Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Allograft rejection 💬
1件: CD28 💬 Acazicolcept 💬 Acazicolcept 1件: 49 💬
2 Allograft rejection 💬
2件: CD80, CD86 💬 Abatacept 💬 Abatacept 27件:  2 , 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
3 Allograft rejection 💬
2件: CD80, CD86 💬 Belatacept 💬 Belatacept 1件: 46 💬
4 Allograft rejection 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
5 Allograft rejection 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
6 Allograft rejection 💬
2件: IL10, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
7 Allograft rejection 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
8 Allograft rejection 💬
1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
9 Allograft rejection 💬
1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
10 Allograft rejection 💬
1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
11 Allograft rejection 💬
20件: MHC1, MHC1, MHC1, MHC1, MHC1, MHC1, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
12 Allograft rejection 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
13 Allograft rejection 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
14 Allograft rejection 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
15 Allograft rejection 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
16 Allograft rejection 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
17 Allograft rejection 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
18 Allograft rejection 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
19 Allograft rejection 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
20 Allograft rejection 💬
1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
21 Allograft rejection 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
22 Allograft rejection 💬
1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
23 Allograft rejection 💬
1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
24 Allograft rejection 💬
1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
25 Allograft rejection 💬
1件: TNFSF5 💬 Frexalimab 💬 Frexalimab 2件: 13, 222 💬
26 Allograft rejection 💬
1件: TNFSF5 💬 Toralizumab 💬 Toralizumab 1件: 63 💬