Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Ambrisentan plus Spironolactone
(D00443)		2件: Ambrisentan,
Spironolactone		2件: Spironolactone (D00443),
Ambrisentan 💬 		2件: EDNRA,
NR3C2 💬 		8件: Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
2Ramipril Tritace®, Carvedilol Carvid®,and Spironolactone Aldactone®
(D00443)		3件: Carvedilol,
Ramipril,
Spironolactone		4件: Carvedilol ,
Ramipril ,
Spironolactone (D00443),
Carvedilol phosphate 💬 		7件: ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬 		21件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Hypertrophic cardiomyopathy, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 57 💬
3Spironolactone
(D00443)		1件: Spironolactone1件: Spironolactone (D00443) 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬12件: 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
4Spironolactone (drug)
(D00443)		1件: Spironolactone1件: Spironolactone (D00443) 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬1件: 210 💬
5Spironolactone and conivaptan
(D00443)		2件: Conivaptan,
Spironolactone		3件: Spironolactone (D00443),
Conivaptan hydrochloride ,
Conivaptan 💬 		3件: AVPR1A,
AVPR2,
NR3C2 💬 		7件: Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 86 💬
6Spironolactone captopril carvedilol
(D00443)		3件: Captopril,
Carvedilol,
Spironolactone		4件: Captopril ,
Carvedilol ,
Spironolactone (D00443),
Carvedilol phosphate 💬 		7件: ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬 		21件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Hypertrophic cardiomyopathy, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
7Spironolactone Mylan 25 mg comprimé pelliculé sécable
(D00443)		1件: Spironolactone1件: Spironolactone (D00443) 💬 1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬1件: 46 💬
8Spironolactone or Finerenone
(D00443)		2件: Finerenone,
Spironolactone		2件: Spironolactone (D00443),
Finerenone 💬 		1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬1件: 218 💬
9Treatment with Dapagliflozin followed by Spironolactone followed by their combination
(D00443)		2件: Dapagliflozin,
Spironolactone		2件: Spironolactone (D00443),
Dapagliflozin 💬 		1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬1件: 218 💬
10Treatment with Spironolactone followed by Dapagliflozin followed by their combination
(D00443)		2件: Dapagliflozin,
Spironolactone		2件: Spironolactone (D00443),
Dapagliflozin 💬 		1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬1件: 218 💬