Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CSF1 [4] Ras signaling pathway, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Rheumatoid arthritis D06402 Sunitinib [2] 28, 34
2 CSF1 [4] Ras signaling pathway, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Rheumatoid arthritis D08552 Sunitinib [2] 28, 34
3 CSF1R [3] Ras signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Transcriptional misregulation in cancer D11270 Pexidartinib [1] 34
4 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D01977 Gefitinib [1] 75
5 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D03455 Cetuximab [5] 34, 51, 86, 89, 331
6 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04023 Erlotinib [1] 94
7 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04024 Lapatinib [3] 34, 74, 75
8 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D07907 Erlotinib [1] 94
9 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D08108 Lapatinib [3] 34, 74, 75
10 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11251 Icotinib [1] 34
11 EGFR [4] Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11772 Tesevatinib [1] 67
12 EPHA2 [1] Ras signaling pathway D03658 Dasatinib [2] 51, 85
13 EPHA2 [1] Ras signaling pathway D06414 Dasatinib [2] 51, 85
14 FGFR1 [4] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
15 FGFR1 [4] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D11589 Infigratinib [1] 276
16 FGFR3 [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
17 FGFR3 [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib [1] 276
18 FGFR2 [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D05338 Palifermin [5] 13, 36, 38, 39, 65
19 FGFR2 [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
20 FGFR2 [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib [1] 276
21 FLT1 [3] Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D03218 Axitinib [1] 34
22 FLT1 [3] Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D06402 Sunitinib [2] 28, 34
23 FLT1 [3] Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D08552 Sunitinib [2] 28, 34
24 FLT1 [3] Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D08881 Cediranib [1] 34
25 FLT1 [3] Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D10481 Nintedanib [5] 51, 85, 89, 227, 228
26 FLT3 [2] Ras signaling pathway, Transcriptional misregulation in cancer D06272 Sorafenib [2] 34, 86
27 FLT3 [2] Ras signaling pathway, Transcriptional misregulation in cancer D06402 Sunitinib [2] 28, 34
28 FLT3 [2] Ras signaling pathway, Transcriptional misregulation in cancer D08524 Sorafenib [2] 34, 86
29 FLT3 [2] Ras signaling pathway, Transcriptional misregulation in cancer D08552 Sunitinib [2] 28, 34
30 FLT3 [2] Ras signaling pathway, Transcriptional misregulation in cancer D11270 Pexidartinib [1] 34
31 FLT4 [1] Ras signaling pathway D03218 Axitinib [1] 34
32 FLT4 [1] Ras signaling pathway D06272 Sorafenib [2] 34, 86
33 FLT4 [1] Ras signaling pathway D06402 Sunitinib [2] 28, 34
34 FLT4 [1] Ras signaling pathway D08524 Sorafenib [2] 34, 86
35 FLT4 [1] Ras signaling pathway D08552 Sunitinib [2] 28, 34
36 FLT4 [1] Ras signaling pathway D08881 Cediranib [1] 34
37 FLT4 [1] Ras signaling pathway D10481 Nintedanib [5] 51, 85, 89, 227, 228
38 FLT4 [1] Ras signaling pathway D11772 Tesevatinib [1] 67
39 ABL1 [2] Ras signaling pathway, Viral myocarditis D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
40 ABL1 [2] Ras signaling pathway, Viral myocarditis D03252 Bosutinib [2] 2, 67
41 ABL1 [2] Ras signaling pathway, Viral myocarditis D03658 Dasatinib [2] 51, 85
42 ABL1 [2] Ras signaling pathway, Viral myocarditis D06414 Dasatinib [2] 51, 85
43 ABL1 [2] Ras signaling pathway, Viral myocarditis D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
44 ABL1 [2] Ras signaling pathway, Viral myocarditis D08953 Nilotinib [5] 6, 8, 34, 51, 86
45 ABL1 [2] Ras signaling pathway, Viral myocarditis D09664 Saracatinib [3] 6, 89, 272
46 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D00711 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
47 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
48 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D00777 Amantadine [4] 6, 8, 13, 127
49 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D00848 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
50 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D02780 Acamprosate [2] 6, 206
51 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
52 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D03744 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
53 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D04905 Memantine [7] 2, 6, 8, 13, 49, 127, 205
54 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D07058 Acamprosate [2] 6, 206
55 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D07283 Esketamine [3] 2, 4, 70
56 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D07441 Amantadine [4] 6, 8, 13, 127
57 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
58 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D08174 Memantine [7] 2, 6, 8, 13, 49, 127, 205
59 GRIN1 [2] Ras signaling pathway, Spinocerebellar ataxia D09917 Latrepirdine [1] 8
60 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00711 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
61 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
62 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00777 Amantadine [4] 6, 8, 13, 127
63 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00848 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
64 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D02780 Acamprosate [2] 6, 206
65 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
66 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03744 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
67 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D04905 Memantine [7] 2, 6, 8, 13, 49, 127, 205
68 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
69 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
70 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
71 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
72 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine [7] 2, 6, 8, 13, 49, 127, 205
73 GRIN2A [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine [1] 8
74 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00711 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
75 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
76 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00777 Amantadine [4] 6, 8, 13, 127
