Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1150-MG ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
2150MG ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
375-MG ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
4CF patients with A G551D mutation and treated with ivacaftor----1件: 299 💬
5Deuterated ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
6Elexacaftor / ivacaftor / tezacaftor1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
7Elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG, 2 tablets each morning + ivacaftor 150 MG ONE tablet each evening1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
8Elexacaftor-tezacaftor-ivacaftor exposure1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
9Elexacaftor-tezacaftor-ivacaftor treatment1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
10Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor (Ivacaftor),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
11Ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬2件: 299, 340 💬
12Ivacaftor 125MG tablet1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
13Ivacaftor 150 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
14Ivacaftor 150 MG or 250 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
15Ivacaftor 25 MG/75 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
16Ivacaftor 59,5MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
17Ivacaftor 59.5MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
18Ivacaftor 75 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
19Ivacaftor 75 MG/150 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
20Ivacaftor 75MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
21Ivacaftor and symdeko1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
22Ivacaftor exposed1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
23Ivacaftor or elexacaftor/tezacaftor/ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
24Ivacaftor+lumacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
25Ivacaftor/ataluren1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
26Ivacaftor/kalydeco1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
27Lumacaftor / ivacaftor2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
28Lumacaftor plus ivacaftor1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
29Lumacaftor plus ivacaftor combination2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
30Lumacaftor, ivacaftor drug combination1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
31Lumacaftor-ivacaftor1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
32Lumacaftor-ivacaftor treatment1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
33Lumacaftor/ivacaftor2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
34Lumacaftor/ivacaftor 100MG/125MG tablets2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
35Lumacaftor/ivacaftor 200MG/125MG2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
36Lumacaftor/ivacaftor 200MG/125MG tablets2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
37Lumacaftor/ivacaftor 200MG/83MG tablet2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
38Orkambi: contains lumacaftor and ivacaftor2件: Ivacaftor (Ivacaftor),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
39Tezacaftor/ivacaftor2件: Ivacaftor (Ivacaftor),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
40Tezacaftor/ivacaftor + ivacaftor1件: Tezacaftor1件: Tezacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
41Tezacaftor/ivacaftor 100MG/150MG2件: Ivacaftor (Ivacaftor),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
42Tezacaftor/ivacaftor/100MG/150MG2件: Ivacaftor (Ivacaftor),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
43Treatment with cystic fibrosis transmembrane regulator (cftr) modualtors ivacaftor, lumacaftor-ivacaftor, tezacaftor-ivacaftor, elexacaftor-tezacaftor-ivacaftor----1件: 299 💬
44VX-659/tezacaftor/ivacaftor2件: Ivacaftor (Ivacaftor),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
45VX-661 plus ivacaftor combination1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
46VX-661/ivacaftor1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
47VX-661/ivacaftor (VX-770) 100MG/150 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
48VX-661/ivacaftor 100 MG/ 150 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
49VX-661/ivacaftor 100MG/150 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
50VX-661/ivacaftor 100MG/150MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
51VX-661/ivacaftor 50 MG/ 75 MG1件: Ivacaftor (Ivacaftor)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