Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Mexiletine hydrochloride 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
2 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Mexiletine 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
3 Breast cancer 💬
 1件: PGR 💬 Ulipristal 💬 Ulipristal 1件: 10 💬
4 Breast cancer 💬
 1件: PGR 💬 Ulipristal acetate 💬 Ulipristal 1件: 10 💬
5 Cadherin signaling 💬
 1件: SCN5A 💬 Mexiletine hydrochloride 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
6 Cadherin signaling 💬
 1件: SCN5A 💬 Mexiletine 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
7 cAMP signaling pathway 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
8 cGMP-PKG signaling pathway 💬
 1件: OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
9 cGMP-PKG signaling pathway 💬
 1件: OPRD1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
10 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Ulipristal 💬 Ulipristal 1件: 10 💬
11 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Ulipristal acetate 💬 Ulipristal 1件: 10 💬
12 Dopaminergic synapse 💬
 1件: SCN1A 💬 Mexiletine hydrochloride 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
13 Dopaminergic synapse 💬
 1件: SCN1A 💬 Mexiletine 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
14 Estrogen signaling pathway 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
15 Estrogen signaling pathway 💬
 1件: OPRM1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
16 Estrogen signaling pathway 💬
 1件: OPRM1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
17 Estrogen signaling pathway 💬
 1件: PGR 💬 Ulipristal 💬 Ulipristal 1件: 10 💬
18 Estrogen signaling pathway 💬
 1件: PGR 💬 Ulipristal acetate 💬 Ulipristal 1件: 10 💬
19 Folate biosynthesis 💬
 1件: AKR1B1 💬 Epalrestat 💬 Epalrestat 1件: 10 💬
20 Fructose and mannose metabolism 💬
 1件: AKR1B1 💬 Epalrestat 💬 Epalrestat 1件: 10 💬
21 GABAergic synapse 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
22 Galactose metabolism 💬
 1件: AKR1B1 💬 Epalrestat 💬 Epalrestat 1件: 10 💬
23 Glycerolipid metabolism 💬
 1件: AKR1B1 💬 Epalrestat 💬 Epalrestat 1件: 10 💬
24 GnRH secretion 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
25 Hormone signaling 💬
 3件: OPRD1, OPRK1, OPRM1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
26 Hormone signaling 💬
 3件: OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
27 IgSF CAM signaling 💬
 1件: SCN8A 💬 Mexiletine hydrochloride 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
28 IgSF CAM signaling 💬
 1件: SCN8A 💬 Mexiletine 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
29 Morphine addiction 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
30 Morphine addiction 💬
 1件: OPRM1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
31 Morphine addiction 💬
 1件: OPRM1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
32 Neuroactive ligand signaling 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
33 Neuroactive ligand signaling 💬
 3件: OPRD1, OPRK1, OPRM1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
34 Neuroactive ligand signaling 💬
 3件: OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
35 Neuroactive ligand-receptor interaction 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
36 Neuroactive ligand-receptor interaction 💬
 3件: OPRD1, OPRK1, OPRM1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
37 Neuroactive ligand-receptor interaction 💬
 3件: OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
38 Oocyte meiosis 💬
 1件: PGR 💬 Ulipristal 💬 Ulipristal 1件: 10 💬
39 Oocyte meiosis 💬
 1件: PGR 💬 Ulipristal acetate 💬 Ulipristal 1件: 10 💬
40 Pentose and glucuronate interconversions 💬
 1件: AKR1B1 💬 Epalrestat 💬 Epalrestat 1件: 10 💬
41 Progesterone-mediated oocyte maturation 💬
 1件: PGR 💬 Ulipristal 💬 Ulipristal 1件: 10 💬
42 Progesterone-mediated oocyte maturation 💬
 1件: PGR 💬 Ulipristal acetate 💬 Ulipristal 1件: 10 💬
43 Sphingolipid signaling pathway 💬
 1件: OPRD1 💬 Naltrexone hydrochloride 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
44 Sphingolipid signaling pathway 💬
 1件: OPRD1 💬 Naltrexone 💬 Naltrexone 14件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
45 Taste transduction 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
46 Taste transduction 💬
 3件: SCN2A, SCN3A, SCN9A 💬 Mexiletine hydrochloride 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬
47 Taste transduction 💬
 3件: SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine 6件:  1 ,  2 , 10, 113, 114, 115 💬

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