Plasma exchange (PE) ( DrugBank: - )

3 diseases

ID	Disease name (Link within this page)	Number of trials
64	Thrombotic thrombocytopenic purpura	1
66	IgA nephropathy	1
220	Rapidly progressive glomerulonephritis	1

64. Thrombotic thrombocytopenic purpura

Clinical trials : 86 / Drugs : 81 - (DrugBank : 20) / Drug target genes : 16 - Drug target pathways : 63

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04074187 (ClinicalTrials.gov)	October 21, 2019	14/8/2019	A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)	An Open-label Multicenter Trial to Study the Efficacy and Safety of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura	Thrombotic Thrombocytopenic Purpura	Drug: Caplacizumab (ALX-0081);Drug: Plasma exchange (PE);Drug: Corticosteroid treatment (Methylprednisolone or prednisolone);Drug: Immunosuppressive treatment (eg, rituximab)	Sanofi	NULL	Completed	18 Years	N/A	All	21	Phase 2/Phase 3	Japan

Clinical trials : 255 / Drugs : 255 - (DrugBank : 79) / Drug target genes : 35 - Drug target pathways : 137

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02647255 (ClinicalTrials.gov)	March 2016	21/12/2015	Trial of Plasma Exchange for Severe Crescentic IgA Nephropathy	Randomized Trial of Plasma Exchange as Adjunctive Therapy for Severe Crescentic GlomerUlonephritis of IgA NEphropathy (RESCUE Study)	Glomerulonephritis, IGA;Kidney Diseases;Acute Renal Insufficiency;Rapidly Progressive Glomerulonephritis	Procedure: Plasma Exchange (PE);Drug: Methylprednisolone pulse	Peking University First Hospital	NULL	Terminated	14 Years	65 Years	All	10	Phase 2/Phase 3	China

Clinical trials : 2 / Drugs : 5 - (DrugBank : 2) / Drug target gene : 1 - Drug target pathway : 1

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02647255 (ClinicalTrials.gov)	March 2016	21/12/2015	Trial of Plasma Exchange for Severe Crescentic IgA Nephropathy	Randomized Trial of Plasma Exchange as Adjunctive Therapy for Severe Crescentic GlomerUlonephritis of IgA NEphropathy (RESCUE Study)	Glomerulonephritis, IGA;Kidney Diseases;Acute Renal Insufficiency;Rapidly Progressive Glomerulonephritis	Procedure: Plasma Exchange (PE);Drug: Methylprednisolone pulse	Peking University First Hospital	NULL	Terminated	14 Years	65 Years	All	10	Phase 2/Phase 3	China