Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1[A4250]----3件: 296, 297, 338 💬
2[Maralixibat]1件: Maralixibat2件: Maralixibat ,
Maralixibat chloride 💬 		2件: SLC10A1,
SLC10A2 💬 		3件: Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬2件: 296, 338 💬
3[OCA]----1件: 296 💬
4A4250----4件: 93, 296, 297, 338 💬
5Acetic acid1件: Acetic acid1件: Acetic acid, glacial 💬 --3件: 21, 97, 296 💬
6Acetylcysteine1件: Acetylcysteine1件: Acetylcysteine 💬 --25件: 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
7ACIDO OBETICOLICO----3件: 93, 94, 296 💬
8Ammonia1件: Ammonia1件: Ammonia solution, strong 💬 --6件: 6, 17, 86, 88, 251, 296 💬
9Basic treatment: sulperazone + ursodeoxycholic acid + compound glycyrrhizin + methylprednisolone + vitamin AD , D , E , K + imipenem or meropenem4件: Imipenem,
Meropenem,
Methylprednisolone,
Ursodeoxycholic acid		7件: Imipenem ,
Methylprednisolone ,
Ursodiol ,
Methylprednisolone acetate ,
Meropenem ,
Imipenem ,
Meropenem 💬 		2件: NR1H4,
NR3C1 💬 		2件: Bile secretion, Neuroactive ligand-receptor interaction 💬1件: 296 💬
10BELIMUMAB1件: Belimumab1件: Belimumab 💬 1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬17件: 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
11Bezafibrate1件: Bezafibrate1件: Bezafibrate 💬 1件: PPARA 💬 10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
12Bicarbonate Ringer's solution----1件: 296 💬
13Cefaclor1件: Cefaclor2件: Cefaclor ,
Cefaclor 💬 		--1件: 296 💬
14Cefoperazone1件: Cefoperazone2件: Cefoperazone sodium ,
Cefoperazone 💬 		--1件: 296 💬
15Corticosteroids----13件: 41, 46, 49, 63, 64, 97, 107, 113, 164, 222, 223, 296, 300 💬
16Cysteine1件: Cysteine2件: L-Cysteine ,
Cysteine hydrochloride 💬 		--13件: 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
17Desflurane1件: Desflurane1件: Desflurane 💬 --2件: 22, 296 💬
18Desflurane anesthetics1件: Desflurane1件: Desflurane 💬 --1件: 296 💬
19Dexamethasone1件: Dexamethasone3件: Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
20Diagnostic Test: Dry blood spot screening----1件: 296 💬
21DIMETHYL FUMARATE1件: Dimethyl fumarate1件: Dimethyl fumarate 💬 1件: KEAP1 💬 6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 20, 51, 86, 296 💬
22Filgrastim1件: Filgrastim1件: Filgrastim 💬 1件: CSF3R 💬 5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬30件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
23Folic acid1件: Folic acid2件: Folic acid ,
Folate sodium 💬 		--9件: 6, 46, 49, 50, 84, 97, 118, 172, 296 💬
24Gold1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
25Granulocyte Colony-Stimulating Factor----2件: 60, 296 💬
26High MCT formula----1件: 296 💬
27ICG Pulsion----1件: 296 💬
28ICG-Pulsion 25mg----1件: 296 💬
29IMIPENEM1件: Imipenem2件: Imipenem ,
Imipenem 💬 		--3件: 60, 296, 299 💬
30Indocyanine green2件: Indocyanine green,
Indocyanine green acid form		1件: Indocyanine green 💬 --9件: 22, 41, 46, 51, 96, 235, 278, 291, 296 💬
31Indocyanine Green (ICG)2件: Indocyanine green,
Indocyanine green acid form		1件: Indocyanine green 💬 --1件: 296 💬
32Intravenous immunoglobulin (IVIg)----8件: 14, 17, 19, 63, 65, 85, 164, 296 💬
33Kasai Portoenterostomy----1件: 296 💬
34Lactated Ringer----1件: 296 💬
35Lactobacillus casei1件: Lactobacillus casei1件: Lactobacillus casei 💬 --3件: 6, 97, 296 💬
36Lactobacillus casei rhamnosus (Lcr35)1件: Lactobacillus casei1件: Lactobacillus casei 💬 --1件: 296 💬
37Ligustrazine1件: Ligustrazine---2件: 46, 296 💬
38Lymph node and blood sampling----1件: 296 💬
39Magnesium1件: Magnesium---23件: 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
40Magnesium gluconate2件: Magnesium,
Magnesium gluconate		1件: Magnesium gluconate 💬 --2件: 296, 297 💬
41Magnesium sulfate2件: Magnesium,
Magnesium sulfate		1件: Magnesium sulfate 💬 --4件: 11, 97, 296, 297 💬
42Maralixibat1件: Maralixibat2件: Maralixibat ,
Maralixibat chloride 💬 		2件: SLC10A1,
SLC10A2 💬 		3件: Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬4件: 296, 297, 299, 338 💬
43Maralixibat (formely SHP625 or LUM001)1件: Maralixibat2件: Maralixibat ,
Maralixibat chloride 💬 		2件: SLC10A1,
SLC10A2 💬 		3件: Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬3件: 296, 297, 338 💬
44Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 5-Product Name: Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 10-Product Name: Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 15-Product Name: Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 20-1件: Maralixibat2件: Maralixibat ,
