Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Apelin signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
2 Apelin signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
3 Apelin signaling pathway 💬
 1件: AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
4 Apelin signaling pathway 💬
 1件: AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil 1件: 66 💬
5 Apelin signaling pathway 💬
 1件: AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil 1件: 66 💬
6 Apelin signaling pathway 💬
 1件: AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil 1件: 66 💬
7 Apelin signaling pathway 💬
 1件: AGTR1 💬 Buloxibutid 💬 Buloxibutid 1件: 85 💬
8 Apelin signaling pathway 💬
 1件: AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid 1件: 85 💬
9 Apelin signaling pathway 💬
 1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
10 Apelin signaling pathway 💬
 1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
11 Apelin signaling pathway 💬
 1件: AGTR1 💬 Losartan potassium 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
12 Apelin signaling pathway 💬
 1件: AGTR1 💬 Losartan 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13 Apelin signaling pathway 💬
 1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
14 Apelin signaling pathway 💬
 1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
15 Apelin signaling pathway 💬
 1件: AGTR1 💬 Valsartan 💬 Valsartan 8件: 57, 58, 66, 75, 86, 210, 222, 224 💬
16 Apelin signaling pathway 💬
 1件: CTGF 💬 Pamrevlumab 💬 Pamrevlumab 2件: 85, 113 💬
17 Apelin signaling pathway 💬
 2件: HDAC4_5, HDAC4_5 💬 Givinostat 💬 Givinostat 2件: 107, 113 💬
18 Apelin signaling pathway 💬
 2件: HDAC4_5, HDAC4_5 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
19 Apelin signaling pathway 💬
 3件: HDAC4_5, HDAC4_5, PIK3C3 💬 Fimepinostat 💬 Fimepinostat 1件: 75 💬
20 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
21 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
22 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
23 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
24 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
25 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
26 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
27 Apelin signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
28 Apelin signaling pathway 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
29 Apelin signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
30 Apelin signaling pathway 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
31 Apelin signaling pathway 💬
 3件: MYL2, MYL3, MYL4 💬 Aficamten 💬 Aficamten 1件: 58 💬
32 Apelin signaling pathway 💬
 3件: NOS1, NOS2, NOS3 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
33 Apelin signaling pathway 💬
 1件: PDE3B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
34 Apelin signaling pathway 💬
 1件: PDE3B 💬 Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
35 Apelin signaling pathway 💬
 1件: PDE3B 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
36 Apelin signaling pathway 💬
 1件: PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
37 Apelin signaling pathway 💬
 1件: PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
38 Apelin signaling pathway 💬
 1件: PDE3B 💬 Caffeine citrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
39 Apelin signaling pathway 💬
 1件: PDE3B 💬 Cilostazol 💬 Cilostazol 5件:  6 , 46, 51, 70, 124 💬
40 Apelin signaling pathway 💬
 1件: PDE3B 💬 Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
41 Apelin signaling pathway 💬
 1件: PDE3B 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
42 Apelin signaling pathway 💬
 1件: PDE3B 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬
43 Apelin signaling pathway 💬
 1件: PDE3B 💬 Levosimendan 💬 Levosimendan 1件:  2  💬
44 Apelin signaling pathway 💬
 1件: PDE3B 💬 Milrinone 💬 Milrinone 1件: 294 💬
45 Apelin signaling pathway 💬
 1件: PDE3B 💬 Milrinone lactate 💬 Milrinone 1件: 294 💬
46 Apelin signaling pathway 💬
 1件: PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
47 Apelin signaling pathway 💬
 1件: PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
48 Apelin signaling pathway 💬
 1件: PDE3B 💬 Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
49 Apelin signaling pathway 💬
 1件: PLAT 💬 Aminocaproic acid 💬 Aminocaproic acid 1件: 70 💬
50 Apelin signaling pathway 💬
 2件: PRKAA, PRKAA 💬 Metformin 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
51 Apelin signaling pathway 💬
 2件: PRKAA, PRKAA 💬 Metformin hydrochloride 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
52 Apelin signaling pathway 💬
 1件: PRKCE 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
53 Apelin signaling pathway 💬
 1件: PRKCE 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
54 Apelin signaling pathway 💬
 1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
55 Apelin signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