Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carbonitrile----1件: 231 💬
220-valent pneumococcal conjugate vaccine----1件: 231 💬
34-PBA----1件: 231 💬
4[ARO-AAT]----1件: 231 💬
5AAV8hAAT(AVL)----1件: 231 💬
6Abdominal ultrasound----2件: 19, 231 💬
7Acetaminophen1件: Acetaminophen1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
8ADS-001----1件: 231 💬
9Aerosolized human Alpha-1 Antitrypsin----1件: 231 💬
10AIR-001 MD dose level 1----1件: 231 💬
11AIR-001 MD dose level 2----1件: 231 💬
12AIR-001 MD dose level 3----1件: 231 💬
13AIR-001 MD dose level 4----1件: 231 💬
14AIR-001 MD dose level 5----1件: 231 💬
15AIR-001 MD dose level 6----1件: 231 💬
16AIR-001 SAD dose level 1----1件: 231 💬
17AIR-001 SAD dose level 2----1件: 231 💬
18AIR-001 SAD dose level 3----1件: 231 💬
19AIR-001 SAD dose level 4----1件: 231 💬
20Albumin (Human) 20%, United States Pharmacopeia (USP)----1件: 231 💬
21Albuterol1件: Albuterol2件: Albuterol sulfate ,
Albuterol 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
22Albuterol inhaler.1件: Albuterol2件: Albuterol sulfate ,
Albuterol 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 231, 299 💬
23ALN-61444----1件: 231 💬
24ALN-77412----1件: 231 💬
25ALN-AAT----1件: 231 💬
26ALN-AAT02----1件: 231 💬
27Alpha 1-Antitrypsin----2件: 231, 298 💬
28Alpha 1-proteinase inhibitor (human)----1件: 231 💬
29Alpha-1 15%----1件: 231 💬
30Alpha-1 Antitrypsin (AAT)----1件: 231 💬
31Alpha-1 Antitrypsin (human)----1件: 231 💬
32Alpha-1 MP----1件: 231 💬
33Alpha-1 proteinase inhibitor (human)----1件: 231 💬
34ALPHA-1-ANTITRYPSIN----1件: 231 💬
35Alpha1-Proteinase Inhibitor----1件: 231 💬
36Alpha1-Proteinase Inhibitor (Human)----2件: 231, 299 💬
37ALVELESTAT1件: Alvelestat---1件: 231 💬
38Alvelestat (MPH966)1件: Alvelestat---1件: 231 💬
39Alvelestat oral tablet - dose 11件: Alvelestat---1件: 231 💬
40Alvelestat oral tablet - dose 21件: Alvelestat---1件: 231 💬
41Alvelestat tosylate1件: Alvelestat---1件: 231 💬
42API-AAT----1件: 231 💬
43API-AAT, AD00370, ARC-AAT, API drug Substance----1件: 231 💬
44ARC-AAT----1件: 231 💬
45ARC-AAT Injection----1件: 231 💬
46ARO-AAT1件: Fazirsiran---1件: 231 💬
47ARO-AAT Injection----1件: 231 💬
48Aspirin1件: Acetylsalicylic acid1件: Aspirin 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 22, 34, 48, 49, 51, 63, 86, 158, 210, 231 💬
49BEAM-302----1件: 231 💬
50Belcesiran1件: Belcesiran---1件: 231 💬
51Biological NTLA-3001----1件: 231 💬
52Blood draw----16件: 3, 6, 13, 19, 46, 48, 49, 51, 58, 65, 67, 193, 215, 231, 298, 299 💬
53Blood draw.----2件: 231, 299 💬
54BMN 349----1件: 231 💬
55Carbamazepine1件: Carbamazepine1件: Carbamazepine 💬 6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬6件: 6, 13, 137, 145, 158, 231 💬
56Diagnostic Test: Blood sampling----8件: 49, 51, 65, 74, 97, 127, 231, 299 💬
57Dose of 60 mg/kg alpha1-proteinase inhibitor----1件: 231 💬
58Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor----1件: 231 💬
59Drug-Carbamazepine (Tegretol XR)1件: Carbamazepine1件: Carbamazepine 💬 6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬1件: 231 💬
60Fazirsiran1件: Fazirsiran---1件: 231 💬
61Fazirsiran (TAK-999, also referred to as ARO-AAT) Injection1件: Fazirsiran---1件: 231 💬
62Fazirsiran (TAK-999, ARO-AAT) Injection1件: Fazirsiran---1件: 231 💬
63Fazisiran Injection----1件: 231 💬
64Fentanyl1件: Fentanyl3件: Fentanyl ,
Fentanyl citrate ,
Fentanyl hydrochloride 💬 		1件: OPRM1 💬 5件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬6件: 46, 70, 97, 215, 231, 298 💬
65Genetic: ADVM-043----1件: 231 💬
66Genetic: genetic sequencing----2件: 40, 231 💬
67Genetic: rAAV2-CB-hAAT Gene Vector----1件: 231 💬
68Glassia----1件: 231 💬
69History and physical----1件: 231 💬
70History and physical exam.----2件: 231, 299 💬
71Hyaluronic acid1件: Hyaluronic acid2件: Hyaluronate sodium ,
