Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||
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| 1 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 55 drugs (DrugBank) and 96 diseases |
VEGFA 1件: VEGFA 💬AGE-RAGE signaling pathway in diabetic complications
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Ranibizumab Ranibizumab 💬AGE-RAGE signaling pathway in diabetic complications
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬1. AGE-RAGE signaling pathway in diabetic complications |
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| 2 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 55 drugs (DrugBank) and 96 diseases |
VEGFA 2件: VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬AGE-RAGE signaling pathway in diabetic complications
| Aflibercept | 090 2件: 90, 166 💬
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| 3 | Bladder cancer 💬 11 genes, 27 drugs (DrugBank) and 33 diseases |
VEGFA 1件: VEGFA 💬Bladder cancer
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Aflibercept Aflibercept 💬Bladder cancer
| Aflibercept | 090 2件: 90, 166 💬
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| 4 | Bladder cancer 💬 11 genes, 27 drugs (DrugBank) and 33 diseases |
VEGFA 1件: VEGFA 💬Bladder cancer
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Ranibizumab Ranibizumab 💬Bladder cancer
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 5 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
VEGFA 1件: VEGFA 💬Calcium signaling pathway
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Ranibizumab Ranibizumab 💬Calcium signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 6 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
VEGFA 2件: VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬Calcium signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 7 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 39 drugs (DrugBank) and 51 diseases |
VEGFA 1件: VEGFA 💬Chemical carcinogenesis - reactive oxygen species
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Aflibercept Aflibercept 💬Chemical carcinogenesis - reactive oxygen species
| Aflibercept | 090 2件: 90, 166 💬
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| 8 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 39 drugs (DrugBank) and 51 diseases |
VEGFA 1件: VEGFA 💬Chemical carcinogenesis - reactive oxygen species
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Ranibizumab Ranibizumab 💬Chemical carcinogenesis - reactive oxygen species
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬8. Chemical carcinogenesis - reactive oxygen species |
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| 9 | Chemical carcinogenesis - receptor activation 💬 39 genes, 135 drugs (DrugBank) and 134 diseases |
VEGFA 1件: VEGFA 💬Chemical carcinogenesis - receptor activation
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Aflibercept Aflibercept 💬Chemical carcinogenesis - receptor activation
| Aflibercept | 090 2件: 90, 166 💬
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| 10 | Chemical carcinogenesis - receptor activation 💬 39 genes, 135 drugs (DrugBank) and 134 diseases |
VEGFA 1件: VEGFA 💬Chemical carcinogenesis - receptor activation
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Ranibizumab Ranibizumab 💬Chemical carcinogenesis - receptor activation
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬10. Chemical carcinogenesis - receptor activation |
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| 11 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 34 diseases |
ATP4A 2件: ATP4A, ATP4B 💬
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Lansoprazole Lansoprazole 💬Collecting duct acid secretion
| Lansoprazole | 063 6件: 63, 71, 85, 166, 222, 299 💬11. Collecting duct acid secretion
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| 12 | Fluid shear stress and atherosclerosis 💬 34 genes, 59 drugs (DrugBank) and 93 diseases |
VEGFA 1件: VEGFA 💬Fluid shear stress and atherosclerosis
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Aflibercept Aflibercept 💬Fluid shear stress and atherosclerosis
| Aflibercept | 090 2件: 90, 166 💬
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| 13 | Fluid shear stress and atherosclerosis 💬 34 genes, 59 drugs (DrugBank) and 93 diseases |
VEGFA 1件: VEGFA 💬Fluid shear stress and atherosclerosis
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Ranibizumab Ranibizumab 💬Fluid shear stress and atherosclerosis
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬13. Fluid shear stress and atherosclerosis |
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| 14 | Focal adhesion 💬 31 genes, 51 drugs (DrugBank) and 52 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬Focal adhesion
| Aflibercept | 090 2件: 90, 166 💬
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| 15 | Focal adhesion 💬 31 genes, 51 drugs (DrugBank) and 52 diseases |
VEGFA 1件: VEGFA 💬Focal adhesion
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Ranibizumab Ranibizumab 💬Focal adhesion
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 16 | Gastric acid secretion 💬 14 genes, 55 drugs (DrugBank) and 63 diseases |
ATP4A 2件: ATP4A, ATP4B 💬
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Lansoprazole Lansoprazole 💬Gastric acid secretion
| Lansoprazole | 063 6件: 63, 71, 85, 166, 222, 299 💬16. Gastric acid secretion
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| 17 | HIF-1 signaling pathway 💬 26 genes, 56 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬HIF-1 signaling pathway
