Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Breast cancer 💬 22 genes, 63 drugs (DrugBank) and 80 diseases |
FGF23 1件: FGF23 💬Breast cancer
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Burosumab Burosumab 💬Breast cancer
| Burosumab | 238 1件: 238 💬1. Breast cancer
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| 2 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
FGF23 1件: FGF23 💬Calcium signaling pathway
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Burosumab Burosumab 💬Calcium signaling pathway
| Burosumab | 238 1件: 238 💬2. Calcium signaling pathway
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| 3 | cAMP signaling pathway 💬 66 genes, 189 drugs (DrugBank) and 130 diseases |
SSTR2 1件: SSTR2 💬cAMP signaling pathway
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Edotreotide gallium Ga-68 Edotreotide gallium Ga-68 💬cAMP signaling pathway
| Dotatate gallium Ga-68 | 019 4件: 19, 75, 84, 238 💬3. cAMP signaling pathway
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| 4 | Chemical carcinogenesis - receptor activation 💬 39 genes, 135 drugs (DrugBank) and 134 diseases |
VDR 1件: VDR 💬Chemical carcinogenesis - receptor activation
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Alfacalcidol Alfacalcidol 💬Chemical carcinogenesis - receptor activation
| Alfacalcidol | 041 7件: 41, 46, 50, 96, 107, 235, 238 💬4. Chemical carcinogenesis - receptor activation
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| 5 | Chemical carcinogenesis - receptor activation 💬 39 genes, 135 drugs (DrugBank) and 134 diseases |
VDR 1件: VDR 💬Chemical carcinogenesis - receptor activation
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Paricalcitol Paricalcitol 💬Chemical carcinogenesis - receptor activation
| Paricalcitol | 019 5件: 19, 66, 218, 238, 298 💬5. Chemical carcinogenesis - receptor activation
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| 6 | Cytokine-cytokine receptor interaction 💬 89 genes, 142 drugs (DrugBank) and 110 diseases |
GHR 1件: GHR 💬Cytokine-cytokine receptor interaction
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Somatropin Somatropin 💬Cytokine-cytokine receptor interaction
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬6. Cytokine-cytokine receptor interaction
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| 7 | Endocrine and other factor-regulated calcium reabsorption 💬 9 genes, 29 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬Endocrine and other factor-regulated calcium reabsorption
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Alfacalcidol Alfacalcidol 💬Endocrine and other factor-regulated calcium reabsorption
| Alfacalcidol | 041 7件: 41, 46, 50, 96, 107, 235, 238 💬7. Endocrine and other factor-regulated calcium reabsorption
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| 8 | Endocrine and other factor-regulated calcium reabsorption 💬 9 genes, 29 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬Endocrine and other factor-regulated calcium reabsorption
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Paricalcitol Paricalcitol 💬Endocrine and other factor-regulated calcium reabsorption
| Paricalcitol | 019 5件: 19, 66, 218, 238, 298 💬8. Endocrine and other factor-regulated calcium reabsorption
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| 9 | Gastric acid secretion 💬 14 genes, 55 drugs (DrugBank) and 63 diseases |
SSTR2 1件: SSTR2 💬Gastric acid secretion
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Edotreotide gallium Ga-68 Edotreotide gallium Ga-68 💬Gastric acid secretion
| Dotatate gallium Ga-68 | 019 4件: 19, 75, 84, 238 💬9. Gastric acid secretion
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| 10 | Gastric cancer 💬 22 genes, 40 drugs (DrugBank) and 66 diseases |
FGF23 1件: FGF23 💬Gastric cancer
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Burosumab Burosumab 💬Gastric cancer
| Burosumab | 238 1件: 238 💬10. Gastric cancer
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| 11 | Growth hormone synthesis, secretion and action 💬 23 genes, 49 drugs (DrugBank) and 100 diseases |
GHR 1件: GHR 💬Growth hormone synthesis, secretion and action
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Somatropin Somatropin 💬Growth hormone synthesis, secretion and action
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬11. Growth hormone synthesis, secretion and action
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| 12 | Growth hormone synthesis, secretion and action 💬 23 genes, 49 drugs (DrugBank) and 100 diseases |
SSTR2 1件: SSTR2 💬Growth hormone synthesis, secretion and action
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Edotreotide gallium Ga-68 Edotreotide gallium Ga-68 💬Growth hormone synthesis, secretion and action
| Dotatate gallium Ga-68 | 019 4件: 19, 75, 84, 238 💬12. Growth hormone synthesis, secretion and action
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| 13 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
GHR 1件: GHR 💬Hormone signaling
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Somatropin Somatropin 💬Hormone signaling
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬13. Hormone signaling
