Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Measles 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 Measles 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 Measles 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
4 Measles 💬
1件: CD28 💬 Acazicolcept 💬 Acazicolcept 1件: 49 💬
5 Measles 💬
3件: CD3D, CD3E, CD3G 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
6 Measles 💬
3件: CD3D, CD3E, CD3G 💬 Muromonab-CD3 💬 Muromonab 3件: 60, 96, 97 💬
7 Measles 💬
3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
8 Measles 💬
3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
9 Measles 💬
4件: CD3D, CD3E, CD3G, IL2RA 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
10 Measles 💬
1件: CD3E 💬 Elranatamab 💬 Elranatamab 1件: 28 💬
11 Measles 💬
1件: CD3E 💬 Imvotamab 💬 Imvotamab 2件: 46, 49 💬
12 Measles 💬
1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
13 Measles 💬
1件: CD3E 💬 Talquetamab 💬 Talquetamab 1件: 28 💬
14 Measles 💬
1件: CD3E 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
15 Measles 💬
2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
16 Measles 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
17 Measles 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
18 Measles 💬
2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
19 Measles 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
20 Measles 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
21 Measles 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
22 Measles 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
23 Measles 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
24 Measles 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
25 Measles 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
26 Measles 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
27 Measles 💬
1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
28 Measles 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
29 Measles 💬
1件: IL1A 💬 Bermekimab 💬 Bermekimab 1件: 51 💬
30 Measles 💬
2件: IL1A, IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
31 Measles 💬
2件: IL1A, IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
32 Measles 💬
3件: IL1A, IL1B, IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
33 Measles 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
34 Measles 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
35 Measles 💬
1件: IL2RA 💬 Basiliximab 💬 Basiliximab 5件:  2 , 50, 97, 222, 228 💬
36 Measles 💬
1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
37 Measles 💬
3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
38 Measles 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
39 Measles 💬
1件: IL6 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
40 Measles 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
41 Measles 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
42 Measles 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
43 Measles 💬
1件: JAK1 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
44 Measles 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
45 Measles 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
46 Measles 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
47 Measles 💬
1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
48 Measles 💬
1件: JAK1 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
49 Measles 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
50 Measles 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
51 Measles 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
52 Measles 💬
2件: JAK1, JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
53 Measles 💬
2件: JAK1, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
54 Measles 💬
3件: JAK1, JAK3, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
55 Measles 💬
3件: JAK1, JAK3, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
56 Measles 💬
3件: JAK1, JAK3, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
57 Measles 💬
3件: JAK1, JAK3, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
58 Measles 💬
1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
59 Measles 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
60 Measles 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
61 Measles 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
62 Measles 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
63 Measles 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
64 Measles 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
65 Measles 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
66 Measles 💬
1件: TLR7 💬 Enpatoran 💬 Enpatoran 1件: 49 💬
67 Measles 💬
1件: TLR7 💬 Imiquimod 💬 Imiquimod 2件: 34, 51 💬
68 Measles 💬
1件: TLR9 💬 Cobitolimod 💬 Cobitolimod 1件: 97 💬
69 Measles 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
70 Measles 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