Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | ||||||||||||||||||||||||||||||||||||||||||||
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| 1 | African trypanosomiasis 💬 10 genes, 24 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬African trypanosomiasis
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Canakinumab Canakinumab 💬African trypanosomiasis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬1. African trypanosomiasis
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| 2 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 58 drugs (DrugBank) and 100 diseases |
IL1B 1件: IL1B 💬AGE-RAGE signaling pathway in diabetic complications
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Canakinumab Canakinumab 💬AGE-RAGE signaling pathway in diabetic complications
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬2. AGE-RAGE signaling pathway in diabetic complications
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| 3 | Alcoholic liver disease 💬 43 genes, 56 drugs (DrugBank) and 98 diseases |
IL1B 1件: IL1B 💬Alcoholic liver disease
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Canakinumab Canakinumab 💬Alcoholic liver disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬3. Alcoholic liver disease
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| 4 | Alzheimer disease 💬 59 genes, 136 drugs (DrugBank) and 139 diseases |
IL1B 1件: IL1B 💬Alzheimer disease
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Canakinumab Canakinumab 💬Alzheimer disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬4. Alzheimer disease
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| 5 | Amoebiasis 💬 20 genes, 32 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬Amoebiasis
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Canakinumab Canakinumab 💬Amoebiasis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬5. Amoebiasis
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| 6 | C-type lectin receptor signaling pathway 💬 28 genes, 71 drugs (DrugBank) and 108 diseases |
IL1B 1件: IL1B 💬C-type lectin receptor signaling pathway
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Canakinumab Canakinumab 💬C-type lectin receptor signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬6. C-type lectin receptor signaling pathway
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| 7 | Chagas disease 💬 32 genes, 59 drugs (DrugBank) and 88 diseases |
IL1B 1件: IL1B 💬Chagas disease
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Canakinumab Canakinumab 💬Chagas disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬7. Chagas disease
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| 8 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
IL1B 1件: IL1B 💬Coronavirus disease
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Canakinumab Canakinumab 💬Coronavirus disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬8. Coronavirus disease
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| 9 | Cytokine-cytokine receptor interaction 💬 90 genes, 141 drugs (DrugBank) and 104 diseases |
IL1B 1件: IL1B 💬Cytokine-cytokine receptor interaction
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Canakinumab Canakinumab 💬Cytokine-cytokine receptor interaction
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬9. Cytokine-cytokine receptor interaction
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| 10 | Cytosolic DNA-sensing pathway 💬 21 genes, 17 drugs (DrugBank) and 34 diseases |
IL1B 1件: IL1B 💬Cytosolic DNA-sensing pathway
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Canakinumab Canakinumab 💬Cytosolic DNA-sensing pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬10. Cytosolic DNA-sensing pathway
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| 11 | Fluid shear stress and atherosclerosis 💬 33 genes, 60 drugs (DrugBank) and 100 diseases |
IL1B 1件: IL1B 💬Fluid shear stress and atherosclerosis
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Canakinumab Canakinumab 💬Fluid shear stress and atherosclerosis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬11. Fluid shear stress and atherosclerosis
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| 12 | Graft-versus-host disease 💬 28 genes, 26 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬Graft-versus-host disease
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Canakinumab Canakinumab 💬Graft-versus-host disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬12. Graft-versus-host disease
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| 13 | Hematopoietic cell lineage 💬 47 genes, 97 drugs (DrugBank) and 101 diseases |
IL1B 1件: IL1B 💬Hematopoietic cell lineage
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Canakinumab Canakinumab 💬Hematopoietic cell lineage
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬13. Hematopoietic cell lineage
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| 14 | Herpes simplex virus 1 infection 💬 71 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B 1件: IL1B 💬Herpes simplex virus 1 infection
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Canakinumab Canakinumab 💬Herpes simplex virus 1 infection
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬14. Herpes simplex virus 1 infection
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| 15 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
IL1B 1件: IL1B 💬Human cytomegalovirus infection
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Canakinumab Canakinumab 💬Human cytomegalovirus infection
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬15. Human cytomegalovirus infection
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| 16 | IL-17 signaling pathway 💬 20 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬IL-17 signaling pathway
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Canakinumab Canakinumab 💬IL-17 signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬16. IL-17 signaling pathway
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| 17 | Inflammatory bowel disease 💬 38 genes, 49 drugs (DrugBank) and 75 diseases |
IL1B 1件: IL1B 💬Inflammatory bowel disease
