Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Dopamine Agonists (pramipexole, ropirinole)2件: Dopamine,
Pramipexole (Pramipexole dihydrochloride monohydrate)		4件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Dopamine hydrochloride ,
Pramipexole (Pramipexole),
Dopamine 💬 		5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
2Marketed Pramipexole ER1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
3Mirapex (pramipexole)1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
4P2B001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),2件: Pramipexole (Pramipexole dihydrochloride monohydrate),
Rasagiline		5件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Rasagiline mesylate ,
Pramipexole (Pramipexole),
Rasagiline ,
Rasagiline tartrate 💬 		4件: DRD2,
DRD3,
DRD4,
MAOB 💬 		19件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬1件: 6 💬
5P2B001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),2件: Pramipexole (Pramipexole dihydrochloride monohydrate),
Rasagiline		5件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Rasagiline mesylate ,
Pramipexole (Pramipexole),
Rasagiline ,
Rasagiline tartrate 💬 		4件: DRD2,
DRD3,
DRD4,
MAOB 💬 		19件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬1件: 6 💬
6Pramipexol----1件: 6 💬
7Pramipexol Extended Release----1件: 6 💬
8Pramipexol Immediate Release----1件: 6 💬
9Pramipexole1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 2, 6, 20, 74 💬
10Pramipexole 0.125 mg tablets1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
11Pramipexole 0.5 mg tablets1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
12Pramipexole 0.6 mg1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
13PRAMIPEXOLE DIHYDROCHLORIDE1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
14Pramipexole dihydrochloride extended-release tablets1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
15PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
16Pramipexole dihydrochloride monohydrate extended release1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
17Pramipexole ER1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
18Pramipexole Extended Release1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
19Pramipexole extended release tablet1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
20Pramipexole hydrochloride sustained-release tablet (Siforl®) Specification: 0.26mg/ tablet (in pramipexole)1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
21Pramipexole Immediate Release1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
22Pramipexole immediate release tablet1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
23Pramipexole IR1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
24Pramipexole or ropinirole2件: Pramipexole (Pramipexole dihydrochloride monohydrate),
Ropinirole		4件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Ropinirole hydrochloride ,
Pramipexole (Pramipexole),
Ropinirole 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
25Pramipexole SR1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
26Praxol hydrochloride sustained release tablet Specification: 0.375mg/ tablet (in pramipexole hydrochloride)1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
27R(+) pramipexole dihydrochloride monohydrate1件: Pramipexole (Pramipexole dihydrochloride monohydrate)2件: Pramipexole dihydrochloride (Pramipexole dihydrochloride, Pramipexole hydrochloride hydrate, Pramipexole dihydrochloride monohydrate),
Pramipexole (Pramipexole) 💬 		3件: DRD2,
DRD3,
DRD4 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 2 💬