Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Amoebiasis 💬 20 genes, 32 drugs (DrugBank) and 77 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Amoebiasis
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬1. Amoebiasis
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| 2 | Amyotrophic lateral sclerosis 💬 39 genes, 58 drugs (DrugBank) and 116 diseases |
SIGMAR1 1件: SIGMAR1 💬Amyotrophic lateral sclerosis
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Amyotrophic lateral sclerosis
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬2. Amyotrophic lateral sclerosis |
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| 3 | Amyotrophic lateral sclerosis 💬 39 genes, 58 drugs (DrugBank) and 116 diseases |
SIGMAR1 1件: SIGMAR1 💬Amyotrophic lateral sclerosis
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Fenfluramine Fenfluramine 💬Amyotrophic lateral sclerosis
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬2. Amyotrophic lateral sclerosis |
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| 4 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
HTR2A 1件: HTR2A 💬Calcium signaling pathway
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Psilocybin Psilocybin 💬Calcium signaling pathway
| Psilocybin | 002 5件: 2 , 6 , 13, 149, 206 💬4. Calcium signaling pathway |
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| 5 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
HTR2A 2件: HTR2A, HTR2C 💬
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Calcium signaling pathway
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬5. Calcium signaling pathway |
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| 6 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
HTR2A 2件: HTR2A, HTR2C 💬
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Fenfluramine Fenfluramine 💬Calcium signaling pathway
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬5. Calcium signaling pathway |
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| 7 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬cAMP signaling pathway
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬7. cAMP signaling pathway
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| 8 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
HTR1D 1件: HTR1D 💬cAMP signaling pathway
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬cAMP signaling pathway
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬8. cAMP signaling pathway |
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| 9 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
HTR1D 1件: HTR1D 💬cAMP signaling pathway
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Fenfluramine Fenfluramine 💬cAMP signaling pathway
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬8. cAMP signaling pathway |
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| 10 | Circadian entrainment 💬 22 genes, 42 drugs (DrugBank) and 62 diseases |
MTNR1A 2件: MTNR1A, MTNR1B 💬
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Melatonin Melatonin 💬Circadian entrainment
| Melatonin | 002 18件: 2 , 6 , 8 , 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬10. Circadian entrainment
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| 11 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
IL6R 1件: IL6R 💬Coronavirus disease
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Tocilizumab Tocilizumab 💬Coronavirus disease
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬11. Coronavirus disease
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| 12 | Cytokine-cytokine receptor interaction 💬 90 genes, 141 drugs (DrugBank) and 104 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Cytokine-cytokine receptor interaction
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬12. Cytokine-cytokine receptor interaction
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| 13 | Cytokine-cytokine receptor interaction 💬 90 genes, 141 drugs (DrugBank) and 104 diseases |
IL6R 1件: IL6R 💬Cytokine-cytokine receptor interaction
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Tocilizumab Tocilizumab 💬Cytokine-cytokine receptor interaction
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬13. Cytokine-cytokine receptor interaction
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| 14 | ECM-receptor interaction 💬 9 genes, 11 drugs (DrugBank) and 16 diseases |
SV2A 1件: SV2A 💬ECM-receptor interaction
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Brivaracetam Brivaracetam 💬ECM-receptor interaction
| Brivaracetam | 149 2件: 149, 309 💬
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| 15 | ECM-receptor interaction 💬 9 genes, 11 drugs (DrugBank) and 16 diseases |
SV2A 1件: SV2A 💬ECM-receptor interaction
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Levetiracetam Levetiracetam 💬ECM-receptor interaction
| Levetiracetam | 002 7件: 2 , 4 , 6 , 13, 34, 149, 307 💬15. ECM-receptor interaction
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| 16 | ECM-receptor interaction 💬 9 genes, 11 drugs (DrugBank) and 16 diseases |
SV2A 3件: SV2A, SV2B, SV2C 💬
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Padsevonil Padsevonil 💬ECM-receptor interaction
| Padsevonil | 149 1件: 149 💬16. ECM-receptor interaction
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| 17 | Estrogen signaling pathway 💬 20 genes, 80 drugs (DrugBank) and 70 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬Estrogen signaling pathway