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Canakinumab Canakinumab 💬Inflammatory bowel disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬17. Inflammatory bowel disease
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| 18 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
IL1B 1件: IL1B 💬Inflammatory mediator regulation of TRP channels
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Canakinumab Canakinumab 💬Inflammatory mediator regulation of TRP channels
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬18. Inflammatory mediator regulation of TRP channels
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| 19 | Influenza A 💬 67 genes, 84 drugs (DrugBank) and 101 diseases |
IL1B 1件: IL1B 💬Influenza A
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Canakinumab Canakinumab 💬Influenza A
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬19. Influenza A
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| 20 | Legionellosis 💬 10 genes, 24 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬Legionellosis
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Canakinumab Canakinumab 💬Legionellosis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬20. Legionellosis
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| 21 | Leishmaniasis 💬 40 genes, 76 drugs (DrugBank) and 105 diseases |
IL1B 1件: IL1B 💬Leishmaniasis
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Canakinumab Canakinumab 💬Leishmaniasis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬21. Leishmaniasis
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| 22 | Lipid and atherosclerosis 💬 52 genes, 73 drugs (DrugBank) and 107 diseases |
IL1B 1件: IL1B 💬Lipid and atherosclerosis
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Canakinumab Canakinumab 💬Lipid and atherosclerosis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬22. Lipid and atherosclerosis
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| 23 | Malaria 💬 17 genes, 31 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬Malaria
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Canakinumab Canakinumab 💬Malaria
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬23. Malaria
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| 24 | MAPK signaling pathway 💬 70 genes, 101 drugs (DrugBank) and 117 diseases |
IL1B 1件: IL1B 💬MAPK signaling pathway
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Canakinumab Canakinumab 💬MAPK signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬24. MAPK signaling pathway
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| 25 | Measles 💬 42 genes, 72 drugs (DrugBank) and 70 diseases |
IL1B 1件: IL1B 💬Measles
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Canakinumab Canakinumab 💬Measles
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬25. Measles
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| 26 | Necroptosis 💬 34 genes, 60 drugs (DrugBank) and 82 diseases |
IL1B 1件: IL1B 💬Necroptosis
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Canakinumab Canakinumab 💬Necroptosis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬26. Necroptosis
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| 27 | NF-kappa B signaling pathway 💬 23 genes, 81 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬NF-kappa B signaling pathway
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Canakinumab Canakinumab 💬NF-kappa B signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬27. NF-kappa B signaling pathway
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| 28 | NOD-like receptor signaling pathway 💬 33 genes, 57 drugs (DrugBank) and 79 diseases |
IL1B 1件: IL1B 💬NOD-like receptor signaling pathway
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Canakinumab Canakinumab 💬NOD-like receptor signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬28. NOD-like receptor signaling pathway
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| 29 | Non-alcoholic fatty liver disease 💬 24 genes, 54 drugs (DrugBank) and 100 diseases |
IL1B 1件: IL1B 💬Non-alcoholic fatty liver disease
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Canakinumab Canakinumab 💬Non-alcoholic fatty liver disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬29. Non-alcoholic fatty liver disease
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| 30 | Osteoclast differentiation 💬 40 genes, 93 drugs (DrugBank) and 109 diseases |
IL1B 1件: IL1B 💬Osteoclast differentiation
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Canakinumab Canakinumab 💬Osteoclast differentiation
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬30. Osteoclast differentiation
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| 31 | Pathogenic Escherichia coli infection 💬 31 genes, 46 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬Pathogenic Escherichia coli infection
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Canakinumab Canakinumab 💬Pathogenic Escherichia coli infection
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬31. Pathogenic Escherichia coli infection
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| 32 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
IL1B 1件: IL1B 💬Pathways of neurodegeneration - multiple diseases
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Canakinumab Canakinumab 💬Pathways of neurodegeneration - multiple diseases
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬32. Pathways of neurodegeneration - multiple diseases
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| 33 | Pertussis 💬 23 genes, 48 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬Pertussis
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Canakinumab Canakinumab 💬Pertussis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬33. Pertussis
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| 34 | Prion disease 💬 41 genes, 77 drugs (DrugBank) and 121 diseases |
IL1B 1件: IL1B 💬Prion disease
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Canakinumab Canakinumab 💬Prion disease
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬34. Prion disease
