Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
4 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
5 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
6 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
7 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
8 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
9 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
10 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
11 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
12 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
13 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
14 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
15 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
16 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
17 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
18 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
19 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
20 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
21 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
22 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
23 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
24 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
25 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
26 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
27 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
28 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
29 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
30 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
31 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
32 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
33 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
34 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
35 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
36 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
37 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
38 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
39 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
40 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
41 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
42 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
43 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
44 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
45 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
46 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
47 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
48 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
49 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
50 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
51 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
52 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
53 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
54 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
55 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
56 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
57 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
58 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
59 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
60 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
61 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
62 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
63 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
64 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
65 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
66 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
67 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
PDCD1 1件: PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
68 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
69 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
70 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
71 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
72 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 1件: OPRD1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
73 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
74 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
75 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
76 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
77 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
78 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
79 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
80 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
81 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
82 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
83 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
84 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
85 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
86 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
87 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
88 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
89 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
90 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
91 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
92 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF2RA 1件: CSF2RA 💬
|
Mavrilimumab Mavrilimumab 💬
| Mavrilimumab | 041 2件: 41, 46 💬
|
93 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R 1件: CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
94 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
95 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
96 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
97 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
98 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
99 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
100 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
101 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
102 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
103 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
104 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
105 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
106 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
107 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
108 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
109 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
110 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
111 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
112 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
113 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
114 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
115 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
116 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
117 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
118 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
119 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
120 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 1件: OPRM1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
121 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
122 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
123 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
124 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
125 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
126 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
127 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
128 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
129 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
130 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
131 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
132 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
133 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
134 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
135 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
136 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
137 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF2RA 1件: CSF2RA 💬
|
Mavrilimumab Mavrilimumab 💬
| Mavrilimumab | 041 2件: 41, 46 💬
|
138 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R 1件: CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
139 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
140 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
141 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
142 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
143 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
144 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 1件: MS4A1 💬
|
Rituximab Rituximab 💬
| Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
|
145 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
146 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
147 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
148 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
149 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
150 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
151 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
152 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
153 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
154 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
155 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
156 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
157 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
158 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
159 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
160 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
161 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
162 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
163 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
164 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
165 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
166 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
167 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
168 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
169 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
170 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
171 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
172 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
173 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
174 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
175 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
176 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
177 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
178 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
179 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
180 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
181 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
182 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
183 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
184 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 2件: IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
185 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
186 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
187 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
188 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
189 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
190 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
191 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
192 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
193 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
194 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
195 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
196 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
197 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
198 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
199 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
200 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
201 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
202 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
203 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
204 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
205 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
206 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
207 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
208 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
209 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
210 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
211 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
212 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
213 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
214 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
215 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
216 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
217 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
218 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
219 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
220 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
221 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF2RA 1件: CSF2RA 💬
|
Mavrilimumab Mavrilimumab 💬
| Mavrilimumab | 041 2件: 41, 46 💬
|
222 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R 1件: CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
223 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
224 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
225 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
226 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
227 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
228 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
229 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
230 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
CD86 1件: CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
231 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
232 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
233 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
234 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
235 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
236 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
237 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
238 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
239 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
240 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
241 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
242 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
243 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
244 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
245 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
246 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
247 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
248 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
249 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
250 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
251 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
252 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
253 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
254 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A 1件: IL12A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
255 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
256 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
257 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
258 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
259 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
260 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
261 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
262 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
263 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
264 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
265 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
266 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
267 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
268 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
269 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
270 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
271 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
272 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
273 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
274 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 1件: OPRM1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
275 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
276 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
277 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
278 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
279 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
280 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
281 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
282 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
283 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
284 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
285 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
286 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
287 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Hydrocortisone Hydrocortisone 💬
| Hydrocortisone | 006 10件: 6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
|
288 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Methylprednisolone Methylprednisolone 💬
| Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
|
289 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Prednisolone Prednisolone 💬
| Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
|
290 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Prednisone Prednisone 💬
| Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
|
291 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬
|
Prednisone acetate Prednisone acetate 💬
| Prednisone acetate | 035 6件: 35, 41, 46, 49, 162, 224 💬
|
292 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 3件: OPRD1, OPRK1, OPRM1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
293 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
294 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
295 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
296 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
297 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
298 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
299 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
300 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
301 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
302 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
303 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
304 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
305 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
306 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
307 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
308 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
309 | One carbon pool by folate 💬 3 genes, 2 drugs (DrugBank) and 38 diseases |
DHFR 2件: DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
310 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
311 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
312 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
313 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
314 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
315 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
316 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
317 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
318 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
319 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
320 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
321 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
322 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
323 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
324 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
325 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
326 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
327 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF2RA 1件: CSF2RA 💬
|
Mavrilimumab Mavrilimumab 💬
| Mavrilimumab | 041 2件: 41, 46 💬
|
328 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R 1件: CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
329 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
330 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA 2件: EDNRA, EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
331 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
332 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
333 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
334 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
335 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
336 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
337 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
338 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
339 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
340 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
341 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
342 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
343 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
344 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
345 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PDCD1 1件: PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
346 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
347 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
348 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
349 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
350 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
351 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
352 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
353 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R 1件: CSF3R 💬
|
Filgrastim Filgrastim 💬
| Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
|
354 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
355 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
356 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
357 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
358 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
359 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
360 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
361 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
362 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
363 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
364 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 1件: JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
365 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 1件: IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
366 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B 1件: IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
367 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
368 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
369 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
370 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
371 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
372 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
373 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
374 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
375 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
376 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
377 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
378 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A 1件: IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
379 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
380 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
381 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
382 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
383 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
384 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
385 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
386 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
387 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
388 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
389 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
390 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
391 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
392 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
393 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
394 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
395 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 1件: OPRD1 💬
|
Naltrexone Naltrexone 💬
| Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
|
396 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
397 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
398 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
399 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
400 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
401 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PDCD1 1件: PDCD1 💬
|
Nivolumab Nivolumab 💬
| Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
|
402 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
403 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
404 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
405 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
FDPS 1件: FDPS 💬
|
Alendronic acid Alendronic acid 💬
| Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬
|
406 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
407 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
408 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
409 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
410 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
411 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
412 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
413 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
414 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
415 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
416 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
417 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
418 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
419 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
420 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
421 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
422 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
423 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
424 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
425 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
426 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
427 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
428 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
429 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
430 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
431 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
432 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
433 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
434 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
435 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
436 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
437 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
438 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
CD86 1件: CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
439 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 1件: IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
440 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
441 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
442 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
443 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
444 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
445 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
446 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
447 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
448 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
449 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
450 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR 1件: VDR 💬
|
Alfacalcidol Alfacalcidol 💬
| Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬
|
451 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
452 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL12A 2件: IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
453 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
454 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
455 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
456 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
457 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
458 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
459 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA 1件: EDNRA 💬
|
Bosentan Bosentan 💬
| Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
|
460 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
461 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 1件: JAK1 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
462 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
463 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
464 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
465 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
466 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
467 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
468 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
469 | Virion - Adenovirus 💬 2 genes, 2 drugs (DrugBank) and 26 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
470 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
471 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
472 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
473 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
474 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|