Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Alcoholism 💬 29 genes, 80 drugs (DrugBank) and 63 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Alcoholism
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Riluzole Riluzole 💬Alcoholism
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬1. Alcoholism
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| 2 | Alzheimer disease 💬 59 genes, 136 drugs (DrugBank) and 139 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Alzheimer disease
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Riluzole Riluzole 💬Alzheimer disease
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬2. Alzheimer disease
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| 3 | Amphetamine addiction 💬 25 genes, 58 drugs (DrugBank) and 92 diseases |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Amphetamine addiction
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Riluzole Riluzole 💬Amphetamine addiction
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬3. Amphetamine addiction
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| 4 | Amyotrophic lateral sclerosis 💬 39 genes, 58 drugs (DrugBank) and 116 diseases |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Amyotrophic lateral sclerosis
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Riluzole Riluzole 💬Amyotrophic lateral sclerosis
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬4. Amyotrophic lateral sclerosis
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| 5 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Calcium signaling pathway
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Riluzole Riluzole 💬Calcium signaling pathway
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬5. Calcium signaling pathway
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| 6 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬cAMP signaling pathway
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Riluzole Riluzole 💬cAMP signaling pathway
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬6. cAMP signaling pathway
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| 7 | Circadian entrainment 💬 22 genes, 42 drugs (DrugBank) and 62 diseases |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Circadian entrainment
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Riluzole Riluzole 💬Circadian entrainment
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬7. Circadian entrainment
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| 8 | Cocaine addiction 💬 15 genes, 67 drugs (DrugBank) and 58 diseases |
GRIA2 6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Cocaine addiction
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Riluzole Riluzole 💬Cocaine addiction
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬8. Cocaine addiction
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| 9 | Dopaminergic synapse 💬 33 genes, 105 drugs (DrugBank) and 105 diseases |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬Dopaminergic synapse
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Riluzole Riluzole 💬Dopaminergic synapse
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬9. Dopaminergic synapse
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| 10 | Glutamatergic synapse 💬 23 genes, 32 drugs (DrugBank) and 82 diseases |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Glutamatergic synapse
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Riluzole Riluzole 💬Glutamatergic synapse
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬10. Glutamatergic synapse
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| 11 | Huntington disease 💬 26 genes, 42 drugs (DrugBank) and 91 diseases |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬Huntington disease
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Riluzole Riluzole 💬Huntington disease
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬11. Huntington disease
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| 12 | Long-term depression 💬 13 genes, 24 drugs (DrugBank) and 36 diseases |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬
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Riluzole Riluzole 💬Long-term depression
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬12. Long-term depression
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| 13 | Long-term potentiation 💬 18 genes, 37 drugs (DrugBank) and 87 diseases |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Long-term potentiation
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Riluzole Riluzole 💬Long-term potentiation
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬13. Long-term potentiation
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| 14 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Neuroactive ligand signaling
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Riluzole Riluzole 💬Neuroactive ligand signaling
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬14. Neuroactive ligand signaling
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| 15 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Neuroactive ligand-receptor interaction
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Riluzole Riluzole 💬Neuroactive ligand-receptor interaction
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬15. Neuroactive ligand-receptor interaction
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| 16 | Nicotine addiction 💬 30 genes, 37 drugs (DrugBank) and 48 diseases |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Nicotine addiction
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Riluzole Riluzole 💬Nicotine addiction
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬16. Nicotine addiction
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| 17 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Pathways of neurodegeneration - multiple diseases
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Riluzole Riluzole 💬Pathways of neurodegeneration - multiple diseases
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬17. Pathways of neurodegeneration - multiple diseases
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| 18 | Prion disease 💬 41 genes, 77 drugs (DrugBank) and 121 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Prion disease
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Riluzole Riluzole 💬Prion disease
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬18. Prion disease
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| 19 | Rap1 signaling pathway 💬 47 genes, 115 drugs (DrugBank) and 101 diseases |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬
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Riluzole Riluzole 💬Rap1 signaling pathway
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬19. Rap1 signaling pathway
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| 20 | Ras signaling pathway 💬 38 genes, 65 drugs (DrugBank) and 77 diseases |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬
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Riluzole Riluzole 💬Ras signaling pathway
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬20. Ras signaling pathway
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| 21 | Retrograde endocannabinoid signaling 💬 34 genes, 70 drugs (DrugBank) and 74 diseases |
GRIA1 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬
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Riluzole Riluzole 💬Retrograde endocannabinoid signaling
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬21. Retrograde endocannabinoid signaling
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| 22 | Spinocerebellar ataxia 💬 18 genes, 30 drugs (DrugBank) and 79 diseases |
GRIA1 8件: GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬Spinocerebellar ataxia
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Riluzole Riluzole 💬Spinocerebellar ataxia
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬22. Spinocerebellar ataxia
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| 23 | Systemic lupus erythematosus 💬 30 genes, 49 drugs (DrugBank) and 90 diseases |
GRIN2A 2件: GRIN2A, GRIN2B 💬
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Riluzole Riluzole 💬Systemic lupus erythematosus
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬23. Systemic lupus erythematosus
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| 24 | Transcriptional misregulation in cancer 💬 28 genes, 64 drugs (DrugBank) and 83 diseases |
GRIA3 1件: GRIA3 💬Transcriptional misregulation in cancer
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Riluzole Riluzole 💬Transcriptional misregulation in cancer
| Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬24. Transcriptional misregulation in cancer
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Alcoholism
29 genes, 80 drugs (DrugBank) and 63 diseases
Alzheimer disease
59 genes, 136 drugs (DrugBank) and 139 diseases
Amphetamine addiction
25 genes, 58 drugs (DrugBank) and 92 diseases
Amyotrophic lateral sclerosis
39 genes, 58 drugs (DrugBank) and 116 diseases
Calcium signaling pathway
82 genes, 215 drugs (DrugBank) and 140 diseases
cAMP signaling pathway
67 genes, 191 drugs (DrugBank) and 133 diseases
Circadian entrainment
22 genes, 42 drugs (DrugBank) and 62 diseases
Cocaine addiction
15 genes, 67 drugs (DrugBank) and 58 diseases
Dopaminergic synapse
33 genes, 105 drugs (DrugBank) and 105 diseases
Glutamatergic synapse
23 genes, 32 drugs (DrugBank) and 82 diseases
Huntington disease
26 genes, 42 drugs (DrugBank) and 91 diseases
Long-term depression
13 genes, 24 drugs (DrugBank) and 36 diseases
Long-term potentiation
18 genes, 37 drugs (DrugBank) and 87 diseases
Neuroactive ligand signaling
92 genes, 239 drugs (DrugBank) and 118 diseases
Neuroactive ligand-receptor interaction
156 genes, 371 drugs (DrugBank) and 171 diseases
Nicotine addiction
30 genes, 37 drugs (DrugBank) and 48 diseases
Pathways of neurodegeneration - multiple diseases
64 genes, 143 drugs (DrugBank) and 141 diseases
Prion disease
41 genes, 77 drugs (DrugBank) and 121 diseases
Rap1 signaling pathway
47 genes, 115 drugs (DrugBank) and 101 diseases
Ras signaling pathway
38 genes, 65 drugs (DrugBank) and 77 diseases
Retrograde endocannabinoid signaling
34 genes, 70 drugs (DrugBank) and 74 diseases
Spinocerebellar ataxia
18 genes, 30 drugs (DrugBank) and 79 diseases
Systemic lupus erythematosus
30 genes, 49 drugs (DrugBank) and 90 diseases
Transcriptional misregulation in cancer
28 genes, 64 drugs (DrugBank) and 83 diseases