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬17. Estrogen signaling pathway
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| 18 | Fat digestion and absorption 💬 3 genes, 3 drugs (DrugBank) and 5 diseases |
NPC1L1 1件: NPC1L1 💬Fat digestion and absorption
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Ezetimibe Ezetimibe 💬Fat digestion and absorption
| Ezetimibe | 049 5件: 49, 79, 93, 149, 260 💬18. Fat digestion and absorption |
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| 19 | Fluid shear stress and atherosclerosis 💬 33 genes, 60 drugs (DrugBank) and 100 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Fluid shear stress and atherosclerosis
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬19. Fluid shear stress and atherosclerosis
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| 20 | GABAergic synapse 💬 29 genes, 42 drugs (DrugBank) and 57 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬GABAergic synapse
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬20. GABAergic synapse
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| 21 | Gap junction 💬 27 genes, 103 drugs (DrugBank) and 87 diseases |
HTR2A 1件: HTR2A 💬Gap junction
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Psilocybin Psilocybin 💬Gap junction
| Psilocybin | 002 5件: 2 , 6 , 13, 149, 206 💬
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| 22 | Gap junction 💬 27 genes, 103 drugs (DrugBank) and 87 diseases |
HTR2A 2件: HTR2A, HTR2C 💬
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Gap junction
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬
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| 23 | Gap junction 💬 27 genes, 103 drugs (DrugBank) and 87 diseases |
HTR2A 2件: HTR2A, HTR2C 💬
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Fenfluramine Fenfluramine 💬Gap junction
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬
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| 24 | GnRH secretion 💬 27 genes, 49 drugs (DrugBank) and 62 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬GnRH secretion
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬24. GnRH secretion
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| 25 | Hematopoietic cell lineage 💬 47 genes, 97 drugs (DrugBank) and 101 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Hematopoietic cell lineage
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬25. Hematopoietic cell lineage
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| 26 | Hematopoietic cell lineage 💬 47 genes, 97 drugs (DrugBank) and 101 diseases |
IL6R 1件: IL6R 💬Hematopoietic cell lineage
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Tocilizumab Tocilizumab 💬Hematopoietic cell lineage
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬26. Hematopoietic cell lineage
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| 27 | HIF-1 signaling pathway 💬 26 genes, 56 drugs (DrugBank) and 87 diseases |
IL6R 1件: IL6R 💬HIF-1 signaling pathway
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Tocilizumab Tocilizumab 💬HIF-1 signaling pathway
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬27. HIF-1 signaling pathway
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| 28 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
IL1R1 1件: IL1R1 💬Human cytomegalovirus infection
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Anakinra Anakinra 💬Human cytomegalovirus infection
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬28. Human cytomegalovirus infection
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| 29 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
IL6R 1件: IL6R 💬Human cytomegalovirus infection
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Tocilizumab Tocilizumab 💬Human cytomegalovirus infection
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬29. Human cytomegalovirus infection
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| 30 | Human T-cell leukemia virus 1 infection 💬 61 genes, 80 drugs (DrugBank) and 105 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Human T-cell leukemia virus 1 infection
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬30. Human T-cell leukemia virus 1 infection
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| 31 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
HTR2A 1件: HTR2A 💬Inflammatory mediator regulation of TRP channels
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Psilocybin Psilocybin 💬Inflammatory mediator regulation of TRP channels
| Psilocybin | 002 5件: 2 , 6 , 13, 149, 206 💬31. Inflammatory mediator regulation of TRP channels |
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| 32 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
HTR2A 2件: HTR2A, HTR2C 💬
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Inflammatory mediator regulation of TRP channels
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬32. Inflammatory mediator regulation of TRP channels |
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| 33 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
HTR2A 2件: HTR2A, HTR2C 💬
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Fenfluramine Fenfluramine 💬Inflammatory mediator regulation of TRP channels
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬32. Inflammatory mediator regulation of TRP channels |
