Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Amoebiasis 💬 20 genes, 32 drugs (DrugBank) and 77 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Amoebiasis
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬1. Amoebiasis
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| 2 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
IL6R 1件: IL6R 💬Coronavirus disease
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Tocilizumab Tocilizumab 💬Coronavirus disease
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬2. Coronavirus disease
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| 3 | Cytokine-cytokine receptor interaction 💬 90 genes, 141 drugs (DrugBank) and 104 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Cytokine-cytokine receptor interaction
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬3. Cytokine-cytokine receptor interaction
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| 4 | Cytokine-cytokine receptor interaction 💬 90 genes, 141 drugs (DrugBank) and 104 diseases |
IL6R 1件: IL6R 💬Cytokine-cytokine receptor interaction
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Tocilizumab Tocilizumab 💬Cytokine-cytokine receptor interaction
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬4. Cytokine-cytokine receptor interaction
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| 5 | Fluid shear stress and atherosclerosis 💬 33 genes, 60 drugs (DrugBank) and 100 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Fluid shear stress and atherosclerosis
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬5. Fluid shear stress and atherosclerosis
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| 6 | Hematopoietic cell lineage 💬 47 genes, 97 drugs (DrugBank) and 101 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Hematopoietic cell lineage
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬6. Hematopoietic cell lineage
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| 7 | Hematopoietic cell lineage 💬 47 genes, 97 drugs (DrugBank) and 101 diseases |
IL6R 1件: IL6R 💬Hematopoietic cell lineage
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Tocilizumab Tocilizumab 💬Hematopoietic cell lineage
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬7. Hematopoietic cell lineage
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| 8 | HIF-1 signaling pathway 💬 26 genes, 56 drugs (DrugBank) and 87 diseases |
IL6R 1件: IL6R 💬HIF-1 signaling pathway
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Tocilizumab Tocilizumab 💬HIF-1 signaling pathway
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬8. HIF-1 signaling pathway
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| 9 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
IL1R1 1件: IL1R1 💬Human cytomegalovirus infection
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Anakinra Anakinra 💬Human cytomegalovirus infection
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬9. Human cytomegalovirus infection
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| 10 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
IL6R 1件: IL6R 💬Human cytomegalovirus infection
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Tocilizumab Tocilizumab 💬Human cytomegalovirus infection
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬10. Human cytomegalovirus infection
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| 11 | Human T-cell leukemia virus 1 infection 💬 61 genes, 80 drugs (DrugBank) and 105 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
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Anakinra Anakinra 💬Human T-cell leukemia virus 1 infection
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬11. Human T-cell leukemia virus 1 infection
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| 12 | Inflammatory mediator regulation of TRP channels 💬 26 genes, 55 drugs (DrugBank) and 70 diseases |
IL1R1 1件: IL1R1 💬Inflammatory mediator regulation of TRP channels
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Anakinra Anakinra 💬Inflammatory mediator regulation of TRP channels
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬12. Inflammatory mediator regulation of TRP channels
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| 13 | JAK-STAT signaling pathway 💬 60 genes, 117 drugs (DrugBank) and 116 diseases |
IL6R 1件: IL6R 💬JAK-STAT signaling pathway
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Tocilizumab Tocilizumab 💬JAK-STAT signaling pathway
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬13. JAK-STAT signaling pathway
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| 14 | MAPK signaling pathway 💬 70 genes, 101 drugs (DrugBank) and 117 diseases |
IL1R1 1件: IL1R1 💬MAPK signaling pathway
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Anakinra Anakinra 💬MAPK signaling pathway
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬14. MAPK signaling pathway
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| 15 | NF-kappa B signaling pathway 💬 23 genes, 81 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬NF-kappa B signaling pathway
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Anakinra Anakinra 💬NF-kappa B signaling pathway
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬15. NF-kappa B signaling pathway
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| 16 | Non-alcoholic fatty liver disease 💬 24 genes, 54 drugs (DrugBank) and 100 diseases |
IL6R 1件: IL6R 💬Non-alcoholic fatty liver disease
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Tocilizumab Tocilizumab 💬Non-alcoholic fatty liver disease