Hyaluronic acid 💬 		--5件: 46, 53, 70, 226, 231 💬
72Hyaluronic Acid Inhalation Solution1件: Hyaluronic acid2件: Hyaluronate sodium ,
Hyaluronic acid 💬 		--1件: 231 💬
73INBRX-1011件: INBRX-101---1件: 231 💬
74INBRX-101/rhAAT-Fc1件: INBRX-101---1件: 231 💬
75Intravenous catheter----1件: 231 💬
76Kamada -AAT for Inhalation or inhaled AAT (AAT)----1件: 231 💬
77Kamada -AAT for Inhalation or inhaled AAT (AAT)Pharmaceutical Form: Nebuliser solutionINN or Proposed INN: Alpha-1 Antitrypsin (AAT)CAS Number: 9041-92-3Current Sponsor code: Kamada-AATConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 20-Pharmaceutical form of the placebo: Nebuliser solutionRoute of administration of the placebo: Inhalation use----1件: 231 💬
78Kamada-AAT for inhalation----1件: 231 💬
79Kamada-AAT for Inhalation, 160mg----1件: 231 💬
80Kamada-AAT for Inhalation, 80mg----1件: 231 💬
81Kamada-API----1件: 231 💬
82KB408 (Nebulization)----1件: 231 💬
83KRRO-110----1件: 231 💬
84Lidocaine1件: Lidocaine3件: Lidocaine ,
Lidocaine hydrochloride ,
Lidocaine hydrochloride monohydrate 💬 		6件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		5件: Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬14件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
85Liver biopsy----3件: 171, 231, 240 💬
86Lorazepam1件: Lorazepam1件: Lorazepam 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		9件: Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 36, 231 💬
87Midazolam1件: Midazolam3件: Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		9件: Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬14件: 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
88MPH966----2件: 228, 231 💬
89None assigned----2件: 231, 299 💬
90OctaAlpha1----1件: 231 💬
91Ondansetron1件: Ondansetron2件: Ondansetron ,
Ondansetron hydrochloride hydrate 💬 		5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 97, 98, 107, 231 💬
92OsrhAAT 1 mg/kg IV----1件: 231 💬
93OsrhAAT 10 mg/kg IV----1件: 231 💬
94OsrhAAT 20 mg/kg IV----1件: 231 💬
95OsrhAAT 3 mg/kg IV----1件: 231 💬
96OsrhAAT 40 mg/kg IV----1件: 231 💬
97OsrhAAT 60 mg/kg IV----1件: 231 💬
98Other: Hyperpolarized 129Xe MRI----2件: 84, 231 💬
99Other: Liquid Alpha1-PI----1件: 231 💬
100Other: Liver questionnaire----1件: 231 💬
101Other: Sterile Normal Saline (0.9% NaCl)----1件: 231 💬
102Other: Withdrawal from alpha1 antitrypsin replacement therapy----1件: 231 💬
103Oxycodone1件: Oxycodone3件: Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬7件: 6, 13, 46, 70, 226, 231, 298 💬
104Oxycodone/Acetaminophen2件: Acetaminophen,
Oxycodone		4件: Acetaminophen ,
Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		5件: OPRD1,
OPRK1,
OPRM1,
PTGS1,
PTGS2 💬 		30件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Estrogen signaling pathway, Hormone signaling, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Sphingolipid signaling pathway, TNF signaling pathway, VEGF signaling pathway, cGMP-PKG signaling pathway 💬1件: 231 💬
105PHP-303----1件: 231 💬
106Prolastin----1件: 231 💬
107Prolastin-C----2件: 231, 298 💬
108Prolastin-C, 120 mg/kg----1件: 231 💬
109Prolastin-C, 60 mg/kg----1件: 231 💬
110Pulmonary function testing.----2件: 231, 299 💬
111RAAV1-CB-hAAT1件: rAAV1-CB-hAAT---1件: 231 💬
112RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR EXPRESSING THE HUMAN ALPHA-1-ANTITRYPSIN GENE----1件: 231 💬
113Retinoic Acid Receptor gamma Agonist----1件: 231 💬
114RO3300074----1件: 231 💬
115SAR447537----1件: 231 💬
116TAK-999, ARO-AAT1件: Fazirsiran---1件: 231 💬
117TSRA-196----1件: 231 💬
118VX-634----1件: 231 💬
119VX-668----1件: 231 💬
120VX-814----1件: 231 💬
121VX-864----1件: 231 💬
122VX864----1件: 231 💬
123WVE-006----1件: 231 💬
124YOLT-202----1件: 231 💬
125Zemaira----1件: 231 💬