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| 35 | Rheumatoid arthritis 💬 39 genes, 59 drugs (DrugBank) and 85 diseases |
IL1B 1件: IL1B 💬Rheumatoid arthritis
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Canakinumab Canakinumab 💬Rheumatoid arthritis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬35. Rheumatoid arthritis
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| 36 | Salmonella infection 💬 32 genes, 48 drugs (DrugBank) and 78 diseases |
IL1B 1件: IL1B 💬Salmonella infection
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Canakinumab Canakinumab 💬Salmonella infection
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬36. Salmonella infection
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| 37 | Shigellosis 💬 31 genes, 54 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬Shigellosis
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Canakinumab Canakinumab 💬Shigellosis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬37. Shigellosis
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| 38 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
IL1B 1件: IL1B 💬Th17 cell differentiation
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Canakinumab Canakinumab 💬Th17 cell differentiation
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬38. Th17 cell differentiation
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| 39 | TNF signaling pathway 💬 25 genes, 64 drugs (DrugBank) and 95 diseases |
IL1B 1件: IL1B 💬TNF signaling pathway
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Canakinumab Canakinumab 💬TNF signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬39. TNF signaling pathway
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| 40 | Toll-like receptor signaling pathway 💬 41 genes, 68 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬Toll-like receptor signaling pathway
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Canakinumab Canakinumab 💬Toll-like receptor signaling pathway
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬40. Toll-like receptor signaling pathway
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| 41 | Tuberculosis 💬 67 genes, 80 drugs (DrugBank) and 104 diseases |
IL1B 1件: IL1B 💬Tuberculosis
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Canakinumab Canakinumab 💬Tuberculosis
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬41. Tuberculosis
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| 42 | Type I diabetes mellitus 💬 32 genes, 25 drugs (DrugBank) and 72 diseases |
IL1B 1件: IL1B 💬Type I diabetes mellitus
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Canakinumab Canakinumab 💬Type I diabetes mellitus
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬42. Type I diabetes mellitus
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| 43 | Yersinia infection 💬 25 genes, 43 drugs (DrugBank) and 78 diseases |
IL1B 1件: IL1B 💬Yersinia infection
|
Canakinumab Canakinumab 💬Yersinia infection
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬43. Yersinia infection
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African trypanosomiasis
10 genes, 24 drugs (DrugBank) and 66 diseases
AGE-RAGE signaling pathway in diabetic complications
28 genes, 58 drugs (DrugBank) and 100 diseases
Alcoholic liver disease
43 genes, 56 drugs (DrugBank) and 98 diseases
Alzheimer disease
59 genes, 136 drugs (DrugBank) and 139 diseases
Amoebiasis
20 genes, 32 drugs (DrugBank) and 77 diseases
C-type lectin receptor signaling pathway
28 genes, 71 drugs (DrugBank) and 108 diseases
Chagas disease
32 genes, 59 drugs (DrugBank) and 88 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Cytokine-cytokine receptor interaction
90 genes, 141 drugs (DrugBank) and 104 diseases
Cytosolic DNA-sensing pathway
21 genes, 17 drugs (DrugBank) and 34 diseases
Fluid shear stress and atherosclerosis
33 genes, 60 drugs (DrugBank) and 100 diseases
Graft-versus-host disease
28 genes, 26 drugs (DrugBank) and 68 diseases
Hematopoietic cell lineage
47 genes, 97 drugs (DrugBank) and 101 diseases
Herpes simplex virus 1 infection
71 genes, 85 drugs (DrugBank) and 110 diseases
Human cytomegalovirus infection
65 genes, 121 drugs (DrugBank) and 136 diseases
IL-17 signaling pathway
20 genes, 65 drugs (DrugBank) and 91 diseases
Inflammatory bowel disease
38 genes, 49 drugs (DrugBank) and 75 diseases
Inflammatory mediator regulation of TRP channels
26 genes, 55 drugs (DrugBank) and 70 diseases
Influenza A
67 genes, 84 drugs (DrugBank) and 101 diseases
Legionellosis
10 genes, 24 drugs (DrugBank) and 68 diseases
Leishmaniasis
40 genes, 76 drugs (DrugBank) and 105 diseases
Lipid and atherosclerosis
52 genes, 73 drugs (DrugBank) and 107 diseases
Malaria
17 genes, 31 drugs (DrugBank) and 69 diseases
MAPK signaling pathway
70 genes, 101 drugs (DrugBank) and 117 diseases
Measles
42 genes, 72 drugs (DrugBank) and 70 diseases
Necroptosis
34 genes, 60 drugs (DrugBank) and 82 diseases
NF-kappa B signaling pathway
23 genes, 81 drugs (DrugBank) and 97 diseases
NOD-like receptor signaling pathway
33 genes, 57 drugs (DrugBank) and 79 diseases
Non-alcoholic fatty liver disease
24 genes, 54 drugs (DrugBank) and 100 diseases
Osteoclast differentiation
40 genes, 93 drugs (DrugBank) and 109 diseases
Pathogenic Escherichia coli infection
31 genes, 46 drugs (DrugBank) and 84 diseases
Pathways of neurodegeneration - multiple diseases
64 genes, 143 drugs (DrugBank) and 141 diseases
Pertussis
23 genes, 48 drugs (DrugBank) and 77 diseases
Prion disease
41 genes, 77 drugs (DrugBank) and 121 diseases
Rheumatoid arthritis
39 genes, 59 drugs (DrugBank) and 85 diseases
Salmonella infection
32 genes, 48 drugs (DrugBank) and 78 diseases
Shigellosis
31 genes, 54 drugs (DrugBank) and 97 diseases
Th17 cell differentiation
57 genes, 88 drugs (DrugBank) and 111 diseases
TNF signaling pathway
25 genes, 64 drugs (DrugBank) and 95 diseases
Toll-like receptor signaling pathway
41 genes, 68 drugs (DrugBank) and 84 diseases
Tuberculosis
67 genes, 80 drugs (DrugBank) and 104 diseases
Type I diabetes mellitus
32 genes, 25 drugs (DrugBank) and 72 diseases
Yersinia infection
25 genes, 43 drugs (DrugBank) and 78 diseases