6. Parkinson disease Clinical trials / Disease details

Clinical trials : 2,298 / Drugs : 2,202 - (DrugBank : 350) / Drug target genes : 188 - Drug target pathways : 202

6 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04287543 (ClinicalTrials.gov)	May 2021	21/2/2020	Melatonin on Clock Genes in Parkinson's Disease	Effect of MelatoninAdministration on the PER1 and BMAL1 Clock Genes in Patients With Parkinson's Dis ...	Parkinson Disease	Drug: Melatonin;Drug: Placebos	Instituto Mexicano del Seguro Social	NULL	Withdrawn	20 Years	N/A	All	0	Phase 2/Phase 3	Mexico
2	NCT02789592 (ClinicalTrials.gov)	July 2016	31/5/2016	Efficacy and Safety of MelatoninPR and Clonazepam in Patients With REM Sleep Behavior Disorder in Pa ...	A Randomized Double-Blind, Double-Dummy, Crossover Study to Evaluate the Efficacy and Safety of Prol ...	REM Sleep Behavior Disorder;Parkinson Disease	Drug: Melatonin PR;Drug: Clonazepam;Drug: Melatonin PR placebo;Drug: Clonazepam placebo	Seoul National University Hospital	Kuhnil Pharmaceutical Co., Ltd.	Not yet recruiting	30 Years	N/A	Both	30	Phase 2	Korea, Republic of
3	NCT03258294 (ClinicalTrials.gov)	January 13, 2016	20/8/2017	Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease	Effect of Melatoninon Sleep Disturbances in Patients With Parkinson's Disease: Double Blind, Randomi ...	Parkinson's Disease	Drug: Melatonin (Circadin®);Drug: Placebo Oral Tablet	KIMJisun	Kuhnil Pharmaceutical Co., Ltd.	Enrolling by invitation	55 Years	N/A	All	82	Phase 4	NULL
4	NCT02768077 (ClinicalTrials.gov)	January 2016	9/5/2016	Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease	Effect of Melatoninon Sleep Disturbances in Patients With Parkinson's Disease: Double Blind, Randomi ...	Parkinson's Disease	Drug: Melatonin (Circadin®);Drug: Placebo	Kuhnil Pharmaceutical Co., Ltd.	NULL	Enrolling by invitation	55 Years	N/A	Both	100	Phase 4	NULL
5	EUCTR2014-002697-37-GB (EUCTR)	15/04/2015	19/03/2015	Study of Melatonin for treatment of Nocturia in PD	Single-centre open label exploratory phase IIb pilot study of exogenous oral Melatoninfor the treatm ...	Parkinson's DiseaseNocturia MedDRA version: 17.1;Level: PT;Classification code 10061536;Term: Parkin ...	Trade Name: Circadin ® Product Name: Melatonin Product Code: AS2 INN or Proposed INN: Melatonin	University College London	NULL	Not Recruiting			Female: yes Male: yes	20	Phase 2	United Kingdom
6	NCT02359448 (ClinicalTrials.gov)	April 2015	4/2/2015	Melatonin for Nocturia in Parkinson's Disease	Single-centre Open Label Exploratory Phase IIb Pilot Study of Exogenous Oral Melatoninfor the Treatm ...	Parkinson's Disease;Nocturia	Drug: Melatonin	University College, London	NULL	Not yet recruiting	18 Years	N/A	Both	20	Phase 2	United Kingdom

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