Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Adipocytokine signaling pathway 💬 18 genes, 40 drugs (DrugBank) and 108 diseases |
JAK2 1件: JAK2 💬Adipocytokine signaling pathway
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Baricitinib Baricitinib 💬Adipocytokine signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬1. Adipocytokine signaling pathway
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| 2 | AGE-RAGE signaling pathway in diabetic complications 💬 28 genes, 58 drugs (DrugBank) and 100 diseases |
JAK2 1件: JAK2 💬AGE-RAGE signaling pathway in diabetic complications
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Baricitinib Baricitinib 💬AGE-RAGE signaling pathway in diabetic complications
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬2. AGE-RAGE signaling pathway in diabetic complications
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| 3 | Chemical carcinogenesis - receptor activation 💬 41 genes, 140 drugs (DrugBank) and 133 diseases |
JAK2 1件: JAK2 💬Chemical carcinogenesis - receptor activation
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Baricitinib Baricitinib 💬Chemical carcinogenesis - receptor activation
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬3. Chemical carcinogenesis - receptor activation
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| 4 | Chemokine signaling pathway 💬 25 genes, 38 drugs (DrugBank) and 66 diseases |
JAK2 1件: JAK2 💬Chemokine signaling pathway
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Baricitinib Baricitinib 💬Chemokine signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬4. Chemokine signaling pathway
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| 5 | Cholinergic synapse 💬 32 genes, 65 drugs (DrugBank) and 87 diseases |
JAK2 1件: JAK2 💬Cholinergic synapse
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Baricitinib Baricitinib 💬Cholinergic synapse
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬5. Cholinergic synapse
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| 6 | Coronavirus disease 💬 56 genes, 115 drugs (DrugBank) and 109 diseases |
JAK1 1件: JAK1 💬Coronavirus disease
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Baricitinib Baricitinib 💬Coronavirus disease
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬6. Coronavirus disease
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| 7 | Efferocytosis 💬 30 genes, 78 drugs (DrugBank) and 97 diseases |
JAK2 1件: JAK2 💬Efferocytosis
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Baricitinib Baricitinib 💬Efferocytosis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬7. Efferocytosis
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| 8 | Epstein-Barr virus infection 💬 67 genes, 97 drugs (DrugBank) and 83 diseases |
JAK1 1件: JAK1 💬Epstein-Barr virus infection
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Baricitinib Baricitinib 💬Epstein-Barr virus infection
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬8. Epstein-Barr virus infection
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| 9 | Growth hormone synthesis, secretion and action 💬 23 genes, 49 drugs (DrugBank) and 97 diseases |
JAK2 1件: JAK2 💬Growth hormone synthesis, secretion and action
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Baricitinib Baricitinib 💬Growth hormone synthesis, secretion and action
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬9. Growth hormone synthesis, secretion and action
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| 10 | Hepatitis B 💬 44 genes, 70 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Hepatitis B
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬10. Hepatitis B
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| 11 | Hepatitis C 💬 37 genes, 75 drugs (DrugBank) and 92 diseases |
JAK1 1件: JAK1 💬Hepatitis C
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Baricitinib Baricitinib 💬Hepatitis C
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬11. Hepatitis C
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| 12 | Herpes simplex virus 1 infection 💬 71 genes, 85 drugs (DrugBank) and 110 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Herpes simplex virus 1 infection
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬12. Herpes simplex virus 1 infection
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| 13 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
JAK2 1件: JAK2 💬Hormone signaling
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Baricitinib Baricitinib 💬Hormone signaling
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬13. Hormone signaling
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| 14 | Human cytomegalovirus infection 💬 65 genes, 121 drugs (DrugBank) and 136 diseases |
JAK1 1件: JAK1 💬Human cytomegalovirus infection
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Baricitinib Baricitinib 💬Human cytomegalovirus infection
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬14. Human cytomegalovirus infection
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| 15 | Human papillomavirus infection 💬 52 genes, 114 drugs (DrugBank) and 121 diseases |
