Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Apoptosis 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 Apoptosis 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 Apoptosis 💬
 1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
4 Apoptosis 💬
 1件: CTSC 💬 Brensocatib 💬 Brensocatib 1件: 299 💬
5 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
6 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
7 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
8 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
9 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
10 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
11 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
12 Apoptosis 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
13 Apoptosis 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬
14 Apoptosis 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
15 Apoptosis 💬
 1件: NGFB 💬 Tanezumab 💬 Tanezumab 2件: 226, 298 💬
16 Apoptosis 💬
 2件: PARP1, PARP2 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬
17 Apoptosis 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
18 Apoptosis 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
19 Apoptosis 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
20 Apoptosis 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
21 Apoptosis 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
22 Apoptosis 💬
 1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
23 Apoptosis 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
24 Apoptosis 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
25 Apoptosis 💬
 1件: RIPK1 💬 Eclitasertib 💬 SAR443122 1件: 97 💬
26 Apoptosis 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
27 Apoptosis 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
28 Apoptosis 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
29 Apoptosis 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
30 Apoptosis 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
31 Apoptosis 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
32 Apoptosis 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
33 Apoptosis 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
34 Apoptosis 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
35 Apoptosis 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
36 Apoptosis 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
37 Apoptosis - multiple species 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
38 Apoptosis - multiple species 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
39 Apoptosis - multiple species 💬
 1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
40 Apoptosis - multiple species 💬
 1件: NGFR 💬 Cenegermin 💬 Cenegermin 1件: 53 💬

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