Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Colorectal cancer 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 Colorectal cancer 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 Colorectal cancer 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
4 Colorectal cancer 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
5 Colorectal cancer 💬
2件: BRAF, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
6 Colorectal cancer 💬
2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
7 Colorectal cancer 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
8 Colorectal cancer 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
9 Colorectal cancer 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
10 Colorectal cancer 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
11 Colorectal cancer 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
12 Colorectal cancer 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
13 Colorectal cancer 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
14 Colorectal cancer 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
15 Colorectal cancer 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
16 Colorectal cancer 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
17 Colorectal cancer 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
18 Colorectal cancer 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
19 Colorectal cancer 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
20 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
21 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
22 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
23 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
24 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
25 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
26 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
27 Colorectal cancer 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
28 Colorectal cancer 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
29 Colorectal cancer 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
30 Colorectal cancer 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
31 Colorectal cancer 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
32 Colorectal cancer 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
33 Colorectal cancer 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
34 Colorectal cancer 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
35 Colorectal cancer 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
36 Colorectal cancer 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