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| 14 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
SSTR2 1件: SSTR2 💬Hormone signaling
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Edotreotide gallium Ga-68 Edotreotide gallium Ga-68 💬Hormone signaling
| Dotatate gallium Ga-68 | 019 4件: 19, 75, 84, 238 💬14. Hormone signaling
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| 15 | JAK-STAT signaling pathway 💬 61 genes, 113 drugs (DrugBank) and 123 diseases |
GHR 1件: GHR 💬JAK-STAT signaling pathway
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Somatropin Somatropin 💬JAK-STAT signaling pathway
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬15. JAK-STAT signaling pathway
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| 16 | MAPK signaling pathway 💬 65 genes, 98 drugs (DrugBank) and 109 diseases |
FGF23 1件: FGF23 💬MAPK signaling pathway
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Burosumab Burosumab 💬MAPK signaling pathway
| Burosumab | 238 1件: 238 💬16. MAPK signaling pathway
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| 17 | Melanoma 💬 17 genes, 34 drugs (DrugBank) and 42 diseases |
FGF23 1件: FGF23 💬Melanoma
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Burosumab Burosumab 💬Melanoma
| Burosumab | 238 1件: 238 💬17. Melanoma
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| 18 | Mineral absorption 💬 10 genes, 14 drugs (DrugBank) and 41 diseases |
VDR 1件: VDR 💬Mineral absorption
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Alfacalcidol Alfacalcidol 💬Mineral absorption
| Alfacalcidol | 041 7件: 41, 46, 50, 96, 107, 235, 238 💬18. Mineral absorption
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| 19 | Mineral absorption 💬 10 genes, 14 drugs (DrugBank) and 41 diseases |
VDR 1件: VDR 💬Mineral absorption
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Paricalcitol Paricalcitol 💬Mineral absorption
| Paricalcitol | 019 5件: 19, 66, 218, 238, 298 💬19. Mineral absorption
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| 20 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
GHR 1件: GHR 💬Neuroactive ligand-receptor interaction
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Somatropin Somatropin 💬Neuroactive ligand-receptor interaction
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬20. Neuroactive ligand-receptor interaction
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| 21 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
SSTR2 1件: SSTR2 💬Neuroactive ligand-receptor interaction
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Edotreotide gallium Ga-68 Edotreotide gallium Ga-68 💬Neuroactive ligand-receptor interaction
| Dotatate gallium Ga-68 | 019 4件: 19, 75, 84, 238 💬21. Neuroactive ligand-receptor interaction
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| 22 | NOD-like receptor signaling pathway 💬 32 genes, 51 drugs (DrugBank) and 74 diseases |
CASR 1件: CASR 💬NOD-like receptor signaling pathway
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Cinacalcet Cinacalcet 💬NOD-like receptor signaling pathway
| Cinacalcet | 238 1件: 238 💬22. NOD-like receptor signaling pathway
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| 23 | NOD-like receptor signaling pathway 💬 32 genes, 51 drugs (DrugBank) and 74 diseases |
CASR 1件: CASR 💬NOD-like receptor signaling pathway
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Cinacalcet hydrochloride Cinacalcet hydrochloride 💬NOD-like receptor signaling pathway
| Cinacalcet | 238 1件: 238 💬22. NOD-like receptor signaling pathway
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| 24 | Parathyroid hormone synthesis, secretion and action 💬 22 genes, 58 drugs (DrugBank) and 72 diseases |
CASR 1件: CASR 💬Parathyroid hormone synthesis, secretion and action
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Cinacalcet Cinacalcet 💬Parathyroid hormone synthesis, secretion and action
| Cinacalcet | 238 1件: 238 💬24. Parathyroid hormone synthesis, secretion and action
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| 25 | Parathyroid hormone synthesis, secretion and action 💬 22 genes, 58 drugs (DrugBank) and 72 diseases |
CASR 1件: CASR 💬Parathyroid hormone synthesis, secretion and action
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Cinacalcet hydrochloride Cinacalcet hydrochloride 💬Parathyroid hormone synthesis, secretion and action
| Cinacalcet | 238 1件: 238 💬24. Parathyroid hormone synthesis, secretion and action
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| 26 | Parathyroid hormone synthesis, secretion and action 💬 22 genes, 58 drugs (DrugBank) and 72 diseases |
FGF23 1件: FGF23 💬Parathyroid hormone synthesis, secretion and action
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Burosumab Burosumab 💬Parathyroid hormone synthesis, secretion and action
| Burosumab | 238 1件: 238 💬26. Parathyroid hormone synthesis, secretion and action
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| 27 | Parathyroid hormone synthesis, secretion and action 💬 22 genes, 58 drugs (DrugBank) and 72 diseases |
VDR 1件: VDR 💬Parathyroid hormone synthesis, secretion and action
