| No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
| 1 | Apelin signaling pathway 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 2 | cAMP signaling pathway 2 genes, 1 drug (DrugBank) and 1 disease shown |
2件: PDE3A, PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 3 | cGMP-PKG signaling pathway 3 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: PDE3A, PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
| D08514 |
| 4 | Collecting duct acid secretion 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
| D01207 |
| D05259 |
| D05261 |
| 5 | Gastric acid secretion 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
| D01207 |
| D05259 |
| D05261 |
| 6 | Glucagon signaling pathway 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 7 | Insulin signaling pathway 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 8 | Metabolic pathways 5 genes, 3 drugs (DrugBank) and 23 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
| D01207 |
| D05259 |
| D05261 |
| 2件: PDE3A, PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
| D08514 |
| 9 | Morphine addiction 2 genes, 1 drug (DrugBank) and 1 disease shown |
2件: PDE3A, PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 10 | Oxidative phosphorylation 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
| D01207 |
| D05259 |
| D05261 |
| 11 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 12 | Purine metabolism 3 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: PDE3A, PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
| D08514 |
| 13 | Regulation of lipolysis in adipocytes 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |
| 14 | Renin secretion 2 genes, 1 drug (DrugBank) and 1 disease shown |
2件: PDE3A, PDE3B |
D00417 |
Milrinone |
1件: 294 |
| D02085 |