| No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
| 1 | Adherens junction 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 2 | Alcoholism 6 genes, 2 drugs (DrugBank) and 9 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 3 | Aldosterone synthesis and secretion 2 genes, 3 drugs (DrugBank) and 17 diseases shown |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
| D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
| 1件: PDE2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 4 | Alzheimer disease 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 5 | Amphetamine addiction 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 6 | AMPK signaling pathway 2 genes, 2 drugs (DrugBank) and 18 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 7 | Amyotrophic lateral sclerosis (ALS) 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 8 | Apelin signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 9 | Autophagy - animal 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 10 | Breast cancer 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 11 | Calcium signaling pathway 6 genes, 2 drugs (DrugBank) and 9 diseases shown |
2件: ADORA2A, PDE1B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 12 | cAMP signaling pathway 18 genes, 6 drugs (DrugBank) and 20 diseases shown |
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 1件: GHSR |
D10563 |
Macimorelin |
1件: 78 |
| 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
| D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
| 3件: SSTR1, SSTR2, SSTR5 |
D07431 |
Somatostatin |
2件: 67, 78 |
| 13 | cGMP-PKG signaling pathway 8 genes, 2 drugs (DrugBank) and 6 diseases shown |
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 3件: ADRA2A, ADRA2B, ADRA2C |
D00281 |
Clonidine |
2件: 6, 78 |
| D00604 |
| 14 | Cholinergic synapse 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ACHE |
D00670 |
Donepezil |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
| D07869 |
| 15 | Circadian entrainment 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 16 | Cocaine addiction 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 17 | Cortisol synthesis and secretion 1 gene, 2 drugs (DrugBank) and 14 diseases shown |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
| D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
| 18 | Cushing syndrome 3 genes, 3 drugs (DrugBank) and 14 diseases shown |
2件: CRHR1, CRHR2 |
D03905 |
Corticorelin |
2件: 75, 78 |
| 1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
| D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
| 19 | Cytokine-cytokine receptor interaction 1 gene, 5 drugs (DrugBank) and 20 diseases shown |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| D05394 |
Pegvisomant |
1件: 78 |
| D11194 |
Somapacitan |
1件: 78 |
| D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
| D11193 |
Somavaratan |
1件: 78 |
| 20 | Dopaminergic synapse 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 21 | EGFR tyrosine kinase inhibitor resistance 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 22 | Endocrine resistance 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 23 | Endocytosis 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 24 | Estrogen signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: OPRM1 |
D01355 |
Tramadol |
5件: 46, 70, 78, 226, 271 |
| D08623 |
| 25 | Focal adhesion 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 26 | FoxO signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 27 | Gastric acid secretion 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: SSTR2 |
D07431 |
Somatostatin |
2件: 67, 78 |
| 28 | Glioma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 29 | Glucagon signaling pathway 2 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: GCGR |
D00116 |
Glucagon |
1件: 78 |
| D02118 |
| 1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 30 | Glutamatergic synapse 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 31 | Glycerophospholipid metabolism 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ACHE |
D00670 |
Donepezil |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
| D07869 |
| 32 | Growth hormone synthesis, secretion and action 7 genes, 9 drugs (DrugBank) and 21 diseases shown |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| D05394 |
Pegvisomant |
1件: 78 |
| D11194 |
Somapacitan |
1件: 78 |
| D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
| D11193 |
Somavaratan |
1件: 78 |
| 1件: GHRHR |
D08523 |
Somatorelin |
2件: 13, 78 |
| D06655 |
Tesamorelin |
2件: 78, 265 |
| 1件: GHSR |
D10563 |
Macimorelin |
1件: 78 |
| 4件: SSTR1, SSTR2, SSTR3, SSTR5 |
D07431 |
Somatostatin |
2件: 67, 78 |
| 33 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 34 | HIF-1 signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 35 | Huntington disease 3 genes, 2 drugs (DrugBank) and 20 diseases shown |
2件: GRIN1, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 36 | Inflammatory mediator regulation of TRP channels 2 genes, 1 drug (DrugBank) and 1 disease shown |
2件: TRPA1, TRPM8 |
D00064 |
Levomenthol |
1件: 78 |
| 37 | Insulin signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 38 | JAK-STAT signaling pathway 1 gene, 5 drugs (DrugBank) and 20 diseases shown |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| D05394 |
Pegvisomant |
1件: 78 |
| D11194 |
Somapacitan |
1件: 78 |
| D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
| D11193 |
Somavaratan |
1件: 78 |
| 39 | Long-term depression 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: CRHR1 |
D03905 |
Corticorelin |
2件: 75, 78 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 40 | Long-term potentiation 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 41 | Longevity regulating pathway 2 genes, 2 drugs (DrugBank) and 18 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 42 | Longevity regulating pathway - multiple species 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 43 | MAPK signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 44 | Melanoma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 45 | Metabolic pathways 10 genes, 2 drugs (DrugBank) and 8 diseases shown |