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Aflibercept Aflibercept 💬HIF-1 signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 18 | HIF-1 signaling pathway 💬 26 genes, 56 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬HIF-1 signaling pathway
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Ranibizumab Ranibizumab 💬HIF-1 signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 19 | Human cytomegalovirus infection 💬 64 genes, 114 drugs (DrugBank) and 130 diseases |
VEGFA 1件: VEGFA 💬Human cytomegalovirus infection
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Aflibercept Aflibercept 💬Human cytomegalovirus infection
| Aflibercept | 090 2件: 90, 166 💬
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| 20 | Human cytomegalovirus infection 💬 64 genes, 114 drugs (DrugBank) and 130 diseases |
VEGFA 1件: VEGFA 💬Human cytomegalovirus infection
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Ranibizumab Ranibizumab 💬Human cytomegalovirus infection
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬20. Human cytomegalovirus infection |
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| 21 | Human papillomavirus infection 💬 51 genes, 106 drugs (DrugBank) and 115 diseases |
VEGFA 1件: VEGFA 💬Human papillomavirus infection
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Aflibercept Aflibercept 💬Human papillomavirus infection
| Aflibercept | 090 2件: 90, 166 💬
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| 22 | Human papillomavirus infection 💬 51 genes, 106 drugs (DrugBank) and 115 diseases |
VEGFA 1件: VEGFA 💬Human papillomavirus infection
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Ranibizumab Ranibizumab 💬Human papillomavirus infection
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬22. Human papillomavirus infection |
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| 23 | Kaposi sarcoma-associated herpesvirus infection 💬 60 genes, 94 drugs (DrugBank) and 118 diseases |
VEGFA 1件: VEGFA 💬Kaposi sarcoma-associated herpesvirus infection
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Aflibercept Aflibercept 💬Kaposi sarcoma-associated herpesvirus infection
| Aflibercept | 090 2件: 90, 166 💬
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| 24 | Kaposi sarcoma-associated herpesvirus infection 💬 60 genes, 94 drugs (DrugBank) and 118 diseases |
VEGFA 1件: VEGFA 💬Kaposi sarcoma-associated herpesvirus infection
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Ranibizumab Ranibizumab 💬Kaposi sarcoma-associated herpesvirus infection
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬24. Kaposi sarcoma-associated herpesvirus infection |
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| 25 | MAPK signaling pathway 💬 65 genes, 98 drugs (DrugBank) and 109 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬MAPK signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 26 | MAPK signaling pathway 💬 65 genes, 98 drugs (DrugBank) and 109 diseases |
VEGFA 1件: VEGFA 💬MAPK signaling pathway
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Ranibizumab Ranibizumab 💬MAPK signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 27 | MicroRNAs in cancer 💬 33 genes, 75 drugs (DrugBank) and 90 diseases |
VEGFA 1件: VEGFA 💬MicroRNAs in cancer
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Aflibercept Aflibercept 💬MicroRNAs in cancer
| Aflibercept | 090 2件: 90, 166 💬
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| 28 | MicroRNAs in cancer 💬 33 genes, 75 drugs (DrugBank) and 90 diseases |
VEGFA 1件: VEGFA 💬MicroRNAs in cancer
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Ranibizumab Ranibizumab 💬MicroRNAs in cancer
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 29 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 26 diseases |
ATP4A 2件: ATP4A, ATP4B 💬
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Lansoprazole Lansoprazole 💬Oxidative phosphorylation
| Lansoprazole | 063 6件: 63, 71, 85, 166, 222, 299 💬29. Oxidative phosphorylation
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| 30 | Pancreatic cancer 💬 19 genes, 40 drugs (DrugBank) and 84 diseases |
VEGFA 1件: VEGFA 💬Pancreatic cancer
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Aflibercept Aflibercept 💬Pancreatic cancer
| Aflibercept | 090 2件: 90, 166 💬
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| 31 | Pancreatic cancer 💬 19 genes, 40 drugs (DrugBank) and 84 diseases |
VEGFA 1件: VEGFA 💬Pancreatic cancer
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Ranibizumab Ranibizumab 💬Pancreatic cancer
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 32 | Pathways in cancer 💬 111 genes, 222 drugs (DrugBank) and 146 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬Pathways in cancer
| Aflibercept | 090 2件: 90, 166 💬
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| 33 | Pathways in cancer 💬 111 genes, 222 drugs (DrugBank) and 146 diseases |
VEGFA 1件: VEGFA 💬Pathways in cancer
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Ranibizumab Ranibizumab 💬Pathways in cancer
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 34 | PI3K-Akt signaling pathway 💬 85 genes, 142 drugs (DrugBank) and 131 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬PI3K-Akt signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 35 | PI3K-Akt signaling pathway 💬 85 genes, 142 drugs (DrugBank) and 131 diseases |
VEGFA 1件: VEGFA 💬PI3K-Akt signaling pathway
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Ranibizumab Ranibizumab 💬PI3K-Akt signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬35. PI3K-Akt signaling pathway |
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| 36 | Proteoglycans in cancer 💬 33 genes, 73 drugs (DrugBank) and 103 diseases |
