Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | ||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABC transporters 💬 4 genes, 14 drugs (DrugBank) and 10 diseases |
CFTR 1件: CFTR 💬ABC transporters
|
Ivacaftor Ivacaftor 💬ABC transporters
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 2 | Adrenergic signaling in cardiomyocytes 💬 31 genes, 86 drugs (DrugBank) and 81 diseases |
ADRB2 1件: ADRB2 💬Adrenergic signaling in cardiomyocytes
|
Albuterol sulfate Albuterol sulfate 💬Adrenergic signaling in cardiomyocytes
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬2. Adrenergic signaling in cardiomyocytes
|
||||||||||||||||||||||||||||||||||||||
| 3 | Adrenergic signaling in cardiomyocytes 💬 31 genes, 86 drugs (DrugBank) and 81 diseases |
ADRB2 1件: ADRB2 💬Adrenergic signaling in cardiomyocytes
|
Albuterol Albuterol 💬Adrenergic signaling in cardiomyocytes
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬2. Adrenergic signaling in cardiomyocytes
|
||||||||||||||||||||||||||||||||||||||
| 4 | Alzheimer disease 💬 59 genes, 136 drugs (DrugBank) and 139 diseases |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Alzheimer disease
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 5 | AMPK signaling pathway 💬 16 genes, 58 drugs (DrugBank) and 100 diseases |
CFTR 1件: CFTR 💬AMPK signaling pathway
|
Ivacaftor Ivacaftor 💬AMPK signaling pathway
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 6 | Bile secretion 💬 13 genes, 36 drugs (DrugBank) and 66 diseases |
CFTR 1件: CFTR 💬Bile secretion
|
Ivacaftor Ivacaftor 💬Bile secretion
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 7 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
ADRB2 1件: ADRB2 💬Calcium signaling pathway
|
Albuterol sulfate Albuterol sulfate 💬Calcium signaling pathway
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬7. Calcium signaling pathway
|
||||||||||||||||||||||||||||||||||||||
| 8 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
ADRB2 1件: ADRB2 💬Calcium signaling pathway
|
Albuterol Albuterol 💬Calcium signaling pathway
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬7. Calcium signaling pathway
|
||||||||||||||||||||||||||||||||||||||
| 9 | Calcium signaling pathway 💬 82 genes, 215 drugs (DrugBank) and 140 diseases |
CHRM1 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Calcium signaling pathway
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 10 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
ADRB2 1件: ADRB2 💬cAMP signaling pathway
|
Albuterol sulfate Albuterol sulfate 💬cAMP signaling pathway
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬10. cAMP signaling pathway
|
||||||||||||||||||||||||||||||||||||||
| 11 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
ADRB2 1件: ADRB2 💬cAMP signaling pathway
|
Albuterol Albuterol 💬cAMP signaling pathway
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬10. cAMP signaling pathway
|
||||||||||||||||||||||||||||||||||||||
| 12 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
CFTR 1件: CFTR 💬cAMP signaling pathway
|
Ivacaftor Ivacaftor 💬cAMP signaling pathway
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 13 | cAMP signaling pathway 💬 67 genes, 191 drugs (DrugBank) and 133 diseases |
CHRM1 2件: CHRM1, CHRM2 💬
|
Methacholine chloride Methacholine chloride 💬cAMP signaling pathway
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 14 | cGMP-PKG signaling pathway 💬 48 genes, 132 drugs (DrugBank) and 123 diseases |
ADRB2 1件: ADRB2 💬cGMP-PKG signaling pathway
|
Albuterol sulfate Albuterol sulfate 💬cGMP-PKG signaling pathway
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬14. cGMP-PKG signaling pathway
|
||||||||||||||||||||||||||||||||||||||
| 15 | cGMP-PKG signaling pathway 💬 48 genes, 132 drugs (DrugBank) and 123 diseases |
ADRB2 1件: ADRB2 💬cGMP-PKG signaling pathway
|
Albuterol Albuterol 💬cGMP-PKG signaling pathway
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬14. cGMP-PKG signaling pathway
|
||||||||||||||||||||||||||||||||||||||
| 16 | Chemical carcinogenesis - receptor activation 💬 41 genes, 140 drugs (DrugBank) and 133 diseases |
ADRB2 1件: ADRB2 💬Chemical carcinogenesis - receptor activation
|
Albuterol sulfate Albuterol sulfate 💬Chemical carcinogenesis - receptor activation
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬16. Chemical carcinogenesis - receptor activation
|
||||||||||||||||||||||||||||||||||||||
| 17 | Chemical carcinogenesis - receptor activation 💬 41 genes, 140 drugs (DrugBank) and 133 diseases |
ADRB2 1件: ADRB2 💬Chemical carcinogenesis - receptor activation
|
Albuterol Albuterol 💬Chemical carcinogenesis - receptor activation
