| No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
| 1 | Adipocytokine signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 2 | AMPK signaling pathway 1 gene, 6 drugs (DrugBank) and 36 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
| D07474 |
| D00892 |
Fluvastatin |
3件: 79, 218, 222 |
| D07983 |
| D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
| D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
| D08410 |
| D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
| D08492 |
| D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
| 3 | Bile secretion 1 gene, 6 drugs (DrugBank) and 36 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
| D07474 |
| D00892 |
Fluvastatin |
3件: 79, 218, 222 |
| D07983 |
| D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
| D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
| D08410 |
| D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
| D08492 |
| D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
| 4 | cAMP signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 5 | Cholesterol metabolism 1 gene, 2 drugs (DrugBank) and 2 diseases shown |
1件: PCSK9 |
D10335 |
Alirocumab |
1件: 79 |
| D10557 |
Evolocumab |
2件: 79, 222 |
| 6 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: SERPINC1 |
D07510 |
Heparin |
11件: 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 |
| 7 | Fat digestion and absorption 2 genes, 2 drugs (DrugBank) and 4 diseases shown |
1件: MTTP |
D09637 |
Lomitapide |
1件: 79 |
| 1件: NPC1L1 |
D01966 |
Ezetimibe |
4件: 49, 79, 93, 260 |
| 8 | Glucagon signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 9 | Hepatitis C 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 10 | Insulin resistance 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 11 | Metabolic pathways 1 gene, 6 drugs (DrugBank) and 36 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
| D07474 |
| D00892 |
Fluvastatin |
3件: 79, 218, 222 |
| D07983 |
| D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
| D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
| D08410 |
| D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
| D08492 |
| D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
| 12 | Non-alcoholic fatty liver disease (NAFLD) 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 13 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
| 14 | Terpenoid backbone biosynthesis 1 gene, 6 drugs (DrugBank) and 36 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
| D07474 |
| D00892 |
Fluvastatin |
3件: 79, 218, 222 |
| D07983 |
| D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
| D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
| D08410 |
| D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
| D08492 |
| D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |