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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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19 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adipocytokine signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 2  AMPK signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 3  Apelin signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 4  Autophagy - animal 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 5  Circadian rhythm 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 6  Fluid shear stress and atherosclerosis 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 7  FoxO signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 8  Glucagon signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 9  Hypertrophic cardiomyopathy (HCM) 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 10  Insulin resistance 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 11  Insulin signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 12  Longevity regulating pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 13  Longevity regulating pathway - multiple species 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 14  mTOR signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 15  Non-alcoholic fatty liver disease (NAFLD) 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 16  Oxytocin signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 17  PI3K-Akt signaling pathway 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 18  Thermogenesis 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 
 19  Tight junction 
 2 genes, 1 drug (DrugBank), 17 diseases shown 		  [2] PRKAA1, PRKAA2   D00944   Metformin   [17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 
 D04966 

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