Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 2 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 3 | cAMP signaling pathway 💬 66 genes, 189 drugs (DrugBank) and 130 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 4 | cAMP signaling pathway 💬 66 genes, 189 drugs (DrugBank) and 130 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 5 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 6 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 7 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 8 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 9 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
PDE5 1件: PDE5 💬
|
Sildenafil citrate Sildenafil citrate 💬
| Sildenafil | 006 14件: 6 , 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
|
| 10 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
PDE5 1件: PDE5 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 14件: 6 , 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
|
| 11 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 12 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 13 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
THRA 2件: THRA, THRB 💬
|
Liothyronine sodium Liothyronine sodium 💬
| Liothyronine | 013 3件: 13, 210, 212 💬
|
| 14 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
THRA 2件: THRA, THRB 💬
|
Liothyronine Liothyronine 💬
| Liothyronine | 013 3件: 13, 210, 212 💬
|
| 15 | Melanogenesis 💬 7 genes, 19 drugs (DrugBank) and 34 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 16 | Melanogenesis 💬 7 genes, 19 drugs (DrugBank) and 34 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 17 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 117 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 18 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 117 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 19 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 20 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine hydrochloride Dexmedetomidine hydrochloride 💬
| Dexmedetomidine | 002 15件: 2 , 4 , 6 , 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 21 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 22 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 23 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
THRA 2件: THRA, THRB 💬
|
Liothyronine sodium Liothyronine sodium 💬
| Liothyronine | 013 3件: 13, 210, 212 💬
|
| 24 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
THRA 2件: THRA, THRB 💬
|
Liothyronine Liothyronine 💬
| Liothyronine | 013 3件: 13, 210, 212 💬
|
| 25 | Pathways in cancer 💬 111 genes, 222 drugs (DrugBank) and 146 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 26 | Pathways in cancer 💬 111 genes, 222 drugs (DrugBank) and 146 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 27 | Purine metabolism 💬 30 genes, 40 drugs (DrugBank) and 73 diseases |
PDE5 1件: PDE5 💬
|
Sildenafil citrate Sildenafil citrate 💬
| Sildenafil | 006 14件: 6 , 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
|
| 28 | Purine metabolism 💬 30 genes, 40 drugs (DrugBank) and 73 diseases |
PDE5 1件: PDE5 💬
|
Sildenafil Sildenafil 💬
| Sildenafil | 006 14件: 6 , 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
|
| 29 | Relaxin signaling pathway 💬 23 genes, 34 drugs (DrugBank) and 51 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 30 | Relaxin signaling pathway 💬 23 genes, 34 drugs (DrugBank) and 51 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 31 | Renin secretion 💬 28 genes, 87 drugs (DrugBank) and 113 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 32 | Renin secretion 💬 28 genes, 87 drugs (DrugBank) and 113 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 33 | Thyroid hormone signaling pathway 💬 25 genes, 45 drugs (DrugBank) and 73 diseases |
THRA 2件: THRA, THRB 💬
|
Liothyronine sodium Liothyronine sodium 💬
| Liothyronine | 013 3件: 13, 210, 212 💬
|
| 34 | Thyroid hormone signaling pathway 💬 25 genes, 45 drugs (DrugBank) and 73 diseases |
THRA 2件: THRA, THRB 💬
|
Liothyronine Liothyronine 💬
| Liothyronine | 013 3件: 13, 210, 212 💬
|
| 35 | Vascular smooth muscle contraction 💬 32 genes, 92 drugs (DrugBank) and 71 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
| 36 | Vascular smooth muscle contraction 💬 32 genes, 92 drugs (DrugBank) and 71 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 040 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|