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| 34 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
IL1R1 1件: IL1R1 💬Inflammatory mediator regulation of TRP channels
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Anakinra Anakinra 💬Inflammatory mediator regulation of TRP channels
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬34. Inflammatory mediator regulation of TRP channels
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| 35 | Insulin secretion 💬 16 genes, 51 drugs (DrugBank) and 61 diseases |
SNAP25 1件: SNAP25 💬Insulin secretion
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Botulinum toxin type A Botulinum toxin type A 💬Insulin secretion
| Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬35. Insulin secretion
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| 36 | Insulin secretion 💬 16 genes, 51 drugs (DrugBank) and 61 diseases |
SNAP25 1件: SNAP25 💬Insulin secretion
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Incobotulinumtoxin A Incobotulinumtoxin A 💬Insulin secretion
| Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬35. Insulin secretion
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| 37 | JAK-STAT signaling pathway 💬 60 genes, 117 drugs (DrugBank) and 116 diseases |
IL6R 1件: IL6R 💬JAK-STAT signaling pathway
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Tocilizumab Tocilizumab 💬JAK-STAT signaling pathway
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬37. JAK-STAT signaling pathway
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| 38 | MAPK signaling pathway 💬 70 genes, 101 drugs (DrugBank) and 117 diseases |
IL1R1 1件: IL1R1 💬MAPK signaling pathway
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Anakinra Anakinra 💬MAPK signaling pathway
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬38. MAPK signaling pathway
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| 39 | Morphine addiction 💬 43 genes, 70 drugs (DrugBank) and 80 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬Morphine addiction
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬39. Morphine addiction
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| 40 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬Neuroactive ligand signaling
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬40. Neuroactive ligand signaling
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| 41 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
HTR1D 4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Neuroactive ligand signaling
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬41. Neuroactive ligand signaling |
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| 42 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
HTR1D 4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬
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Fenfluramine Fenfluramine 💬Neuroactive ligand signaling
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬41. Neuroactive ligand signaling |
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| 43 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
HTR2A 1件: HTR2A 💬Neuroactive ligand signaling
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Psilocybin Psilocybin 💬Neuroactive ligand signaling
| Psilocybin | 002 5件: 2 , 6 , 13, 149, 206 💬43. Neuroactive ligand signaling |
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| 44 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
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Baclofen Baclofen 💬Neuroactive ligand-receptor interaction
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬44. Neuroactive ligand-receptor interaction
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| 45 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
HTR1D 3件: HTR1D, HTR2A, HTR2C 💬
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Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Neuroactive ligand-receptor interaction
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬45. Neuroactive ligand-receptor interaction |
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| 46 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
HTR1D 3件: HTR1D, HTR2A, HTR2C 💬
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Fenfluramine Fenfluramine 💬Neuroactive ligand-receptor interaction
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬45. Neuroactive ligand-receptor interaction |
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| 47 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
HTR2A 1件: HTR2A 💬Neuroactive ligand-receptor interaction
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Psilocybin Psilocybin 💬Neuroactive ligand-receptor interaction
| Psilocybin | 002 5件: 2 , 6 , 13, 149, 206 💬47. Neuroactive ligand-receptor interaction |
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| 48 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
MTNR1A 2件: MTNR1A, MTNR1B 💬
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Melatonin Melatonin 💬Neuroactive ligand-receptor interaction
| Melatonin | 002 18件: 2 , 6 , 8 , 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬48. Neuroactive ligand-receptor interaction
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| 49 | NF-kappa B signaling pathway 💬 23 genes, 81 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬NF-kappa B signaling pathway
