Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Melanogenesis 💬
 [1] EDNRB 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2 Melanogenesis 💬
 [1] EDNRB 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
3 Melanogenesis 💬
 [1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
4 Melanogenesis 💬
 [1] KIT 💬 D03658 💬 Dasatinib [2] 51, 85 💬
5 Melanogenesis 💬
 [1] KIT 💬 D06414 💬 Dasatinib [2] 51, 85 💬
6 Melanogenesis 💬
 [1] KIT 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
7 Melanogenesis 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
8 Melanogenesis 💬
 [1] KIT 💬 D10229 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
9 Melanogenesis 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
10 Melanogenesis 💬
 [1] KIT 💬 D11270 💬 Pexidartinib [1] 34 💬
11 Melanogenesis 💬
 [1] KIT 💬 D06402 💬 Sunitinib [2] 28, 34 💬
12 Melanogenesis 💬
 [1] KIT 💬 D08552 💬 Sunitinib [2] 28, 34 💬
13 Melanogenesis 💬
 [2] KIT, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
14 Melanogenesis 💬
 [2] KIT, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
15 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
16 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
17 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
18 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
19 Melanogenesis 💬
 [1] MC1R 💬 D10511 💬 Afamelanotide [3] 159, 161, 254 💬