Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Integrin signaling 💬
 1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 223 💬
2 Integrin signaling 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
3 Integrin signaling 💬
 1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
4 Integrin signaling 💬
 1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
5 Integrin signaling 💬
 1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
6 Integrin signaling 💬
 1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
7 Integrin signaling 💬
 2件: EGFR, ERBB2 💬 Afatinib 💬 Afatinib 1件: 285 💬
8 Integrin signaling 💬
 2件: EGFR, ERBB2 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
9 Integrin signaling 💬
 2件: EGFR, ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
10 Integrin signaling 💬
 2件: EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
11 Integrin signaling 💬
 2件: EGFR, ERBB2 💬 Neratinib 💬 Neratinib 1件: 34 💬
12 Integrin signaling 💬
 2件: EGFR, ERBB2 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
13 Integrin signaling 💬
 4件: EGFR, ERBB2, FLT4, KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
14 Integrin signaling 💬
 3件: FLT1, FLT4, KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
15 Integrin signaling 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
16 Integrin signaling 💬
 3件: FLT1, FLT4, KDR 💬 Cediranib maleate 💬 Cediranib 1件: 34 💬
17 Integrin signaling 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
18 Integrin signaling 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
19 Integrin signaling 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
20 Integrin signaling 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
21 Integrin signaling 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
22 Integrin signaling 💬
 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
23 Integrin signaling 💬
 3件: FLT4, KDR, PDGFRB 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
24 Integrin signaling 💬
 3件: FLT4, KDR, PDGFRB 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
25 Integrin signaling 💬
 1件: ICAM1 💬 Alicaforsen sodium 💬 Alicaforsen 2件: 96, 97 💬
26 Integrin signaling 💬
 1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
27 Integrin signaling 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
28 Integrin signaling 💬
 1件: IGF1R 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
29 Integrin signaling 💬
 1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 49 💬
30 Integrin signaling 💬
 1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬
31 Integrin signaling 💬
 1件: ITGA4 💬 Natalizumab 💬 Natalizumab 5件: 13, 15, 25, 46, 96 💬
32 Integrin signaling 💬
 3件: ITGA4, ITGB1, ITGB7 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
33 Integrin signaling 💬
 2件: ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬
34 Integrin signaling 💬
 2件: ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬
35 Integrin signaling 💬
 3件: ITGA5, ITGB1, ITGB6 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
36 Integrin signaling 💬
 1件: ITGAL 💬 Efalizumab 💬 Efalizumab 10件: 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬
37 Integrin signaling 💬
 1件: ITGB2 💬 Marnetegragene autotemcel 💬 RP-L201 1件: 65 💬
38 Integrin signaling 💬
 1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬
39 Integrin signaling 💬
 2件: KDR, MET 💬 Cabozantinib 💬 Cabozantinib 9件: 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
40 Integrin signaling 💬
 2件: KDR, MET 💬 Cabozantinib s-malate 💬 Cabozantinib 9件: 13, 34, 46, 49, 50, 51, 53, 96, 97 💬
41 Integrin signaling 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 12件: 34, 67, 89, 96, 137, 157, 158, 228, 277, 278, 279, 280 💬
42 Integrin signaling 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
43 Integrin signaling 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
44 Integrin signaling 💬
 1件: PDGFRA 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
45 Integrin signaling 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
46 Integrin signaling 💬
 2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
47 Integrin signaling 💬
 2件: PDGFRA, PDGFRB 💬 Seralutinib 💬 Seralutinib 1件: 86 💬
48 Integrin signaling 💬
 2件: PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib 3件: 13, 51, 85 💬
49 Integrin signaling 💬
 2件: PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib 3件: 13, 51, 85 💬
50 Integrin signaling 💬
 3件: PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬
51 Integrin signaling 💬
 1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
52 Integrin signaling 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
53 Integrin signaling 💬
 2件: PIK3CA, PIK3CD 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
54 Integrin signaling 💬
 1件: PIK3CD 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
55 Integrin signaling 💬
 1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
56 Integrin signaling 💬
 1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
57 Integrin signaling 💬
 1件: SRC 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
58 Integrin signaling 💬
 1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
59 Integrin signaling 💬
 1件: TGFB1 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 222, 274 💬
60 Integrin signaling 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
61 Integrin signaling 💬
 1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
62 Integrin signaling 💬
 1件: VWF 💬 Caplacizumab 💬 Caplacizumab 2件: 63, 64 💬