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Anakinra Anakinra 💬NF-kappa B signaling pathway
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬49. NF-kappa B signaling pathway
|
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| 50 | Non-alcoholic fatty liver disease 💬 24 genes, 54 drugs (DrugBank) and 100 diseases |
IL6R 1件: IL6R 💬Non-alcoholic fatty liver disease
|
Tocilizumab Tocilizumab 💬Non-alcoholic fatty liver disease
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬50. Non-alcoholic fatty liver disease
|
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| 51 | Osteoclast differentiation 💬 40 genes, 93 drugs (DrugBank) and 109 diseases |
IL1R1 1件: IL1R1 💬Osteoclast differentiation
|
Anakinra Anakinra 💬Osteoclast differentiation
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬51. Osteoclast differentiation
|
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| 52 | Pathogenic Escherichia coli infection 💬 31 genes, 46 drugs (DrugBank) and 84 diseases |
IL1R1 1件: IL1R1 💬Pathogenic Escherichia coli infection
|
Anakinra Anakinra 💬Pathogenic Escherichia coli infection
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬52. Pathogenic Escherichia coli infection
|
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| 53 | Pathways in cancer 💬 116 genes, 235 drugs (DrugBank) and 150 diseases |
IL6R 1件: IL6R 💬Pathways in cancer
|
Tocilizumab Tocilizumab 💬Pathways in cancer
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬53. Pathways in cancer
|
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| 54 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
SIGMAR1 1件: SIGMAR1 💬Pathways of neurodegeneration - multiple diseases
|
Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Pathways of neurodegeneration - multiple diseases
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬54. Pathways of neurodegeneration - multiple diseases |
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| 55 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
SIGMAR1 1件: SIGMAR1 💬Pathways of neurodegeneration - multiple diseases
|
Fenfluramine Fenfluramine 💬Pathways of neurodegeneration - multiple diseases
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬54. Pathways of neurodegeneration - multiple diseases |
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| 56 | PI3K-Akt signaling pathway 💬 86 genes, 147 drugs (DrugBank) and 129 diseases |
IL6R 1件: IL6R 💬PI3K-Akt signaling pathway
|
Tocilizumab Tocilizumab 💬PI3K-Akt signaling pathway
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬56. PI3K-Akt signaling pathway
|
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| 57 | Prostate cancer 💬 24 genes, 58 drugs (DrugBank) and 92 diseases |
IL1R2 1件: IL1R2 💬Prostate cancer
|
Anakinra Anakinra 💬Prostate cancer
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬57. Prostate cancer
|
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| 58 | Serotonergic synapse 💬 40 genes, 130 drugs (DrugBank) and 89 diseases |
HTR1D 4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬
|
Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Serotonergic synapse
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬58. Serotonergic synapse |
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| 59 | Serotonergic synapse 💬 40 genes, 130 drugs (DrugBank) and 89 diseases |
HTR1D 4件: HTR1D, HTR2A, HTR2C, SLC6A4 💬
|
Fenfluramine Fenfluramine 💬Serotonergic synapse
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬58. Serotonergic synapse |
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| 60 | Serotonergic synapse 💬 40 genes, 130 drugs (DrugBank) and 89 diseases |
HTR2A 1件: HTR2A 💬Serotonergic synapse
|
Psilocybin Psilocybin 💬Serotonergic synapse
| Psilocybin | 002 5件: 2 , 6 , 13, 149, 206 💬60. Serotonergic synapse |
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| 61 | Shigellosis 💬 31 genes, 54 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬Shigellosis
|
Anakinra Anakinra 💬Shigellosis
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬61. Shigellosis
|
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| 62 | Synaptic vesicle cycle 💬 8 genes, 32 drugs (DrugBank) and 43 diseases |
SLC6A4 1件: SLC6A4 💬Synaptic vesicle cycle
|
Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Synaptic vesicle cycle
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬62. Synaptic vesicle cycle |
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| 63 | Synaptic vesicle cycle 💬 8 genes, 32 drugs (DrugBank) and 43 diseases |
SLC6A4 1件: SLC6A4 💬Synaptic vesicle cycle
|
Fenfluramine Fenfluramine 💬Synaptic vesicle cycle
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬62. Synaptic vesicle cycle |
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| 64 | Synaptic vesicle cycle 💬 8 genes, 32 drugs (DrugBank) and 43 diseases |
SNAP25 1件: SNAP25 💬Synaptic vesicle cycle
|
Botulinum toxin type A Botulinum toxin type A 💬Synaptic vesicle cycle
| Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬64. Synaptic vesicle cycle
|
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| 65 | Synaptic vesicle cycle 💬 8 genes, 32 drugs (DrugBank) and 43 diseases |
SNAP25 1件: SNAP25 💬Synaptic vesicle cycle
|
Incobotulinumtoxin A Incobotulinumtoxin A 💬Synaptic vesicle cycle
| Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 47, 70, 113, 149, 171, 226 💬64. Synaptic vesicle cycle