JAK1 1件: JAK1 💬Human papillomavirus infection
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Baricitinib Baricitinib 💬Human papillomavirus infection
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬15. Human papillomavirus infection
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| 16 | Human T-cell leukemia virus 1 infection 💬 61 genes, 80 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬Human T-cell leukemia virus 1 infection
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Baricitinib Baricitinib 💬Human T-cell leukemia virus 1 infection
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬16. Human T-cell leukemia virus 1 infection
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| 17 | Influenza A 💬 67 genes, 84 drugs (DrugBank) and 101 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Influenza A
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬17. Influenza A
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| 18 | JAK-STAT signaling pathway 💬 60 genes, 117 drugs (DrugBank) and 116 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬JAK-STAT signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬18. JAK-STAT signaling pathway
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| 19 | Kaposi sarcoma-associated herpesvirus infection 💬 61 genes, 102 drugs (DrugBank) and 124 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Kaposi sarcoma-associated herpesvirus infection
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬19. Kaposi sarcoma-associated herpesvirus infection
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| 20 | Leishmaniasis 💬 40 genes, 76 drugs (DrugBank) and 105 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Leishmaniasis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬20. Leishmaniasis
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| 21 | Lipid and atherosclerosis 💬 52 genes, 73 drugs (DrugBank) and 107 diseases |
JAK2 1件: JAK2 💬Lipid and atherosclerosis
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Baricitinib Baricitinib 💬Lipid and atherosclerosis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬21. Lipid and atherosclerosis
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| 22 | Measles 💬 42 genes, 72 drugs (DrugBank) and 70 diseases |
JAK1 1件: JAK1 💬Measles
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Baricitinib Baricitinib 💬Measles
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬22. Measles
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| 23 | Necroptosis 💬 34 genes, 60 drugs (DrugBank) and 82 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Necroptosis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬23. Necroptosis
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| 24 | NOD-like receptor signaling pathway 💬 33 genes, 57 drugs (DrugBank) and 79 diseases |
JAK1 1件: JAK1 💬NOD-like receptor signaling pathway
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Baricitinib Baricitinib 💬NOD-like receptor signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬24. NOD-like receptor signaling pathway
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| 25 | Osteoclast differentiation 💬 40 genes, 93 drugs (DrugBank) and 109 diseases |
JAK1 1件: JAK1 💬Osteoclast differentiation
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Baricitinib Baricitinib 💬Osteoclast differentiation
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬25. Osteoclast differentiation
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| 26 | Pancreatic cancer 💬 20 genes, 43 drugs (DrugBank) and 86 diseases |
JAK1 1件: JAK1 💬Pancreatic cancer
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Baricitinib Baricitinib 💬Pancreatic cancer
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬26. Pancreatic cancer
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| 27 | Pathways in cancer 💬 116 genes, 235 drugs (DrugBank) and 150 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Pathways in cancer
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬27. Pathways in cancer
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| 28 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 70 drugs (DrugBank) and 104 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬PD-L1 expression and PD-1 checkpoint pathway in cancer
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬28. PD-L1 expression and PD-1 checkpoint pathway in cancer
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| 29 | PI3K-Akt signaling pathway 💬 86 genes, 147 drugs (DrugBank) and 129 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬PI3K-Akt signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬29. PI3K-Akt signaling pathway
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| 30 | Prolactin signaling pathway 💬 20 genes, 44 drugs (DrugBank) and 74 diseases |
JAK2 1件: JAK2 💬Prolactin signaling pathway
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Baricitinib Baricitinib 💬Prolactin signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬30. Prolactin signaling pathway
