01269 Solifenacin [3] 6, 13, 53
24 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01699 Darifenacin [2] 6, 13
25 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D02069 Atropine [2] 2, 299
26 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D02200 Pilocarpine [3] 6, 53, 299
27 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D02212 Ipratropium [2] 6, 86
28 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03011 Atropine [2] 2, 299
29 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03274 Chlorpromazine [1] 254
30 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03654 Darifenacin [2] 6, 13
31 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03814 Atropine [2] 2, 299
32 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D04034 Chlorpromazine [1] 254
33 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D05478 Pilocarpine [3] 6, 53, 299
34 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07226 Fesoterodine [1] 6
35 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07667 Cevimeline [1] 53
36 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
37 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08522 Solifenacin [3] 6, 13, 53
38 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl [2] 5, 6
39 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine [1] 156
40 AMY2A [3] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion D00216 Acarbose [1] 298
41 AMY2B [3] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion D00216 Acarbose [1] 298
42 KCNQ1 [3] Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D00636 Amiodarone [2] 28, 127
43 KCNQ1 [3] Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D02910 Amiodarone [2] 28, 127
44 KCNQ1 [3] Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D09569 Ezogabine [2] 2, 144
45 ATP1A1 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
46 ATP1A1 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
47 ATP1A2 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
48 ATP1A2 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
49 ATP1A3 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
50 ATP1A3 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
51 ATP1A4 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
52 ATP1A4 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
53 SLC12A2 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00247 Bumetanide [2] 6, 158
54 SLC12A2 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00331 Furosemide [1] 6
55 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
56 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00518 Diclofenamide [1] 114
57 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
58 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00653 Dorzolamide [1] 90
59 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
60 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D07871 Dorzolamide [1] 90
61 CD38 [2] Salivary secretion, Pancreatic secretion D10777 Daratumumab [5] 16, 28, 49, 63, 222
62 CD38 [2] Salivary secretion, Pancreatic secretion D11050 Isatuximab [2] 28, 61
63 CD38 [2] Salivary secretion, Pancreatic secretion D11945 Mezagitamab [1] 66