2. Amyotrophic lateral sclerosis Clinical trials / Disease details

Clinical trials : 624 / Drugs : 611 - (DrugBank : 160) / Drug target genes : 172 - Drug target pathways : 225

14 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-004040-29-PT (EUCTR)	14/01/2022	20/05/2021	A Clinical Study in which patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) will receive R ...	A Phase 3, Multi-center, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ...	Product Name: reldesemtiv Product Code: CK-2127107 INN or Proposed INN: reldesemtiv Other descriptive n ...	Cytokinetics Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	555	Phase 3	Portugal;United States;Spain;Ireland;United Kingdom;Switzerland;Italy;France;Canada;Belgium;Poland;A ...
2	EUCTR2020-004040-29-NL (EUCTR)	25/11/2021	01/09/2021	A Clinical Study in which patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) will receive R ...	A Phase 3, Multi-center, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ...	Product Name: reldesemtiv Product Code: CK-2127107 INN or Proposed INN: reldesemtiv Other descriptive n ...	Cytokinetics Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	555	Phase 3	United States;Portugal;Spain;Ireland;United Kingdom;Switzerland;Italy;France;Canada;Belgium;Poland;A ...
3	EUCTR2020-004040-29-ES (EUCTR)	05/10/2021	21/06/2021	A Clinical Study in which patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) will receive R ...	A Phase 3, Multi-center, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ...	Product Name: reldesemtiv Product Code: CK-2127107 INN or Proposed INN: reldesemtiv Other descriptive n ...	Cytokinetics Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	555	Phase 3	United States;Portugal;Spain;Ireland;United Kingdom;Switzerland;Italy;France;Canada;Belgium;Poland;A ...
4	EUCTR2020-004040-29-IT (EUCTR)	20/09/2021	30/08/2021	A Clinical Study in which patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) will receive R ...	A Phase 3, Multi-center, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ...	Product Name: reldesemtiv Product Code: [CK-2127107] INN or Proposed INN: reldesemtiv	CYTOKINETICS, INC.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	555	Phase 3	United States;Portugal;Spain;Ireland;United Kingdom;Switzerland;Italy;France;Canada;Belgium;Poland;A ...
5	EUCTR2020-004040-29-SE (EUCTR)	07/09/2021	01/06/2021	A Clinical Study in which patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) will receive R ...	A Phase 3, Multi-center, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ...	Product Name: reldesemtiv Product Code: CK-2127107 INN or Proposed INN: reldesemtiv Other descriptive n ...	Cytokinetics Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	555	Phase 3	United States;Portugal;Spain;Ireland;United Kingdom;Switzerland;Italy;France;Canada;Belgium;Poland;A ...
6	NCT04944784 (ClinicalTrials.gov)	August 16, 2021	16/6/2021	A Study to Evaluate the Efficacy and Safety of Reldesemtivin Patients With Amyotrophic Lateral Scler ...	A Phase 3, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis	Drug: Reldesemtiv;Drug: Placebo	Cytokinetics	NULL	Recruiting	18 Years	80 Years	All	555	Phase 3	United States;Australia;Belgium;Canada;France;Germany;Ireland;Italy;Netherlands;Spain;Sweden;Switzer ...
7	EUCTR2020-004040-29-IE (EUCTR)	02/07/2021	09/04/2021	A Clinical Study in which patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) will receive R ...	A Phase 3, Multi-center, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 21.1;Level: PT;Classification code 10002026;Term ...	Product Name: reldesemtiv Product Code: CK-2127107 INN or Proposed INN: reldesemtiv Other descriptive n ...	Cytokinetics Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	555	Phase 3	United States;Portugal;Spain;Ireland;United Kingdom;Switzerland;Italy;France;Canada;Belgium;Poland;A ...
8	EUCTR2018-000586-37-IE (EUCTR)	13/09/2018	08/05/2018	A Study to Evaluate the Efficacy, Safety and Tolerability of CK-2127107In Patients with Amyotrophic ...	A Phase 2, Multi-Center, Double-Blind, Randomized, Dose-Ranging, Placebo-Controlled Study to Evaluat ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ...	Product Name: Reldesemtiv Product Code: CK-2127107 INN or Proposed INN: Reldesemtiv Other descriptive n ...	Cytokinetics, Inc.	NULL	Not Recruiting			Female: yes Male: yes	445	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United States;Canada;Spain;Ireland;Australia;Netherlands
9	EUCTR2018-000586-37-NL (EUCTR)	15/08/2018	04/06/2018	A Study to Evaluate the Efficacy, Safety and Tolerability of CK-2127107In Patients with Amyotrophic ...	A Phase 2, Multi-Center, Double-Blind, Randomized, Dose-Ranging, Placebo-Controlled Study to Evaluat ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ...	Product Name: Reldesemtiv Product Code: CK-2127107 INN or Proposed INN: Reldesemtiv Other descriptive n ...	Cytokinetics, Inc.	NULL	Not Recruiting			Female: yes Male: yes	445	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United States;Canada;Spain;Ireland;Australia;Netherlands
10	EUCTR2018-000586-37-ES (EUCTR)	19/07/2018	23/05/2018	A Study to Evaluate the Efficacy, Safety and Tolerability of CK-2127107In Patients with Amyotrophic ...	A Phase 2, Multi-Center, Double-Blind, Randomized, Dose-Ranging, Placebo-Controlled Study to Evaluat ...	Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 20.0;Level: PT;Classification code 10002026;Term ...	Product Name: Reldesemtiv Product Code: CK-2127107 INN or Proposed INN: Reldesemtiv Other descriptive n ...	Cytokinetics, Inc.	NULL	Not Recruiting			Female: yes Male: yes	445	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United States;Canada;Spain;Ireland;Australia;Netherlands

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