Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alzheimer disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
2 Amyotrophic lateral sclerosis 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
3 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
4 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: PTH1R 💬 Teriparatide 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
5 Endocrine and other factor-regulated calcium reabsorption 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
6 Folate biosynthesis 💬
 1件: ALPL 💬 Asfotase alfa 💬 Asfotase alfa 1件: 172 💬
7 Folate biosynthesis 💬
 2件: DHFR, DHFR2 💬 Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
8 Folate biosynthesis 💬
 2件: DHFR, DHFR2 💬 Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
9 Folate transport and metabolism 💬
 2件: DHFR, DHFR2 💬 Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
10 Folate transport and metabolism 💬
 2件: DHFR, DHFR2 💬 Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
11 Hematopoietic cell lineage 💬
 1件: MS4A1 💬 Rituximab 💬 Rituximab 54件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
12 Hormone signaling 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
13 Hormone signaling 💬
 1件: PTH1R 💬 Teriparatide 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
14 Hormone signaling 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
15 Huntington disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
16 Neuroactive ligand-receptor interaction 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
17 Neuroactive ligand-receptor interaction 💬
 1件: PTH1R 💬 Teriparatide 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
18 Neuroactive ligand-receptor interaction 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
19 One carbon pool by folate 💬
 2件: DHFR, DHFR2 💬 Methotrexate 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
20 One carbon pool by folate 💬
 2件: DHFR, DHFR2 💬 Methotrexate sodium 💬 Methotrexate 41件: 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
21 Parathyroid hormone synthesis, secretion and action 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
22 Parathyroid hormone synthesis, secretion and action 💬
 1件: PTH1R 💬 Teriparatide 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
23 Parathyroid hormone synthesis, secretion and action 💬
 1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 7件: 46, 68, 70, 71, 172, 235, 274 💬
24 Parkinson disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
25 Pathways of neurodegeneration - multiple diseases 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
26 Phagocytosis 💬
 1件: ALPL 💬 Asfotase alfa 💬 Asfotase alfa 1件: 172 💬
27 Prion disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
28 Proteasome 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
29 Spinocerebellar ataxia 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 19件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
30 Thiamine metabolism 💬
 1件: ALPL 💬 Asfotase alfa 💬 Asfotase alfa 1件: 172 💬

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