Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Angiotensin II Angiotensin II 💬
| Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬
|
2 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Angiotensin II Angiotensin II 💬
| Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬
|
3 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Candesartan Candesartan 💬
| Candesartan | 058 2件: 58, 67 💬
|
4 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Candesartan cilexetil Candesartan cilexetil 💬
| Candesartan cilexetil | 067 1件: 67 💬
|
5 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Irbesartan Irbesartan 💬
| Irbesartan | 066 4件: 66, 167, 168, 222 💬
|
6 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
7 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Sparsentan Sparsentan 💬
| Sparsentan | 066 3件: 66, 218, 222 💬
|
8 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Telmisartan Telmisartan 💬
| Telmisartan | 066 2件: 66, 67 💬
|
9 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 1件: AGTR1 💬
|
Valsartan Valsartan 💬
| Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬
|
10 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digitoxin Digitoxin 💬
| Digitoxin | 299 1件: 299 💬
|
11 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
ATP1A1 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬
|
Digoxin Digoxin 💬
| Digoxin | 008 3件: 8 , 46, 210 💬
|
12 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Amlodipine Amlodipine 💬
| Amlodipine | 013 4件: 13, 51, 67, 298 💬
|
13 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Cilnidipine Cilnidipine 💬
| Cilnidipine | 067 1件: 67 💬
|
14 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Diltiazem Diltiazem 💬
| Diltiazem | 051 3件: 51, 58, 86 💬
|
15 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Isradipine Isradipine 💬
| Isradipine | 006 1件: 6 💬
|
16 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nicardipine Nicardipine 💬
| Nicardipine | 070 2件: 70, 86 💬
|
17 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nifedipine Nifedipine 💬
| Nifedipine | 050 2件: 50, 81 💬
|
18 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Nilvadipine Nilvadipine 💬
| Nilvadipine | 090 1件: 90 💬
|
19 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Perhexiline Perhexiline 💬
| Perhexiline | 058 2件: 58, 272 💬
|
20 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Propiverine Propiverine 💬
| Propiverine | 226 1件: 226 💬
|
21 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Topiramate Topiramate 💬
| Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬
|
22 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬
|
Verapamil Verapamil 💬
| Verapamil | 058 4件: 58, 96, 140, 167 💬
|
23 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Flunarizine Flunarizine 💬
| Flunarizine | 149 1件: 149 💬
|
24 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
25 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Zonisamide Zonisamide 💬
| Zonisamide | 006 1件: 6 💬
|
26 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CYP11A1 1件: CYP11A1 💬
|
Levoketoconazole Levoketoconazole 💬
| Levoketoconazole | 075 1件: 75 💬
|
27 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CYP11B2 1件: CYP11B2 💬
|
Osilodrostat Osilodrostat 💬
| Osilodrostat | 075 1件: 75 💬
|
28 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
KCNJ5 1件: KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
29 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
MC2R 1件: MC2R 💬
|
Corticotropin Corticotropin 💬
| Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
|
30 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
MC2R 1件: MC2R 💬
|
Cosyntropin Cosyntropin 💬
| Tetracosactide | 078 5件: 78, 83, 113, 145, 222 💬
|
31 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
NPR1 1件: NPR1 💬
|
Erythrityl tetranitrate Erythrityl tetranitrate 💬
| Erythrityl tetranitrate | 046 1件: 46 💬
|
32 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
NPR1 1件: NPR1 💬
|
Nesiritide Nesiritide 💬
| Nesiritide | 046 2件: 46, 58 💬
|
33 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 1件: 63 💬
|
34 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 1件: 246 💬
|
35 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
36 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
37 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Flavoxate Flavoxate 💬
| Flavoxate | 226 1件: 226 💬
|
38 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 2件: 236, 299 💬
|
39 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 2件: 236, 299 💬
|
40 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PRKCB 1件: PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 1件: 168 💬
|
41 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PRKCE 1件: PRKCE 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 1件: 97 💬
|