Home    Back

 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

A    B    C    D    E    F    G    H     I     J    K    L    M    N    O    P    Q    R    S    T    U    V    W    X    Y    Z    other

96 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Acute myeloid leukemia 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] RARA   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 2  Adipocytokine signaling pathway 
 2 genes, 2 drugs (DrugBank), 19 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 3  African trypanosomiasis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 4  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 5  Allograft rejection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 6  Alzheimer disease 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 7  Amoebiasis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 8  Amphetamine addiction 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 9  AMPK signaling pathway 
 1 gene, 2 drugs (DrugBank), 24 diseases shown 		  [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 10  Amyotrophic lateral sclerosis (ALS) 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 11  Antifolate resistance 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 12  Antigen processing and presentation 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 13  Apoptosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 14  Arachidonic acid metabolism 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] ALOX5   D00414   Zileuton   [3] 85, 160, 164 
 15  Asthma 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 16  Axon guidance 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 17  B cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 18  Bile secretion 
 1 gene, 2 drugs (DrugBank), 24 diseases shown 		  [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 19  C-type lectin receptor signaling pathway 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 20  Calcium signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 21  cAMP signaling pathway 
 1 gene, 1 drug (DrugBank), 5 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 22  Cellular senescence 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 23  cGMP-PKG signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 24  Chagas disease (American trypanosomiasis) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 25  Cytokine-cytokine receptor interaction 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] IL17A   D09967   Secukinumab   [7] 13, 37, 41, 46, 160, 269, 271 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 26  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 27  Dopaminergic synapse 
 3 genes, 1 drug (DrugBank), 1 disease shown 		  [3] PPP3CA, PPP3CB, PPP3CC   D05480   Pimecrolimus   [1] 160 
 28  Epstein-Barr virus infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 29  Estrogen signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] RARA   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 30  Fc epsilon RI signaling pathway 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] ALOX5   D00414   Zileuton   [3] 85, 160, 164 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 31  Fluid shear stress and atherosclerosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 32  Gastric cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] RARB   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 33  Glucagon signaling pathway 
 6 genes, 2 drugs (DrugBank), 5 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 34  Glutamatergic synapse 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 35  Graft-versus-host disease 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 36  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 37  Hepatitis B 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 38  Hepatitis C 
 2 genes, 2 drugs (DrugBank), 19 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 39  Herpes simplex virus 1 infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 40  Human cytomegalovirus infection 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 41  Human immunodeficiency virus 1 infection 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 42  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 43  Human T-cell leukemia virus 1 infection 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 44  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 45  IL-17 signaling pathway 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] IL17A   D09967   Secukinumab   [7] 13, 37, 41, 46, 160, 269, 271 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 46  Inflammatory bowel disease (IBD) 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] IL17A   D09967   Secukinumab   [7] 13, 37, 41, 46, 160, 269, 271 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 47  Influenza A 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 48  Insulin resistance 
 2 genes, 2 drugs (DrugBank), 19 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 49  Kaposi sarcoma-associated herpesvirus infection 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 50  Legionellosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 51  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 52  Long-term potentiation 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 53  Malaria 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 54  MAPK signaling pathway 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 55  Metabolic pathways 
 2 genes, 3 drugs (DrugBank), 26 diseases shown 		  [1] ALOX5   D00414   Zileuton   [3] 85, 160, 164 
 [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 56  mTOR signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 57  Natural killer cell mediated cytotoxicity 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 58  Necroptosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 59  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 60  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 61  Non-alcoholic fatty liver disease (NAFLD) 
 2 genes, 2 drugs (DrugBank), 19 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 62  Non-small cell lung cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] RARB   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 63  Oocyte meiosis 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 64  Osteoclast differentiation 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 65  Ovarian steroidogenesis 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] ALOX5   D00414   Zileuton   [3] 85, 160, 164 
 66  Oxytocin signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 67  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 68  Pathways in cancer 
 2 genes, 1 drug (DrugBank), 4 diseases shown 		  [2] RARA, RARB   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 69  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 70  Pertussis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 71  PPAR signaling pathway 
 1 gene, 1 drug (DrugBank), 5 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 72  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 73  Renin secretion 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 74  Rheumatoid arthritis 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] IL17A   D09967   Secukinumab   [7] 13, 37, 41, 46, 160, 269, 271 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 75  RIG-I-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 76  Serotonergic synapse 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] ALOX5   D00414   Zileuton   [3] 85, 160, 164 
 77  Shigellosis 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 78  Small cell lung cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] RARB   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 79  Sphingolipid signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 80  Systemic lupus erythematosus 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 81  T cell receptor signaling pathway 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 82  Terpenoid backbone biosynthesis 
 1 gene, 2 drugs (DrugBank), 24 diseases shown 		  [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 83  TGF-beta signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 84  Th1 and Th2 cell differentiation 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 85  Th17 cell differentiation 
 7 genes, 3 drugs (DrugBank), 10 diseases shown 		  [1] IL17A   D09967   Secukinumab   [7] 13, 37, 41, 46, 160, 269, 271 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] RARA   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 86  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 87  Toll-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 88  Toxoplasmosis 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] ALOX5   D00414   Zileuton   [3] 85, 160, 164 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 89  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] RARA   D00348   Isotretinoin   [4] 36, 39, 159, 160 
 90  Tuberculosis 
 6 genes, 2 drugs (DrugBank), 15 diseases shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 91  Type I diabetes mellitus 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 92  Type II diabetes mellitus 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 93  VEGF signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 94  Viral protein interaction with cytokine and cytokine receptor 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 
 95  Wnt signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D05480   Pimecrolimus   [1] 160 
 96  Yersinia infection 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] TNF   D02597   Adalimumab   [15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 

Back to top