Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 Chemical carcinogenesis - reactive oxygen species 💬
1件: ABL1 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
4 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
5 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
6 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
7 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
8 Chemical carcinogenesis - reactive oxygen species 💬
2件: ABL1, SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
9 Chemical carcinogenesis - reactive oxygen species 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
10 Chemical carcinogenesis - reactive oxygen species 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
11 Chemical carcinogenesis - reactive oxygen species 💬
2件: BRAF, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
12 Chemical carcinogenesis - reactive oxygen species 💬
2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
13 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
14 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
15 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
16 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
17 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
18 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
19 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
20 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
21 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
22 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
23 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
24 Chemical carcinogenesis - reactive oxygen species 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
25 Chemical carcinogenesis - reactive oxygen species 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
26 Chemical carcinogenesis - reactive oxygen species 💬
1件: KLHL19 💬 Dimethyl fumarate 💬 Dimethyl fumarate 6件: 13, 20, 49, 51, 86, 296 💬
27 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
28 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
29 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
30 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
31 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
32 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
33 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
34 Chemical carcinogenesis - reactive oxygen species 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
35 Chemical carcinogenesis - reactive oxygen species 💬
1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬
36 Chemical carcinogenesis - reactive oxygen species 💬
1件: MET 💬 Cabozantinib 💬 Cabozantinib 1件: 34 💬
37 Chemical carcinogenesis - reactive oxygen species 💬
1件: MET 💬 Cabozantinib s-malate 💬 Cabozantinib 1件: 34 💬
38 Chemical carcinogenesis - reactive oxygen species 💬
1件: NFE2L2 💬 Omaveloxolone 💬 Omaveloxolone 1件: 18 💬
39 Chemical carcinogenesis - reactive oxygen species 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
40 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 Warfarin sodium 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
41 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 Warfarin potassium 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
42 Chemical carcinogenesis - reactive oxygen species 💬
1件: NQO1 💬 Warfarin 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
43 Chemical carcinogenesis - reactive oxygen species 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
44 Chemical carcinogenesis - reactive oxygen species 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
45 Chemical carcinogenesis - reactive oxygen species 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
46 Chemical carcinogenesis - reactive oxygen species 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
47 Chemical carcinogenesis - reactive oxygen species 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
48 Chemical carcinogenesis - reactive oxygen species 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
49 Chemical carcinogenesis - reactive oxygen species 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
50 Chemical carcinogenesis - reactive oxygen species 💬
1件: PRKCD 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
51 Chemical carcinogenesis - reactive oxygen species 💬
1件: PRKCD 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
52 Chemical carcinogenesis - reactive oxygen species 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
53 Chemical carcinogenesis - reactive oxygen species 💬
1件: SOD1 💬 Tofersen 💬 Tofersen 1件:  2  💬
54 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬
55 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 8件: 13, 34, 85, 87, 89, 227, 280, 331 💬
56 Chemical carcinogenesis - reactive oxygen species 💬
1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