77 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00848 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
78 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D02780 Acamprosate [2] 6, 206
79 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
80 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03744 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
81 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D04905 Memantine [7] 2, 6, 8, 13, 49, 127, 205
82 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
83 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
84 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
85 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
86 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine [7] 2, 6, 8, 13, 49, 127, 205
87 GRIN2B [3] Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine [1] 8
88 IGF1R [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D03297 Mecasermin [6] 65, 78, 96, 168, 265, 299
89 IGF1R [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D04870 Mecasermin [6] 65, 78, 96, 168, 265, 299
90 IGF1R [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09680 Teprotumumab [1] 51
91 IGF1R [3] Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09925 Linsitinib [1] 232
92 INSR [3] Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D00085 Insulin human [2] 96, 156
93 INSR [3] Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03230 Insulin human [2] 96, 156
94 INSR [3] Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03250 Insulin glargine [1] 299
95 INSR [3] Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D04539 Insulin detemir [1] 299
96 KDR [2] Ras signaling pathway, VEGF signaling pathway D03218 Axitinib [1] 34
97 KDR [2] Ras signaling pathway, VEGF signaling pathway D06272 Sorafenib [2] 34, 86
98 KDR [2] Ras signaling pathway, VEGF signaling pathway D06402 Sunitinib [2] 28, 34
99 KDR [2] Ras signaling pathway, VEGF signaling pathway D08524 Sorafenib [2] 34, 86
100 KDR [2] Ras signaling pathway, VEGF signaling pathway D08552 Sunitinib [2] 28, 34
101 KDR [2] Ras signaling pathway, VEGF signaling pathway D08881 Cediranib [1] 34
102 KDR [2] Ras signaling pathway, VEGF signaling pathway D10062 Cabozantinib [1] 34
103 KDR [2] Ras signaling pathway, VEGF signaling pathway D10481 Nintedanib [5] 51, 85, 89, 227, 228
104 KDR [2] Ras signaling pathway, VEGF signaling pathway D11772 Tesevatinib [1] 67
105 KIT [1] Ras signaling pathway D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
106 KIT [1] Ras signaling pathway D03658 Dasatinib [2] 51, 85
107 KIT [1] Ras signaling pathway D06272 Sorafenib [2] 34, 86
108 KIT [1] Ras signaling pathway D06402 Sunitinib [2] 28, 34
109 KIT [1] Ras signaling pathway D06414 Dasatinib [2] 51, 85
110 KIT [1] Ras signaling pathway D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
111 KIT [1] Ras signaling pathway D08524 Sorafenib [2] 34, 86
112 KIT [1] Ras signaling pathway D08552 Sunitinib [2] 28, 34
113 KIT [1] Ras signaling pathway D08953 Nilotinib [5] 6, 8, 34, 51, 86
114 KIT [1] Ras signaling pathway D10229 Masitinib [6] 2, 5, 6, 13, 46, 96
115 KIT [1] Ras signaling pathway D11270 Pexidartinib [1] 34
116 MET [3] Ras signaling pathway, Transcriptional misregulation in cancer, Renal cell carcinoma D10062 Cabozantinib [1] 34
117 NFKB1 [17] Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D01146 Iguratimod [4] 46, 51, 53, 271
118 NGF [1] Ras signaling pathway D09387 Tanezumab [2] 226, 298
119 NGFR [2] Ras signaling pathway, Transcriptional misregulation in cancer D11028 Cenegermin [2] 53, 90
120 PDGFRA [2] Ras signaling pathway, Regulation of actin cytoskeleton D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
121 PDGFRA [2] Ras signaling pathway, Regulation of actin cytoskeleton D06402 Sunitinib [2] 28, 34
122 PDGFRA [2] Ras signaling pathway, Regulation of actin cytoskeleton D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
123 PDGFRA [2] Ras signaling pathway, Regulation of actin cytoskeleton D08552 Sunitinib [2] 28, 34
124 PDGFRA [2] Ras signaling pathway, Regulation of actin cytoskeleton D08953 Nilotinib [5] 6, 8, 34, 51, 86
125 PDGFRA [2] Ras signaling pathway, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
126 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D03658 Dasatinib [2] 51, 85
127 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D06272 Sorafenib [2] 34, 86
128 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D06402 Sunitinib [2] 28, 34
129 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D06414 Dasatinib [2] 51, 85
130 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D08524 Sorafenib [2] 34, 86
131 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D08552 Sunitinib [2] 28, 34
132 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D08953 Nilotinib [5] 6, 8, 34, 51, 86
133 PDGFRB [2] Ras signaling pathway, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
134 PGF [1] Ras signaling pathway D09574 Aflibercept [2] 90, 166
135 PIK3CA [19] Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
136 PIK3CB [19] Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
137 PIK3CD [19] Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
138 PIK3CD [19] Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
139 MAP2K1 [16] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib [1] 34
140 MAP2K1 [16] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
141 MAP2K1 [16] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib [1] 280
142 MAP2K1 [16] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib [1] 34
143 MAP2K2 [14] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib [1] 34
144 MAP2K2 [14] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
145 MAP2K2 [14] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib [1] 280
146 MAP2K2 [14] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib [1] 34
147 RAF1 [13] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D06272 Sorafenib [2] 34, 86
148 RAF1 [13] Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D08524 Sorafenib [2] 34, 86
149 RELA [17] Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D12181 Edasalonexent [1] 113
150 VEGFA [5] Ras signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab [4] 34, 166, 227, 301
151 VEGFA [5] Ras signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab [9] 13, 34, 85, 86, 87, 89, 227, 280, 331
152 VEGFA [5] Ras signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept [2] 90, 166
153 VEGFB [2] Ras signaling pathway, Relaxin signaling pathway D09574 Aflibercept [2] 90, 166
154 FGF23 [2] Ras signaling pathway, Regulation of actin cytoskeleton D10913 Burosumab [1] 238