Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human immunodeficiency virus 1 infection 💬
 1件: ATR 💬 Tuvusertib 💬 Tuvusertib 1件: 65 💬
2 Human immunodeficiency virus 1 infection 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
3 Human immunodeficiency virus 1 infection 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
4 Human immunodeficiency virus 1 infection 💬
 1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
5 Human immunodeficiency virus 1 infection 💬
 1件: CCR5 💬 Cenicriviroc 💬 Cenicriviroc 1件: 94 💬
6 Human immunodeficiency virus 1 infection 💬
 1件: CCR5 💬 Cenicriviroc mesylate 💬 Cenicriviroc 1件: 94 💬
7 Human immunodeficiency virus 1 infection 💬
 1件: CCR5 💬 Maraviroc 💬 Maraviroc 1件: 46 💬
8 Human immunodeficiency virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
9 Human immunodeficiency virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Muromonab-CD3 💬 Muromonab 3件: 60, 96, 97 💬
10 Human immunodeficiency virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
11 Human immunodeficiency virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
12 Human immunodeficiency virus 1 infection 💬
 4件: CD3D, CD3E, CD3G, CD4 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
13 Human immunodeficiency virus 1 infection 💬
 1件: CD3E 💬 Elranatamab 💬 Elranatamab 1件: 28 💬
14 Human immunodeficiency virus 1 infection 💬
 1件: CD3E 💬 Imvotamab 💬 Imvotamab 2件: 46, 49 💬
15 Human immunodeficiency virus 1 infection 💬
 1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
16 Human immunodeficiency virus 1 infection 💬
 1件: CD3E 💬 Talquetamab 💬 Talquetamab 1件: 28 💬
17 Human immunodeficiency virus 1 infection 💬
 1件: CD3E 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
18 Human immunodeficiency virus 1 infection 💬
 1件: CD4 💬 Zanolimumab 💬 Zanolimumab 1件: 46 💬
19 Human immunodeficiency virus 1 infection 💬
 1件: CXCR4 💬 Mavorixafor 💬 Mavorixafor 1件: 65 💬
20 Human immunodeficiency virus 1 infection 💬
 1件: CXCR4 💬 Plerixafor 💬 Plerixafor 5件: 20, 51, 65, 285, 299 💬
21 Human immunodeficiency virus 1 infection 💬
 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
22 Human immunodeficiency virus 1 infection 💬
 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
23 Human immunodeficiency virus 1 infection 💬
 1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
24 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
25 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
26 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
27 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
28 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
29 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
30 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
31 Human immunodeficiency virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
32 Human immunodeficiency virus 1 infection 💬
 6件: MHC1, MHC1, MHC1, MHC1, MHC1, MHC1 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
33 Human immunodeficiency virus 1 infection 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
34 Human immunodeficiency virus 1 infection 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
35 Human immunodeficiency virus 1 infection 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
36 Human immunodeficiency virus 1 infection 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
37 Human immunodeficiency virus 1 infection 💬
 4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
38 Human immunodeficiency virus 1 infection 💬
 4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
39 Human immunodeficiency virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
40 Human immunodeficiency virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
41 Human immunodeficiency virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
42 Human immunodeficiency virus 1 infection 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
43 Human immunodeficiency virus 1 infection 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
44 Human immunodeficiency virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Cyclosporine 💬 Cyclosporine 42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
45 Human immunodeficiency virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬
46 Human immunodeficiency virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
47 Human immunodeficiency virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
48 Human immunodeficiency virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬
49 Human immunodeficiency virus 1 infection 💬
 1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
50 Human immunodeficiency virus 1 infection 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
51 Human immunodeficiency virus 1 infection 💬
 1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
52 Human immunodeficiency virus 1 infection 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
53 Human immunodeficiency virus 1 infection 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
54 Human immunodeficiency virus 1 infection 💬
 1件: RIPK1 💬 Eclitasertib 💬 SAR443122 1件: 97 💬
55 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
56 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
57 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
58 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
59 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
60 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
61 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
62 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
63 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
64 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
65 Human immunodeficiency virus 1 infection 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