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬16. Chemical carcinogenesis - receptor activation
|
||||||||||||||||||||||||||||||||||||||
| 18 | Cholinergic synapse 💬 32 genes, 65 drugs (DrugBank) and 87 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Cholinergic synapse
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 19 | Gastric acid secretion 💬 14 genes, 54 drugs (DrugBank) and 63 diseases |
CFTR 1件: CFTR 💬Gastric acid secretion
|
Ivacaftor Ivacaftor 💬Gastric acid secretion
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 20 | Gastric acid secretion 💬 14 genes, 54 drugs (DrugBank) and 63 diseases |
CHRM3 1件: CHRM3 💬Gastric acid secretion
|
Methacholine chloride Methacholine chloride 💬Gastric acid secretion
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 21 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
ADRB2 1件: ADRB2 💬Hormone signaling
|
Albuterol sulfate Albuterol sulfate 💬Hormone signaling
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬21. Hormone signaling
|
||||||||||||||||||||||||||||||||||||||
| 22 | Hormone signaling 💬 64 genes, 217 drugs (DrugBank) and 150 diseases |
ADRB2 1件: ADRB2 💬Hormone signaling
|
Albuterol Albuterol 💬Hormone signaling
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬21. Hormone signaling
|
||||||||||||||||||||||||||||||||||||||
| 23 | Insulin secretion 💬 16 genes, 51 drugs (DrugBank) and 61 diseases |
CHRM3 1件: CHRM3 💬Insulin secretion
|
Methacholine chloride Methacholine chloride 💬Insulin secretion
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 24 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
ADRB2 1件: ADRB2 💬Neuroactive ligand signaling
|
Albuterol sulfate Albuterol sulfate 💬Neuroactive ligand signaling
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬24. Neuroactive ligand signaling
|
||||||||||||||||||||||||||||||||||||||
| 25 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
ADRB2 1件: ADRB2 💬Neuroactive ligand signaling
|
Albuterol Albuterol 💬Neuroactive ligand signaling
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬24. Neuroactive ligand signaling
|
||||||||||||||||||||||||||||||||||||||
| 26 | Neuroactive ligand signaling 💬 92 genes, 239 drugs (DrugBank) and 118 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Neuroactive ligand signaling
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 27 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
ADRB2 1件: ADRB2 💬Neuroactive ligand-receptor interaction
|
Albuterol sulfate Albuterol sulfate 💬Neuroactive ligand-receptor interaction
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬27. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||
| 28 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
ADRB2 1件: ADRB2 💬Neuroactive ligand-receptor interaction
|
Albuterol Albuterol 💬Neuroactive ligand-receptor interaction
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬27. Neuroactive ligand-receptor interaction
|
||||||||||||||||||||||||||||||||||||||
| 29 | Neuroactive ligand-receptor interaction 💬 156 genes, 371 drugs (DrugBank) and 171 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Neuroactive ligand-receptor interaction
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 30 | Pancreatic secretion 💬 18 genes, 46 drugs (DrugBank) and 56 diseases |
CFTR 1件: CFTR 💬Pancreatic secretion
|
Ivacaftor Ivacaftor 💬Pancreatic secretion
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 31 | Pancreatic secretion 💬 18 genes, 46 drugs (DrugBank) and 56 diseases |
CHRM3 1件: CHRM3 💬Pancreatic secretion
|
Methacholine chloride Methacholine chloride 💬Pancreatic secretion
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 32 | Pathways of neurodegeneration - multiple diseases 💬 64 genes, 143 drugs (DrugBank) and 141 diseases |
CHRM1 3件: CHRM1, CHRM3, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Pathways of neurodegeneration - multiple diseases
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 33 | Phagocytosis 💬 44 genes, 34 drugs (DrugBank) and 43 diseases |
CFTR 1件: CFTR 💬Phagocytosis
|
Ivacaftor Ivacaftor 💬Phagocytosis
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 34 | PI3K-Akt signaling pathway 💬 86 genes, 147 drugs (DrugBank) and 129 diseases |
CHRM1 2件: CHRM1, CHRM2 💬
|
Methacholine chloride Methacholine chloride 💬PI3K-Akt signaling pathway
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 35 | Regulation of actin cytoskeleton 💬 37 genes, 82 drugs (DrugBank) and 79 diseases |
CHRM1 5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬
|
Methacholine chloride Methacholine chloride 💬Regulation of actin cytoskeleton