|
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| 66 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
GABBR1 2件: GABBR1, GABBR2 💬
|
Baclofen Baclofen 💬Taste transduction
| Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬66. Taste transduction
|
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| 67 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
HTR1D 1件: HTR1D 💬Taste transduction
|
Fenfluramine hydrochloride Fenfluramine hydrochloride 💬Taste transduction
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬
|
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| 68 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
HTR1D 1件: HTR1D 💬Taste transduction
|
Fenfluramine Fenfluramine 💬Taste transduction
| Fenfluramine | 140 6件: 140, 143, 144, 145, 149, 156 💬
|
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| 69 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
SCN3A 2件: SCN3A, SCN9A 💬
|
Lacosamide Lacosamide 💬Taste transduction
| Lacosamide | 002 4件: 2 , 46, 149, 298 💬
|
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| 70 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
IL1R1 1件: IL1R1 💬Th17 cell differentiation
|
Anakinra Anakinra 💬Th17 cell differentiation
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬70. Th17 cell differentiation
|
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| 71 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
IL6R 1件: IL6R 💬Th17 cell differentiation
|
Tocilizumab Tocilizumab 💬Th17 cell differentiation
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬71. Th17 cell differentiation
|
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| 72 | Transcriptional misregulation in cancer 💬 28 genes, 64 drugs (DrugBank) and 83 diseases |
IL1R2 1件: IL1R2 💬Transcriptional misregulation in cancer
|
Anakinra Anakinra 💬Transcriptional misregulation in cancer
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬72. Transcriptional misregulation in cancer
|
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| 73 | Viral protein interaction with cytokine and cytokine receptor 💬 18 genes, 31 drugs (DrugBank) and 68 diseases |
IL6R 1件: IL6R 💬Viral protein interaction with cytokine and cytokine receptor
|
Tocilizumab Tocilizumab 💬Viral protein interaction with cytokine and cytokine receptor
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬73. Viral protein interaction with cytokine and cytokine receptor
|
Amoebiasis
20 genes, 32 drugs (DrugBank) and 77 diseases
Amyotrophic lateral sclerosis
39 genes, 58 drugs (DrugBank) and 116 diseases
Calcium signaling pathway
82 genes, 215 drugs (DrugBank) and 140 diseases
cAMP signaling pathway
67 genes, 191 drugs (DrugBank) and 133 diseases
Circadian entrainment
22 genes, 42 drugs (DrugBank) and 62 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Cytokine-cytokine receptor interaction
90 genes, 141 drugs (DrugBank) and 104 diseases
ECM-receptor interaction
9 genes, 11 drugs (DrugBank) and 16 diseases
Estrogen signaling pathway
20 genes, 80 drugs (DrugBank) and 70 diseases
Fat digestion and absorption
3 genes, 3 drugs (DrugBank) and 5 diseases
Fluid shear stress and atherosclerosis
33 genes, 60 drugs (DrugBank) and 100 diseases
GABAergic synapse
29 genes, 42 drugs (DrugBank) and 57 diseases
Gap junction
27 genes, 103 drugs (DrugBank) and 87 diseases
GnRH secretion
27 genes, 49 drugs (DrugBank) and 62 diseases
Hematopoietic cell lineage
47 genes, 97 drugs (DrugBank) and 101 diseases
HIF-1 signaling pathway
26 genes, 56 drugs (DrugBank) and 87 diseases
Human cytomegalovirus infection
65 genes, 121 drugs (DrugBank) and 136 diseases
Human T-cell leukemia virus 1 infection
61 genes, 80 drugs (DrugBank) and 105 diseases
Inflammatory mediator regulation of TRP channels
26 genes, 55 drugs (DrugBank) and 70 diseases
Insulin secretion
16 genes, 51 drugs (DrugBank) and 61 diseases
JAK-STAT signaling pathway
60 genes, 117 drugs (DrugBank) and 116 diseases
MAPK signaling pathway
70 genes, 101 drugs (DrugBank) and 117 diseases
Morphine addiction
43 genes, 70 drugs (DrugBank) and 80 diseases
Neuroactive ligand signaling
92 genes, 239 drugs (DrugBank) and 118 diseases
Neuroactive ligand-receptor interaction
156 genes, 371 drugs (DrugBank) and 171 diseases
NF-kappa B signaling pathway
23 genes, 81 drugs (DrugBank) and 97 diseases
Non-alcoholic fatty liver disease
24 genes, 54 drugs (DrugBank) and 100 diseases
Osteoclast differentiation
40 genes, 93 drugs (DrugBank) and 109 diseases
Pathogenic Escherichia coli infection
31 genes, 46 drugs (DrugBank) and 84 diseases
Pathways in cancer
116 genes, 235 drugs (DrugBank) and 150 diseases
Pathways of neurodegeneration - multiple diseases
64 genes, 143 drugs (DrugBank) and 141 diseases
PI3K-Akt signaling pathway
86 genes, 147 drugs (DrugBank) and 129 diseases
Prostate cancer
24 genes, 58 drugs (DrugBank) and 92 diseases
Serotonergic synapse
40 genes, 130 drugs (DrugBank) and 89 diseases
Shigellosis
31 genes, 54 drugs (DrugBank) and 97 diseases
Synaptic vesicle cycle
8 genes, 32 drugs (DrugBank) and 43 diseases
Taste transduction
29 genes, 93 drugs (DrugBank) and 78 diseases
Th17 cell differentiation
57 genes, 88 drugs (DrugBank) and 111 diseases
Transcriptional misregulation in cancer
28 genes, 64 drugs (DrugBank) and 83 diseases
Viral protein interaction with cytokine and cytokine receptor
18 genes, 31 drugs (DrugBank) and 68 diseases