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬16. Non-alcoholic fatty liver disease
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| 17 | Osteoclast differentiation 💬 40 genes, 93 drugs (DrugBank) and 109 diseases |
IL1R1 1件: IL1R1 💬Osteoclast differentiation
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Anakinra Anakinra 💬Osteoclast differentiation
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬17. Osteoclast differentiation
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| 18 | Pathogenic Escherichia coli infection 💬 31 genes, 46 drugs (DrugBank) and 84 diseases |
IL1R1 1件: IL1R1 💬Pathogenic Escherichia coli infection
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Anakinra Anakinra 💬Pathogenic Escherichia coli infection
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬18. Pathogenic Escherichia coli infection
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| 19 | Pathways in cancer 💬 116 genes, 235 drugs (DrugBank) and 150 diseases |
IL6R 1件: IL6R 💬Pathways in cancer
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Tocilizumab Tocilizumab 💬Pathways in cancer
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬19. Pathways in cancer
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| 20 | PI3K-Akt signaling pathway 💬 86 genes, 147 drugs (DrugBank) and 129 diseases |
IL6R 1件: IL6R 💬PI3K-Akt signaling pathway
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Tocilizumab Tocilizumab 💬PI3K-Akt signaling pathway
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬20. PI3K-Akt signaling pathway
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| 21 | Prostate cancer 💬 24 genes, 58 drugs (DrugBank) and 92 diseases |
IL1R2 1件: IL1R2 💬Prostate cancer
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Anakinra Anakinra 💬Prostate cancer
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬21. Prostate cancer
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| 22 | Shigellosis 💬 31 genes, 54 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬Shigellosis
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Anakinra Anakinra 💬Shigellosis
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬22. Shigellosis
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| 23 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
IL1R1 1件: IL1R1 💬Th17 cell differentiation
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Anakinra Anakinra 💬Th17 cell differentiation
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬23. Th17 cell differentiation
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| 24 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
IL6R 1件: IL6R 💬Th17 cell differentiation
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Tocilizumab Tocilizumab 💬Th17 cell differentiation
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬24. Th17 cell differentiation
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| 25 | Transcriptional misregulation in cancer 💬 28 genes, 64 drugs (DrugBank) and 83 diseases |
IL1R2 1件: IL1R2 💬Transcriptional misregulation in cancer
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Anakinra Anakinra 💬Transcriptional misregulation in cancer
| Anakinra | 002 22件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬25. Transcriptional misregulation in cancer
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| 26 | Viral protein interaction with cytokine and cytokine receptor 💬 18 genes, 31 drugs (DrugBank) and 68 diseases |
IL6R 1件: IL6R 💬Viral protein interaction with cytokine and cytokine receptor
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Tocilizumab Tocilizumab 💬Viral protein interaction with cytokine and cytokine receptor
| Tocilizumab | 002 26件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬26. Viral protein interaction with cytokine and cytokine receptor
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Amoebiasis
20 genes, 32 drugs (DrugBank) and 77 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Cytokine-cytokine receptor interaction
90 genes, 141 drugs (DrugBank) and 104 diseases
Fluid shear stress and atherosclerosis
33 genes, 60 drugs (DrugBank) and 100 diseases
Hematopoietic cell lineage
47 genes, 97 drugs (DrugBank) and 101 diseases
HIF-1 signaling pathway
26 genes, 56 drugs (DrugBank) and 87 diseases
Human cytomegalovirus infection
65 genes, 121 drugs (DrugBank) and 136 diseases
Human T-cell leukemia virus 1 infection
61 genes, 80 drugs (DrugBank) and 105 diseases
Inflammatory mediator regulation of TRP channels
26 genes, 55 drugs (DrugBank) and 70 diseases
JAK-STAT signaling pathway
60 genes, 117 drugs (DrugBank) and 116 diseases
MAPK signaling pathway
70 genes, 101 drugs (DrugBank) and 117 diseases
NF-kappa B signaling pathway
23 genes, 81 drugs (DrugBank) and 97 diseases
Non-alcoholic fatty liver disease
24 genes, 54 drugs (DrugBank) and 100 diseases
Osteoclast differentiation
40 genes, 93 drugs (DrugBank) and 109 diseases
Pathogenic Escherichia coli infection
31 genes, 46 drugs (DrugBank) and 84 diseases
Pathways in cancer
116 genes, 235 drugs (DrugBank) and 150 diseases
PI3K-Akt signaling pathway
86 genes, 147 drugs (DrugBank) and 129 diseases
Prostate cancer
24 genes, 58 drugs (DrugBank) and 92 diseases
Shigellosis
31 genes, 54 drugs (DrugBank) and 97 diseases
Th17 cell differentiation
57 genes, 88 drugs (DrugBank) and 111 diseases
Transcriptional misregulation in cancer
28 genes, 64 drugs (DrugBank) and 83 diseases
Viral protein interaction with cytokine and cytokine receptor
18 genes, 31 drugs (DrugBank) and 68 diseases