Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 6 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 7 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 8 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 9 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 10 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 11 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 12 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 13 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 14 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 15 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 16 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 17 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 18 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 19 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
ADRA1A 1件: ADRA1A 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 20 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
| 21 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 22 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 23 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 24 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 25 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 26 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 27 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 28 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 29 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 30 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 31 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 32 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 33 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 34 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 35 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 36 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 37 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 38 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 39 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
| 40 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 41 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 42 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 43 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 44 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 45 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 46 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 47 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 48 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 49 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 50 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 51 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 52 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 53 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 54 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 55 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 56 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 57 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 58 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 59 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 60 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 61 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 62 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 63 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 64 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 65 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 66 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 67 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 68 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 69 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 70 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 71 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 72 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 73 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 74 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 75 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 76 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 77 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 78 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 79 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 80 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 81 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 1件: SERPINC1 💬
|
Adomiparin Adomiparin 💬
| Heparin | 047 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬
|
| 82 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 83 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 84 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 85 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 86 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 87 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 88 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 89 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 90 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 91 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 92 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 93 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 94 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 95 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 96 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 97 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 98 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 99 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 100 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 101 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 102 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 103 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 1件: OPRM1 💬
|
Sufentanil Sufentanil 💬
| Sufentanil | 070 2件: 70, 280 💬
|
| 104 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 105 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 106 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 107 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 108 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 109 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 110 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 111 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 112 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 113 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 114 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 115 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 116 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 117 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 118 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 119 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 120 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 121 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 122 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 123 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 124 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 125 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 126 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 127 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 128 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 129 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 130 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 131 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 132 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 133 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 134 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 135 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 136 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 137 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 138 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 139 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 140 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 141 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 142 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 143 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 144 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 145 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 146 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 147 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 148 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 149 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 150 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 151 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 152 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 153 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 154 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 155 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 156 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 157 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 158 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 159 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 160 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 161 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 162 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 163 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 164 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 165 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 166 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 167 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 168 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 169 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 170 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 171 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 172 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 173 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 174 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 175 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 176 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 177 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 178 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 179 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 180 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 181 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 182 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 183 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 184 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 185 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 186 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 187 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 188 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 189 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 190 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 191 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 192 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 193 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 194 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 195 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 196 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 197 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 198 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 199 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 200 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
| 201 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 202 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 203 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 204 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 205 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 1件: OPRM1 💬
|
Sufentanil Sufentanil 💬
| Sufentanil | 070 2件: 70, 280 💬
|
| 206 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 207 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 208 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 209 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 210 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 211 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 212 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 213 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 214 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 215 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬
|
Dexmedetomidine Dexmedetomidine 💬
| Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
|
| 216 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRM1 1件: OPRM1 💬
|
Sufentanil Sufentanil 💬
| Sufentanil | 070 2件: 70, 280 💬
|
| 217 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 218 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 219 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 220 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 221 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 222 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 223 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 224 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 225 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 226 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 227 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 228 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 229 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 230 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 231 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 232 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 233 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 234 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 235 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 236 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 237 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 238 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 239 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 240 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 241 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 242 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 243 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 244 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 245 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 246 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 247 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 248 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 249 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 250 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 251 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 252 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 253 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 254 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 255 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 256 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 257 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 258 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 259 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 260 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 261 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 262 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 263 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 264 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 265 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 266 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 267 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 268 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 269 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 270 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 271 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 272 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 273 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 274 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 275 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 276 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 277 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 278 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 279 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 280 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 281 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 282 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 283 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 284 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 285 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 286 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 287 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 288 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 289 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 290 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 291 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 292 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 293 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 294 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 295 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 296 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 297 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 298 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 299 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 300 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 301 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 302 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 303 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 304 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 305 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 306 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 307 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 308 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬
|
Lovastatin Lovastatin 💬
| Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
|
| 309 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 310 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 311 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 312 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 313 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 314 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 315 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 316 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 317 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 318 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 319 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 320 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 321 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 322 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 323 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 324 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 325 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 326 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 327 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 328 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬
|
Methylergometrine Methylergometrine 💬
| Methylergometrine | 280 1件: 280 💬
|
| 329 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 330 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 331 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 332 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 333 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 334 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
| 335 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 336 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 337 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|