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| 31 | Signaling pathways regulating pluripotency of stem cells 💬 21 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Signaling pathways regulating pluripotency of stem cells
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬31. Signaling pathways regulating pluripotency of stem cells
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| 32 | Th1 and Th2 cell differentiation 💬 45 genes, 57 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Th1 and Th2 cell differentiation
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬32. Th1 and Th2 cell differentiation
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| 33 | Th17 cell differentiation 💬 57 genes, 88 drugs (DrugBank) and 111 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Th17 cell differentiation
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬33. Th17 cell differentiation
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| 34 | Toll-like receptor signaling pathway 💬 41 genes, 68 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬Toll-like receptor signaling pathway
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Baricitinib Baricitinib 💬Toll-like receptor signaling pathway
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬34. Toll-like receptor signaling pathway
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| 35 | Toxoplasmosis 💬 41 genes, 53 drugs (DrugBank) and 78 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Toxoplasmosis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬35. Toxoplasmosis
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| 36 | Tuberculosis 💬 67 genes, 80 drugs (DrugBank) and 104 diseases |
JAK1 2件: JAK1, JAK2 💬
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Baricitinib Baricitinib 💬Tuberculosis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬36. Tuberculosis
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| 37 | Viral carcinogenesis 💬 32 genes, 34 drugs (DrugBank) and 60 diseases |
JAK1 1件: JAK1 💬Viral carcinogenesis
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Baricitinib Baricitinib 💬Viral carcinogenesis
| Baricitinib | 002 24件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬37. Viral carcinogenesis
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Adipocytokine signaling pathway
18 genes, 40 drugs (DrugBank) and 108 diseases
AGE-RAGE signaling pathway in diabetic complications
28 genes, 58 drugs (DrugBank) and 100 diseases
Chemical carcinogenesis - receptor activation
41 genes, 140 drugs (DrugBank) and 133 diseases
Chemokine signaling pathway
25 genes, 38 drugs (DrugBank) and 66 diseases
Cholinergic synapse
32 genes, 65 drugs (DrugBank) and 87 diseases
Coronavirus disease
56 genes, 115 drugs (DrugBank) and 109 diseases
Efferocytosis
30 genes, 78 drugs (DrugBank) and 97 diseases
Epstein-Barr virus infection
67 genes, 97 drugs (DrugBank) and 83 diseases
Growth hormone synthesis, secretion and action
23 genes, 49 drugs (DrugBank) and 97 diseases
Hepatitis B
44 genes, 70 drugs (DrugBank) and 92 diseases
Hepatitis C
37 genes, 75 drugs (DrugBank) and 92 diseases
Herpes simplex virus 1 infection
71 genes, 85 drugs (DrugBank) and 110 diseases
Hormone signaling
64 genes, 217 drugs (DrugBank) and 150 diseases
Human cytomegalovirus infection
65 genes, 121 drugs (DrugBank) and 136 diseases
Human papillomavirus infection
52 genes, 114 drugs (DrugBank) and 121 diseases
Human T-cell leukemia virus 1 infection
61 genes, 80 drugs (DrugBank) and 105 diseases
Influenza A
67 genes, 84 drugs (DrugBank) and 101 diseases
JAK-STAT signaling pathway
60 genes, 117 drugs (DrugBank) and 116 diseases
Kaposi sarcoma-associated herpesvirus infection
61 genes, 102 drugs (DrugBank) and 124 diseases
Leishmaniasis
40 genes, 76 drugs (DrugBank) and 105 diseases
Lipid and atherosclerosis
52 genes, 73 drugs (DrugBank) and 107 diseases
Measles
42 genes, 72 drugs (DrugBank) and 70 diseases
Necroptosis
34 genes, 60 drugs (DrugBank) and 82 diseases
NOD-like receptor signaling pathway
33 genes, 57 drugs (DrugBank) and 79 diseases
Osteoclast differentiation
40 genes, 93 drugs (DrugBank) and 109 diseases
Pancreatic cancer
20 genes, 43 drugs (DrugBank) and 86 diseases
Pathways in cancer
116 genes, 235 drugs (DrugBank) and 150 diseases
PD-L1 expression and PD-1 checkpoint pathway in cancer
34 genes, 70 drugs (DrugBank) and 104 diseases
PI3K-Akt signaling pathway
86 genes, 147 drugs (DrugBank) and 129 diseases
Prolactin signaling pathway
20 genes, 44 drugs (DrugBank) and 74 diseases
Signaling pathways regulating pluripotency of stem cells
21 genes, 39 drugs (DrugBank) and 64 diseases
Th1 and Th2 cell differentiation
45 genes, 57 drugs (DrugBank) and 83 diseases
Th17 cell differentiation
57 genes, 88 drugs (DrugBank) and 111 diseases
Toll-like receptor signaling pathway
41 genes, 68 drugs (DrugBank) and 84 diseases
Toxoplasmosis
41 genes, 53 drugs (DrugBank) and 78 diseases
Tuberculosis
67 genes, 80 drugs (DrugBank) and 104 diseases
Viral carcinogenesis
32 genes, 34 drugs (DrugBank) and 60 diseases