1件: CYP19A1 |
D00960 |
Anastrozole |
3件: 78, 86, 193 |
| 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 46 | Morphine addiction 10 genes, 2 drugs (DrugBank) and 9 diseases shown |
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 1件: OPRM1 |
D01355 |
Tramadol |
5件: 46, 70, 78, 226, 271 |
| D08623 |
| 47 | mTOR signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 48 | Neuroactive ligand-receptor interaction 26 genes, 21 drugs (DrugBank) and 38 diseases shown |
2件: ADORA1, ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 3件: ADRA2A, ADRA2B, ADRA2C |
D00281 |
Clonidine |
2件: 6, 78 |
| D00604 |
| 2件: CRHR1, CRHR2 |
D03905 |
Corticorelin |
2件: 75, 78 |
| 1件: GCGR |
D00116 |
Glucagon |
1件: 78 |
| D02118 |
| 1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| D05394 |
Pegvisomant |
1件: 78 |
| D11194 |
Somapacitan |
1件: 78 |
| D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
| D11193 |
Somavaratan |
1件: 78 |
| 1件: GHRHR |
D08523 |
Somatorelin |
2件: 13, 78 |
| D06655 |
Tesamorelin |
2件: 78, 265 |
| 1件: GHSR |
D10563 |
Macimorelin |
1件: 78 |
| 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
| D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
| 1件: NR3C1 |
D00088 |
Hydrocortisone |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
| D00165 |
Hydrocortisone acetate |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
| 1件: OPRM1 |
D01355 |
Tramadol |
5件: 46, 70, 78, 226, 271 |
| D08623 |
| 5件: SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 |
D07431 |
Somatostatin |
2件: 67, 78 |
| 2件: THRA, THRB |
D01010 |
Levothyroxine |
2件: 49, 78 |
| D08125 |
| D01011 |
Liothyronine |
3件: 13, 78, 212 |
| D08128 |
| 49 | Nicotine addiction 5 genes, 1 drug (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 50 | Olfactory transduction 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: PDE1B, PDE2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 51 | Oocyte meiosis 2 genes, 2 drugs (DrugBank) and 11 diseases shown |
1件: AR |
D00075 |
Testosterone |
7件: 1, 2, 3, 13, 78, 113, 265 |
| D00957 |
| D00958 |
| D00959 |
| D06085 |
| D06087 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 52 | Osteoclast differentiation 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 53 | Ovarian steroidogenesis 2 genes, 2 drugs (DrugBank) and 8 diseases shown |
1件: CYP19A1 |
D00960 |
Anastrozole |
3件: 78, 86, 193 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 54 | Parathyroid hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank) and 6 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 55 | Parkinson disease 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 56 | Pathways in cancer 3 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: AR |
D00075 |
Testosterone |
7件: 1, 2, 3, 13, 78, 113, 265 |
| D00957 |
| D00958 |
| D00959 |
| D06085 |
| D06087 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 57 | PI3K-Akt signaling pathway 2 genes, 5 drugs (DrugBank) and 20 diseases shown |
1件: GHR |
D05394 |
Pegvisomant |
1件: 78 |
| D11194 |
Somapacitan |
1件: 78 |
| D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
| D11193 |
Somavaratan |
1件: 78 |
| 2件: GHR, IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 58 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 59 | Progesterone-mediated oocyte maturation 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 60 | Prostate cancer 2 genes, 2 drugs (DrugBank) and 11 diseases shown |
1件: AR |
D00075 |
Testosterone |
7件: 1, 2, 3, 13, 78, 113, 265 |
| D00957 |
| D00958 |
| D00959 |
| D06085 |
| D06087 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 61 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 62 | Purine metabolism 9 genes, 1 drug (DrugBank) and 6 diseases shown |
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 63 | Rap1 signaling pathway 5 genes, 3 drugs (DrugBank) and 13 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 64 | Ras signaling pathway 4 genes, 2 drugs (DrugBank) and 13 diseases shown |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 65 | Regulation of lipolysis in adipocytes 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: ADORA1, PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 66 | Renin secretion 4 genes, 1 drug (DrugBank) and 6 diseases shown |
4件: ADORA1, PDE1B, PDE3A, PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 67 | Serotonergic synapse 1 gene, 2 drugs (DrugBank) and 8 diseases shown |
1件: SLC6A4 |
D00809 |
Amitriptyline |
3件: 78, 226, 299 |
| D07448 |
| D00326 |
Fluoxetine |
6件: 13, 17, 78, 86, 179, 206 |
| D00823 |
| 68 | Signaling pathways regulating pluripotency of stem cells 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 69 | Sphingolipid signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: ADORA1 |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 70 | Steroid hormone biosynthesis 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: CYP19A1 |
D00960 |
Anastrozole |
3件: 78, 86, 193 |
| 71 | Synaptic vesicle cycle 2 genes, 2 drugs (DrugBank) and 8 diseases shown |
2件: SLC6A2, SLC6A4 |
D00809 |
Amitriptyline |
3件: 78, 226, 299 |
| D07448 |
| 1件: SLC6A4 |
D00326 |
Fluoxetine |
6件: 13, 17, 78, 86, 179, 206 |
| D00823 |
| 72 | Systemic lupus erythematosus 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
| D03742 |
| D03744 |
| 73 | Taste transduction 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PDE1B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |
| 74 | Thermogenesis 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 75 | Thyroid cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 76 | Thyroid hormone signaling pathway 2 genes, 2 drugs (DrugBank) and 4 diseases shown |
2件: THRA, THRB |
D01010 |
Levothyroxine |
2件: 49, 78 |
| D08125 |
| D01011 |
Liothyronine |
3件: 13, 78, 212 |
| D08128 |
| 77 | Transcriptional misregulation in cancer 2 genes, 2 drugs (DrugBank) and 18 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
| D04870 |
| 1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
| D08378 |
| 78 | Vascular smooth muscle contraction 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
| D01453 |