VEGFA 1件: VEGFA 💬Proteoglycans in cancer
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Aflibercept Aflibercept 💬Proteoglycans in cancer
| Aflibercept | 090 2件: 90, 166 💬
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| 37 | Proteoglycans in cancer 💬 33 genes, 73 drugs (DrugBank) and 103 diseases |
VEGFA 1件: VEGFA 💬Proteoglycans in cancer
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Ranibizumab Ranibizumab 💬Proteoglycans in cancer
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 38 | Rap1 signaling pathway 💬 45 genes, 113 drugs (DrugBank) and 98 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬Rap1 signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 39 | Rap1 signaling pathway 💬 45 genes, 113 drugs (DrugBank) and 98 diseases |
VEGFA 1件: VEGFA 💬Rap1 signaling pathway
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Ranibizumab Ranibizumab 💬Rap1 signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 40 | Ras signaling pathway 💬 37 genes, 64 drugs (DrugBank) and 70 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬Ras signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 41 | Ras signaling pathway 💬 37 genes, 64 drugs (DrugBank) and 70 diseases |
VEGFA 1件: VEGFA 💬Ras signaling pathway
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Ranibizumab Ranibizumab 💬Ras signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 42 | Relaxin signaling pathway 💬 23 genes, 34 drugs (DrugBank) and 51 diseases |
VEGFA 1件: VEGFA 💬Relaxin signaling pathway
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Ranibizumab Ranibizumab 💬Relaxin signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬42. Relaxin signaling pathway |
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| 43 | Relaxin signaling pathway 💬 23 genes, 34 drugs (DrugBank) and 51 diseases |
VEGFA 2件: VEGFA, VEGFB 💬
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Aflibercept Aflibercept 💬Relaxin signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 44 | Renal cell carcinoma 💬 12 genes, 16 drugs (DrugBank) and 26 diseases |
VEGFA 1件: VEGFA 💬Renal cell carcinoma
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Aflibercept Aflibercept 💬Renal cell carcinoma
| Aflibercept | 090 2件: 90, 166 💬
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| 45 | Renal cell carcinoma 💬 12 genes, 16 drugs (DrugBank) and 26 diseases |
VEGFA 1件: VEGFA 💬Renal cell carcinoma
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Ranibizumab Ranibizumab 💬Renal cell carcinoma
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 46 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬Rheumatoid arthritis
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Aflibercept Aflibercept 💬Rheumatoid arthritis
| Aflibercept | 090 2件: 90, 166 💬
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| 47 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬Rheumatoid arthritis
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Ranibizumab Ranibizumab 💬Rheumatoid arthritis
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 48 | VEGF signaling pathway 💬 23 genes, 56 drugs (DrugBank) and 94 diseases |
VEGFA 1件: VEGFA 💬VEGF signaling pathway
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Aflibercept Aflibercept 💬VEGF signaling pathway
| Aflibercept | 090 2件: 90, 166 💬
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| 49 | VEGF signaling pathway 💬 23 genes, 56 drugs (DrugBank) and 94 diseases |
VEGFA 1件: VEGFA 💬VEGF signaling pathway
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Ranibizumab Ranibizumab 💬VEGF signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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AGE-RAGE signaling pathway in diabetic complications
28 genes, 55 drugs (DrugBank) and 96 diseases
Bladder cancer
11 genes, 27 drugs (DrugBank) and 33 diseases
Calcium signaling pathway
86 genes, 214 drugs (DrugBank) and 143 diseases
Chemical carcinogenesis - reactive oxygen species
25 genes, 39 drugs (DrugBank) and 51 diseases
Chemical carcinogenesis - receptor activation
39 genes, 135 drugs (DrugBank) and 134 diseases
Collecting duct acid secretion
3 genes, 11 drugs (DrugBank) and 34 diseases
Fluid shear stress and atherosclerosis
34 genes, 59 drugs (DrugBank) and 93 diseases
Focal adhesion
31 genes, 51 drugs (DrugBank) and 52 diseases
Gastric acid secretion
14 genes, 55 drugs (DrugBank) and 63 diseases
HIF-1 signaling pathway
26 genes, 56 drugs (DrugBank) and 87 diseases
Human cytomegalovirus infection
64 genes, 114 drugs (DrugBank) and 130 diseases
Human papillomavirus infection
51 genes, 106 drugs (DrugBank) and 115 diseases
Kaposi sarcoma-associated herpesvirus infection
60 genes, 94 drugs (DrugBank) and 118 diseases
MAPK signaling pathway
65 genes, 98 drugs (DrugBank) and 109 diseases
MicroRNAs in cancer
33 genes, 75 drugs (DrugBank) and 90 diseases
Oxidative phosphorylation
2 genes, 7 drugs (DrugBank) and 26 diseases
Pancreatic cancer
19 genes, 40 drugs (DrugBank) and 84 diseases
Pathways in cancer
111 genes, 222 drugs (DrugBank) and 146 diseases
PI3K-Akt signaling pathway
85 genes, 142 drugs (DrugBank) and 131 diseases
Proteoglycans in cancer
33 genes, 73 drugs (DrugBank) and 103 diseases
Rap1 signaling pathway
45 genes, 113 drugs (DrugBank) and 98 diseases
Ras signaling pathway
37 genes, 64 drugs (DrugBank) and 70 diseases
Relaxin signaling pathway
23 genes, 34 drugs (DrugBank) and 51 diseases
Renal cell carcinoma
12 genes, 16 drugs (DrugBank) and 26 diseases
Rheumatoid arthritis
38 genes, 59 drugs (DrugBank) and 87 diseases
VEGF signaling pathway
23 genes, 56 drugs (DrugBank) and 94 diseases