Maralixibat chloride 💬 		2件: SLC10A1,
SLC10A2 💬 		3件: Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬3件: 296, 297, 338 💬
45MARALIXIBAT CHLORIDE1件: Maralixibat2件: Maralixibat ,
Maralixibat chloride 💬 		2件: SLC10A1,
SLC10A2 💬 		3件: Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬3件: 296, 297, 338 💬
46Maralixibat cloruro1件: Maralixibat2件: Maralixibat ,
Maralixibat chloride 💬 		2件: SLC10A1,
SLC10A2 💬 		3件: Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬2件: 296, 338 💬
47Meloxicam1件: Meloxicam1件: Meloxicam 💬 1件: PTGS2 💬 22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 46, 49, 271, 296 💬
48MEROPENEM1件: Meropenem2件: Meropenem ,
Meropenem 💬 		--3件: 60, 296, 299 💬
49Methylprednisolone1件: Methylprednisolone2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
50N-acetyl Cysteine1件: Cysteine2件: L-Cysteine ,
Cysteine hydrochloride 💬 		--6件: 13, 34, 85, 88, 296, 310 💬
51N-Acetylcysteine1件: Acetylcysteine1件: Acetylcysteine 💬 --14件: 6, 13, 19, 20, 21, 49, 58, 85, 90, 111, 164, 296, 299, 337 💬
52Neomycin1件: Neomycin3件: Neomycin sulfate ,
Neomycin palmitate ,
Neomycin 💬 		--3件: 96, 97, 296 💬
53Norepinephrine1件: Norepinephrine3件: Noradrenaline ,
Norepinephrine bitartrate ,
Norepinephrine hydrochoride 💬 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 22, 296 💬
54Norepinephrine Bitartrate1件: Norepinephrine3件: Noradrenaline ,
Norepinephrine bitartrate ,
Norepinephrine hydrochoride 💬 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 296 💬
55Normal oral intake of the traditional formula----1件: 296 💬
56Normal Saline----20件: 6, 13, 17, 22, 36, 46, 49, 60, 70, 71, 79, 94, 96, 97, 210, 211, 226, 276, 296, 299 💬
57Obeticholic Acid1件: Obeticholic acid1件: Obeticholic acid 💬 1件: NR1H4 💬 1件: Bile secretion 💬3件: 93, 265, 296 💬
58OCA----3件: 93, 94, 296 💬
59OCA 0.1 mg----1件: 296 💬
60OCA 0.1mg----1件: 296 💬
61OCA 1.5mg----1件: 296 💬
62OCA 5mg----1件: 296 💬
63Ocaliva----2件: 93, 296 💬
64Odevixibat1件: Odevixibat2件: Odevixibat ,
Odevixibat hydrate 💬 		1件: SLC10A2 💬 1件: Bile secretion 💬3件: 296, 297, 338 💬
65Oral Vancomycin1件: Vancomycin2件: Vancomycin ,
Vancomycin hydrochloride 💬 		--3件: 94, 97, 296 💬
66Other Crystalloid----1件: 296 💬
67Other: Blood sampling----14件: 6, 13, 19, 46, 49, 51, 53, 58, 67, 127, 222, 266, 296, 299 💬
68Other: Control----12件: 6, 19, 67, 70, 75, 85, 96, 97, 162, 193, 226, 296 💬
69Other: explanted liver of BA patients sampling----1件: 296 💬
70Other: skin biopsy sampling----1件: 296 💬
71Pentoxifylline1件: Pentoxifylline1件: Pentoxifylline 💬 --13件: 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
72PREDNISOLONE1件: Prednisolone1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
73Propanolol----1件: 296 💬
74Prophylactic oral antibiotics: compound sulfamethoxazole tablet (SMZ/TMP) + cefaclor2件: Cefaclor,
Sulfamethoxazole		3件: Cefaclor ,
Sulfamethoxazole ,
Cefaclor 💬 		--1件: 296 💬
75Propofol1件: Propofol1件: Propofol 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		9件: Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
76Rifaximin1件: Rifaximin1件: Rifaximin 💬 --8件: 6, 65, 93, 96, 97, 99, 296, 299 💬
77RITUXIMAB1件: Rituximab1件: Rituximab 💬 1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
78Rocuronium1件: Rocuronium1件: Rocuronium bromide 💬 16件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB2,
CHRNB3,
CHRNB4 💬 		16件: Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 70, 296 💬
79Sevoflurane1件: Sevoflurane1件: Sevoflurane 💬 --8件: 6, 21, 22, 34, 70, 98, 225, 296 💬
80Sevoflurane anesthetics1件: Sevoflurane1件: Sevoflurane 💬 --1件: 296 💬
81Stem Cell----3件: 2, 113, 296 💬
82Sulfamethoxazole1件: Sulfamethoxazole1件: Sulfamethoxazole 💬 --8件: 35, 44, 49, 61, 85, 223, 296, 299 💬
83Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation----2件: 93, 296 💬
84Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs)----2件: 46, 296 💬
85Ursodeoxycholic acid1件: Ursodeoxycholic acid1件: Ursodiol 💬 1件: NR1H4 💬 1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
86Vancomycin1件: Vancomycin2件: Vancomycin ,
Vancomycin hydrochloride 💬 		--9件: 6, 13, 46, 70, 94, 96, 97, 296, 299 💬
87VO4CX----1件: 296 💬