Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00109	Acetylsalicylic acid	[15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
2	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00118	Naproxen	[4] 13, 46, 107, 271
3	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00120	Sulindac	[1] 206
4	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00126	Ibuprofen	[7] 13, 46, 65, 107, 113, 271, 299
5	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00132	Ketoprofen	[1] 46
6	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00141	Indomethacin	[3] 225, 271, 298
7	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00217	Acetaminophen	[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
8	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00330	Flurbiprofen	[3] 13, 21, 46
9	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00428	Salsalate	[1] 5
10	PTGS1	[5] Arachidonic acid metabolism, Metabolic pathways, Platelet activation, Serotonergic synapse, Regu ...	D00813	Ketorolac	[2] 70, 226

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