Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ELANE [2] Transcriptional misregulation in cancer, Systemic lupus erythematosus D03788 Sivelestat [3] 13, 85, 96
2 GRIN2A [1] Systemic lupus erythematosus D00711 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
3 GRIN2A [1] Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
4 GRIN2A [1] Systemic lupus erythematosus D00777 Amantadine [4] 6, 8, 13, 127
5 GRIN2A [1] Systemic lupus erythematosus D00848 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
6 GRIN2A [1] Systemic lupus erythematosus D02780 Acamprosate [2] 6, 206
7 GRIN2A [1] Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
8 GRIN2A [1] Systemic lupus erythematosus D03744 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
9 GRIN2A [1] Systemic lupus erythematosus D04905 Memantine [7] 2, 6, 8, 13, 49, 127, 205
10 GRIN2A [1] Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
11 GRIN2A [1] Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
12 GRIN2A [1] Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
13 GRIN2A [1] Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
14 GRIN2A [1] Systemic lupus erythematosus D08174 Memantine [7] 2, 6, 8, 13, 49, 127, 205
15 GRIN2A [1] Systemic lupus erythematosus D09917 Latrepirdine [1] 8
16 GRIN2B [1] Systemic lupus erythematosus D00711 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
17 GRIN2B [1] Systemic lupus erythematosus D00775 Riluzole [9] 2, 3, 5, 8, 13, 17, 18, 203, 206
18 GRIN2B [1] Systemic lupus erythematosus D00777 Amantadine [4] 6, 8, 13, 127
19 GRIN2B [1] Systemic lupus erythematosus D00848 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
20 GRIN2B [1] Systemic lupus erythematosus D02780 Acamprosate [2] 6, 206
21 GRIN2B [1] Systemic lupus erythematosus D03742 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
22 GRIN2B [1] Systemic lupus erythematosus D03744 Dextromethorphan [11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
23 GRIN2B [1] Systemic lupus erythematosus D04905 Memantine [7] 2, 6, 8, 13, 49, 127, 205
24 GRIN2B [1] Systemic lupus erythematosus D07058 Acamprosate [2] 6, 206
25 GRIN2B [1] Systemic lupus erythematosus D07283 Esketamine [3] 2, 4, 70
26 GRIN2B [1] Systemic lupus erythematosus D07441 Amantadine [4] 6, 8, 13, 127
27 GRIN2B [1] Systemic lupus erythematosus D08098 Ketamine [8] 2, 4, 6, 13, 70, 113, 156, 215
28 GRIN2B [1] Systemic lupus erythematosus D08174 Memantine [7] 2, 6, 8, 13, 49, 127, 205
29 GRIN2B [1] Systemic lupus erythematosus D09917 Latrepirdine [1] 8
30 HLA-DMA [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
31 HLA-DMB [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
32 HLA-DOA [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
33 HLA-DOB [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
34 HLA-DPA1 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
35 HLA-DPB1 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
36 HLA-DQA1 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
37 HLA-DQA2 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
38 HLA-DQB1 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
39 HLA-DRA [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
40 HLA-DRB1 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
41 HLA-DRB3 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
42 HLA-DRB4 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
43 HLA-DRB5 [7] Th1 and Th2 cell differentiation, Th17 cell differentiation, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus, Viral myocarditis D04318 Glatiramer [4] 2, 13, 96, 156
44 IFNG [8] TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04242 Fontolizumab [1] 46
45 IFNG [8] TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D11120 Emapalumab [2] 49, 107
46 IL10 [6] Viral protein interaction with cytokine and cytokine receptor, T cell receptor signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
47 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
48 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
49 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
50 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02597 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
51 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
52 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
53 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
54 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
55 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D05393 Pegsunercept [1] 46
56 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
57 TNF [11] Viral protein interaction with cytokine and cytokine receptor, TGF-beta signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis, Systemic lupus erythematosus D09944 Ozoralizumab [1] 46
58 C1R [1] Systemic lupus erythematosus D10845 Conestat alfa [1] 61
59 C1S [1] Systemic lupus erythematosus D10845 Conestat alfa [1] 61
60 C1S [1] Systemic lupus erythematosus D11530 Sutimlimab [1] 61
61 C3 [3] Tuberculosis, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan [3] 2, 62, 222
62 C5 [1] Systemic lupus erythematosus D03940 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222
63 C5 [1] Systemic lupus erythematosus D11054 Ravulizumab [7] 2, 11, 13, 50, 62, 66, 109
64 C5 [1] Systemic lupus erythematosus D11473 Nomacopan [3] 62, 109, 162
65 C5 [1] Systemic lupus erythematosus D11477 Pozelimab [2] 11, 62
66 C5 [1] Systemic lupus erythematosus D11696 Crovalimab [2] 62, 109
67 C5 [1] Systemic lupus erythematosus D11838 Vilobelimab [3] 43, 44, 269
68 CD80 [4] Toll-like receptor signaling pathway, Type I diabetes mellitus, Systemic lupus erythematosus, Viral myocarditis D03203 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
69 CD80 [4] Toll-like receptor signaling pathway, Type I diabetes mellitus, Systemic lupus erythematosus, Viral myocarditis D03222 Belatacept [1] 46
70 CD86 [5] Toll-like receptor signaling pathway, Type I diabetes mellitus, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D03203 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
71 CD86 [5] Toll-like receptor signaling pathway, Type I diabetes mellitus, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D03222 Belatacept [1] 46
72 CD40 [5] Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11357 Bleselumab [1] 222
73 CD40 [5] Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11597 Ravagalimab [2] 53, 97
74 CD40 [5] Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Viral myocarditis D11610 Iscalimab [2] 49, 53
75 CD40LG [4] T cell receptor signaling pathway, Toxoplasmosis, Systemic lupus erythematosus, Viral myocarditis D06193 Toralizumab [1] 63