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 36 | Regulation of lipolysis in adipocytes 💬 13 genes, 72 drugs (DrugBank) and 80 diseases |
ADRB2 1件: ADRB2 💬Regulation of lipolysis in adipocytes
|
Albuterol sulfate Albuterol sulfate 💬Regulation of lipolysis in adipocytes
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬36. Regulation of lipolysis in adipocytes
|
||||||||||||||||||||||||||||||||||||||
| 37 | Regulation of lipolysis in adipocytes 💬 13 genes, 72 drugs (DrugBank) and 80 diseases |
ADRB2 1件: ADRB2 💬Regulation of lipolysis in adipocytes
|
Albuterol Albuterol 💬Regulation of lipolysis in adipocytes
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬36. Regulation of lipolysis in adipocytes
|
||||||||||||||||||||||||||||||||||||||
| 38 | Renin secretion 💬 28 genes, 90 drugs (DrugBank) and 108 diseases |
ADRB2 1件: ADRB2 💬Renin secretion
|
Albuterol sulfate Albuterol sulfate 💬Renin secretion
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬38. Renin secretion
|
||||||||||||||||||||||||||||||||||||||
| 39 | Renin secretion 💬 28 genes, 90 drugs (DrugBank) and 108 diseases |
ADRB2 1件: ADRB2 💬Renin secretion
|
Albuterol Albuterol 💬Renin secretion
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬38. Renin secretion
|
||||||||||||||||||||||||||||||||||||||
| 40 | Salivary secretion 💬 20 genes, 75 drugs (DrugBank) and 75 diseases |
ADRB2 1件: ADRB2 💬Salivary secretion
|
Albuterol sulfate Albuterol sulfate 💬Salivary secretion
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬40. Salivary secretion
|
||||||||||||||||||||||||||||||||||||||
| 41 | Salivary secretion 💬 20 genes, 75 drugs (DrugBank) and 75 diseases |
ADRB2 1件: ADRB2 💬Salivary secretion
|
Albuterol Albuterol 💬Salivary secretion
| Albuterol | 012 9件: 12, 13, 86, 89, 113, 231, 256, 299, 340 💬40. Salivary secretion
|
||||||||||||||||||||||||||||||||||||||
| 42 | Salivary secretion 💬 20 genes, 75 drugs (DrugBank) and 75 diseases |
CHRM3 1件: CHRM3 💬Salivary secretion
|
Methacholine chloride Methacholine chloride 💬Salivary secretion
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 43 | Taste transduction 💬 29 genes, 93 drugs (DrugBank) and 78 diseases |
CHRM3 1件: CHRM3 💬Taste transduction
|
Methacholine chloride Methacholine chloride 💬Taste transduction
| Methacholine | 096 2件: 96, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 44 | Tight junction 💬 13 genes, 38 drugs (DrugBank) and 54 diseases |
CFTR 1件: CFTR 💬Tight junction
|
Ivacaftor Ivacaftor 💬Tight junction
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
||||||||||||||||||||||||||||||||||||||
| 45 | Vibrio cholerae infection 💬 3 genes, 14 drugs (DrugBank) and 15 diseases |
CFTR 1件: CFTR 💬Vibrio cholerae infection
|
Ivacaftor Ivacaftor 💬Vibrio cholerae infection
| Ivacaftor | 298 3件: 298, 299, 340 💬
|
ABC transporters
4 genes, 14 drugs (DrugBank) and 10 diseases
Adrenergic signaling in cardiomyocytes
31 genes, 86 drugs (DrugBank) and 81 diseases
Alzheimer disease
59 genes, 136 drugs (DrugBank) and 139 diseases
AMPK signaling pathway
16 genes, 58 drugs (DrugBank) and 100 diseases
Bile secretion
13 genes, 36 drugs (DrugBank) and 66 diseases
Calcium signaling pathway
82 genes, 215 drugs (DrugBank) and 140 diseases
cAMP signaling pathway
67 genes, 191 drugs (DrugBank) and 133 diseases
cGMP-PKG signaling pathway
48 genes, 132 drugs (DrugBank) and 123 diseases
Chemical carcinogenesis - receptor activation
41 genes, 140 drugs (DrugBank) and 133 diseases
Cholinergic synapse
32 genes, 65 drugs (DrugBank) and 87 diseases
Gastric acid secretion
14 genes, 54 drugs (DrugBank) and 63 diseases
Hormone signaling
64 genes, 217 drugs (DrugBank) and 150 diseases
Insulin secretion
16 genes, 51 drugs (DrugBank) and 61 diseases
Neuroactive ligand signaling
92 genes, 239 drugs (DrugBank) and 118 diseases
Neuroactive ligand-receptor interaction
156 genes, 371 drugs (DrugBank) and 171 diseases
Pancreatic secretion
18 genes, 46 drugs (DrugBank) and 56 diseases
Pathways of neurodegeneration - multiple diseases
64 genes, 143 drugs (DrugBank) and 141 diseases
Phagocytosis
44 genes, 34 drugs (DrugBank) and 43 diseases
PI3K-Akt signaling pathway
86 genes, 147 drugs (DrugBank) and 129 diseases
Regulation of actin cytoskeleton
37 genes, 82 drugs (DrugBank) and 79 diseases
Regulation of lipolysis in adipocytes
13 genes, 72 drugs (DrugBank) and 80 diseases
Renin secretion
28 genes, 90 drugs (DrugBank) and 108 diseases
Salivary secretion
20 genes, 75 drugs (DrugBank) and 75 diseases
Taste transduction
29 genes, 93 drugs (DrugBank) and 78 diseases
Tight junction
13 genes, 38 drugs (DrugBank) and 54 diseases
Vibrio cholerae infection
3 genes, 14 drugs (DrugBank) and 15 diseases