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Alfacalcidol Alfacalcidol 💬Parathyroid hormone synthesis, secretion and action
| Alfacalcidol | 041 7件: 41, 46, 50, 96, 107, 235, 238 💬27. Parathyroid hormone synthesis, secretion and action
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| 28 | Parathyroid hormone synthesis, secretion and action 💬 22 genes, 58 drugs (DrugBank) and 72 diseases |
VDR 1件: VDR 💬Parathyroid hormone synthesis, secretion and action
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Paricalcitol Paricalcitol 💬Parathyroid hormone synthesis, secretion and action
| Paricalcitol | 019 5件: 19, 66, 218, 238, 298 💬28. Parathyroid hormone synthesis, secretion and action
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| 29 | Pathways in cancer 💬 111 genes, 222 drugs (DrugBank) and 146 diseases |
FGF23 1件: FGF23 💬Pathways in cancer
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Burosumab Burosumab 💬Pathways in cancer
| Burosumab | 238 1件: 238 💬29. Pathways in cancer
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| 30 | PI3K-Akt signaling pathway 💬 85 genes, 142 drugs (DrugBank) and 131 diseases |
FGF23 1件: FGF23 💬PI3K-Akt signaling pathway
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Burosumab Burosumab 💬PI3K-Akt signaling pathway
| Burosumab | 238 1件: 238 💬30. PI3K-Akt signaling pathway
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| 31 | PI3K-Akt signaling pathway 💬 85 genes, 142 drugs (DrugBank) and 131 diseases |
GHR 1件: GHR 💬PI3K-Akt signaling pathway
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Somatropin Somatropin 💬PI3K-Akt signaling pathway
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬31. PI3K-Akt signaling pathway
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| 32 | Rap1 signaling pathway 💬 45 genes, 113 drugs (DrugBank) and 98 diseases |
FGF23 1件: FGF23 💬Rap1 signaling pathway
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Burosumab Burosumab 💬Rap1 signaling pathway
| Burosumab | 238 1件: 238 💬32. Rap1 signaling pathway
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| 33 | Ras signaling pathway 💬 37 genes, 64 drugs (DrugBank) and 70 diseases |
FGF23 1件: FGF23 💬Ras signaling pathway
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Burosumab Burosumab 💬Ras signaling pathway
| Burosumab | 238 1件: 238 💬33. Ras signaling pathway
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| 34 | Regulation of actin cytoskeleton 💬 35 genes, 82 drugs (DrugBank) and 81 diseases |
FGF23 1件: FGF23 💬Regulation of actin cytoskeleton
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Burosumab Burosumab 💬Regulation of actin cytoskeleton
| Burosumab | 238 1件: 238 💬34. Regulation of actin cytoskeleton
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| 35 | Tuberculosis 💬 66 genes, 73 drugs (DrugBank) and 98 diseases |
VDR 1件: VDR 💬Tuberculosis
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Alfacalcidol Alfacalcidol 💬Tuberculosis
| Alfacalcidol | 041 7件: 41, 46, 50, 96, 107, 235, 238 💬35. Tuberculosis
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| 36 | Tuberculosis 💬 66 genes, 73 drugs (DrugBank) and 98 diseases |
VDR 1件: VDR 💬Tuberculosis
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Paricalcitol Paricalcitol 💬Tuberculosis
| Paricalcitol | 019 5件: 19, 66, 218, 238, 298 💬36. Tuberculosis
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Breast cancer
22 genes, 63 drugs (DrugBank) and 80 diseases
Calcium signaling pathway
86 genes, 214 drugs (DrugBank) and 143 diseases
cAMP signaling pathway
66 genes, 189 drugs (DrugBank) and 130 diseases
Chemical carcinogenesis - receptor activation
39 genes, 135 drugs (DrugBank) and 134 diseases
Cytokine-cytokine receptor interaction
89 genes, 142 drugs (DrugBank) and 110 diseases
Endocrine and other factor-regulated calcium reabsorption
9 genes, 29 drugs (DrugBank) and 55 diseases
Gastric acid secretion
14 genes, 55 drugs (DrugBank) and 63 diseases
Gastric cancer
22 genes, 40 drugs (DrugBank) and 66 diseases
Growth hormone synthesis, secretion and action
23 genes, 49 drugs (DrugBank) and 100 diseases
Hormone signaling
66 genes, 211 drugs (DrugBank) and 153 diseases
JAK-STAT signaling pathway
61 genes, 113 drugs (DrugBank) and 123 diseases
MAPK signaling pathway
65 genes, 98 drugs (DrugBank) and 109 diseases
Melanoma
17 genes, 34 drugs (DrugBank) and 42 diseases
Mineral absorption
10 genes, 14 drugs (DrugBank) and 41 diseases
Neuroactive ligand-receptor interaction
158 genes, 364 drugs (DrugBank) and 173 diseases
NOD-like receptor signaling pathway
32 genes, 51 drugs (DrugBank) and 74 diseases
Parathyroid hormone synthesis, secretion and action
22 genes, 58 drugs (DrugBank) and 72 diseases
Pathways in cancer
111 genes, 222 drugs (DrugBank) and 146 diseases
PI3K-Akt signaling pathway
85 genes, 142 drugs (DrugBank) and 131 diseases
Rap1 signaling pathway
45 genes, 113 drugs (DrugBank) and 98 diseases
Ras signaling pathway
37 genes, 64 drugs (DrugBank) and 70 diseases
Regulation of actin cytoskeleton
35 genes, 82 drugs (DrugBank) and 81 diseases
Tuberculosis
66 genes, 73 drugs (DrugBank) and 98 diseases