Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1150-MG ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
2150MG ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
375-MG ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
4CF patients with A G551D mutation and treated with ivacaftor
(Kalydeco, KALYDECO)		----1件: 299 💬
5Deuterated ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
6Elexacaftor / ivacaftor / tezacaftor
(Kalydeco, KALYDECO)		1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
7Elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG, 2 tablets each morning + ivacaftor 150 MG ONE tablet each evening
(Kalydeco, KALYDECO)		1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
8Elexacaftor-tezacaftor-ivacaftor exposure
(Kalydeco, KALYDECO)		1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
9Elexacaftor-tezacaftor-ivacaftor treatment
(Kalydeco, KALYDECO)		1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
10Elexacaftor/tezacaftor/ivacaftor
(Kalydeco, KALYDECO)		3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: Ivacaftor (Kalydeco, KALYDECO),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
11Ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬2件: 299, 340 💬
12Ivacaftor 125MG tablet
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
13Ivacaftor 150 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
14Ivacaftor 150 MG or 250 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
15Ivacaftor 25 MG/75 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
16Ivacaftor 59,5MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
17Ivacaftor 59.5MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
18Ivacaftor 75 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
19Ivacaftor 75 MG/150 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
20Ivacaftor 75MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
21Ivacaftor and symdeko
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
22Ivacaftor exposed
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
23Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
24Ivacaftor+lumacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
25Ivacaftor/ataluren
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
26Ivacaftor/kalydeco1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
27Kalydeco1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬2件: 299, 340 💬
28Kalydeco 150 MG FILM-C1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
29Kalydeco 150 MG FILM-coated tablets1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
30Kalydeco 150MG1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
31Lumacaftor / ivacaftor
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
32Lumacaftor plus ivacaftor
(Kalydeco, KALYDECO)		1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
33Lumacaftor plus ivacaftor combination
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
34Lumacaftor, ivacaftor drug combination
(Kalydeco, KALYDECO)		1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
35Lumacaftor-ivacaftor
(Kalydeco, KALYDECO)		1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
36Lumacaftor-ivacaftor treatment
(Kalydeco, KALYDECO)		1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
37Lumacaftor/ivacaftor
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
38Lumacaftor/ivacaftor 100MG/125MG tablets
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
39Lumacaftor/ivacaftor 200MG/125MG
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
40Lumacaftor/ivacaftor 200MG/125MG tablets
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
41Lumacaftor/ivacaftor 200MG/83MG tablet
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
42Orkambi: contains lumacaftor and ivacaftor
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Lumacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
43Tezacaftor/ivacaftor
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
44Tezacaftor/ivacaftor + ivacaftor
(Kalydeco, KALYDECO)		1件: Tezacaftor1件: Tezacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
45Tezacaftor/ivacaftor 100MG/150MG
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
46Tezacaftor/ivacaftor/100MG/150MG
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
47Treatment with cystic fibrosis transmembrane regulator (cftr) modualtors ivacaftor, lumacaftor-ivacaftor, tezacaftor-ivacaftor, elexacaftor-tezacaftor-ivacaftor
(Kalydeco, KALYDECO)		----1件: 299 💬
48VX-659/tezacaftor/ivacaftor
(Kalydeco, KALYDECO)		2件: Ivacaftor,
Tezacaftor		2件: Ivacaftor (Kalydeco, KALYDECO),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
49VX-661 plus ivacaftor combination
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
50VX-661/ivacaftor
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
51VX-661/ivacaftor (VX-770) 100MG/150 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
52VX-661/ivacaftor 100 MG/ 150 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
53VX-661/ivacaftor 100MG/150 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
54VX-661/ivacaftor 100MG/150MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
55VX-661/ivacaftor 50 MG/ 75 MG
(Kalydeco, KALYDECO)		1件: Ivacaftor1件: Ivacaftor (Kalydeco, KALYDECO) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